Gregory, Philip D

Highly efficient homology-driven genome editing in human T cells by combining zinc-finger nuclease mRNA and AAV6 donor delivery

Wang, J., DeClercq, J. J., Hayward, S. B., Li, P. W.-L., Shivak, D. A., Gregory, P. D., Lee, G., & Holmes, M. C. (2016) · Nucleic Acids Research

CRISPR and Genetic EngineeringVirus-based gene therapy research

Cited by 128

Efficient clinical scale gene modification via zinc finger nuclease-targeted disruption of the HIV co-receptor CCR5

Maier, D. A., Brennan, A. L., Jiang, S., Binder-Scholl, G. K., Lee, G., Plesa, G., Zheng, Z., Cotte, J., Carpenito, C., Wood, T., et al. (2013) · Human Gene Therapy

Virus-based gene therapy researchCRISPR and Genetic Engineering

Cited by 126

Generation of a triple-gene knockout mammalian cell line using engineered zinc-finger nucleases

Liu, P., Chan, E. M., Cost, G. J., Zhang, L., Wang, J., Miller, J. C., Guschin, D. Y., Reik, A., Holmes, M. C., Mott, J. E., et al. (2010) · Biotechnology and Bioengineering

CRISPR and Genetic EngineeringAnimal Genetics and Reproduction

Cited by 107

Zinc-finger nuclease editing of human cxcr4 promotes HIV-1 CD4(+) T cell resistance and enrichment

Yuan, J., Wang, J., Crain, K., Fearns, C., Kim, K. A., Hua, K. L., Gregory, P. D., Holmes, M. C., & Torbett, B. E. (2012) · Molecular Therapy

HIV Research and TreatmentCRISPR and Genetic Engineering

Cited by 105

Ocular gene transfer with self-complementary AAV vectors

Yokoi, K., Kachi, S., Zhang, H. S., Gregory, P. D., Spratt, S. K., Samulski, R. J., & Campochiaro, P. A. (2007) · Investigative Opthalmology & Visual Science

Virus-based gene therapy researchRetinal Development and Disorders

Cited by 58

Zinc Finger Nucleases Targeting The β-Globin Locus Drive Efficient Correction Of The Sickle Mutation In CD34+ Cells

Hoban, M. D., Joglekar, A. V., Gray, D., Kaufman, M. L., Urbinati, F., Senadheera, S., Cost, G., Reik, A., Holmes, M. C., Gregory, P. D., et al. (2013) · Blood

Hemoglobinopathies and Related DisordersCRISPR and Genetic Engineering

Cited by 2