Wang, Liqin

Reversible and adaptive resistance to BRAF(V600E) inhibition in melanoma

Sun, C., Wang, L., Huang, S., Heynen, G. J. J. E., Prahallad, A., Robert, C., Haanen, J., Blank, C., Wesseling, J., Willems, S. M., et al. (2014) · Nature

Melanoma and MAPK PathwaysLung Cancer Treatments and Mutations

Cited by 888

Exploiting senescence for the treatment of cancer

Wang, L., Lankhorst, L., & Bernards, R. (2022) · Nature Reviews Cancer

Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms

Cited by 867

Rational combinations of targeted cancer therapies: background, advances and challenges

Jin, H., Wang, L., & Bernards, R. (2023) · Nature Reviews Drug Discovery

Lung Cancer Treatments and MutationsCancer Genomics and Diagnostics

Cited by 503

Inducing and exploiting vulnerabilities for the treatment of liver cancer

Wang, C., Vegna, S., Jin, H., Benedict, B., Lieftink, C., Ramirez, C., de Oliveira, R. L., Morris, B., Gadiot, J., Wang, W., et al. (2019) · Nature

Telomeres, Telomerase, and SenescenceHepatocellular Carcinoma Treatment and Prognosis

Cited by 427

High-Throughput Functional Genetic and Compound Screens Identify Targets for Senescence Induction in Cancer

Wang, L., Leite de Oliveira, R., Wang, C., Fernandes Neto, J. M., Mainardi, S., Evers, B., Lieftink, C., Morris, B., Jochems, F., Willemsen, L., et al. (2017) · Cell Reports

Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms

Cited by 224

The Cancer SENESCopedia: A delineation of cancer cell senescence

Jochems, F., Thijssen, B., De Conti, G., Jansen, R., Pogacar, Z., Groot, K., Wang, L., Schepers, A., Wang, C., Jin, H., et al. (2021) · Cell Reports

Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms

Cited by 201

Taking advantage of drug resistance, a new approach in the war on cancer

Wang, L., & Bernards, R. (2018) · Frontiers of Medicine

Lung Cancer Treatments and MutationsCancer Genomics and Diagnostics

Cited by 53

Paneth-like transition drives resistance to dual targeting of KRAS and EGFR in colorectal cancer

Zhang, Y., Chen, J., She, Y., Fang, Z., Zhang, Y., Ruan, D., Guo, W., Liao, J., Zhou, W., Lao, J., et al. (2026) · Cancer Cell

Colorectal Cancer Treatments and StudiesCancer Cells and Metastasis

Cited by 23

Indisulam synergizes with palbociclib to induce senescence through inhibition of CDK2 kinase activity

Pogacar, Z., Johnson, J. L., Krenning, L., De Conti, G., Jochems, F., Lieftink, C., Velds, A., Wardak, L., Groot, K., Schepers, A., et al. (2022) · PLOS ONE

Telomeres, Telomerase, and SenescenceAdvanced Breast Cancer Therapies

Cited by 13

Indisulam synergizes with palbociclib to induce senescence through inhibition of CDK2 kinase activity

Pogacar, Z., Johnson, J. L., Krenning, L., De Conti, G., Lieftink, C., Velds, A., Wardak, L., Jochems, F., Groot, K., Schepers, A., et al. (2021) · PLoS ONE

Telomeres, Telomerase, and SenescenceAdvanced Breast Cancer Therapies

Cited by 13