Takahashi, Yusuke

RPE65 is the isomerohydrolase in the retinoid visual cycle

Moiseyev, G., Chen, Y., Takahashi, Y., Wu, B. X., & Ma, J.-X. (2005) · Proceedings of the National Academy of Sciences

Retinal Development and DisordersRetinoids in leukemia and cellular processes

Cited by 536

RPE65 Is an Iron(II)-dependent Isomerohydrolase in the Retinoid Visual Cycle

Moiseyev, G., Takahashi, Y., Chen, Y., Gentleman, S., Redmond, T. M., Crouch, R. K., & Ma, J.-X. (2006) · Journal of Biological Chemistry

Retinal Development and DisordersRetinoids in leukemia and cellular processes

Cited by 119

RPE65 Gene Delivery Restores Isomerohydrolase Activity and Prevents Early Cone Loss in Rpe65−/−Mice

Chen, Y., Moiseyev, G., Takahashi, Y., & Ma, J.-X. (2006) · Investigative Opthalmology & Visual Science

Retinal Development and DisordersRetinal Diseases and Treatments

Cited by 80

Identification of conserved histidines and glutamic acid as key residues for isomerohydrolase activity of RPE65, an enzyme of the visual cycle in the retinal pigment epithelium

Takahashi, Y., Moiseyev, G., Chen, Y., & Ma, J.-X. (2005) · FEBS Letters

Retinal Development and DisordersPhotoreceptor and optogenetics research

Cited by 54

Negative charge of the glutamic acid 417 residue is crucial for isomerohydrolase activity of RPE65

Nikolaeva, O., Takahashi, Y., Moiseyev, G., & Ma, J.-X. (2010) · Biochemical and Biophysical Research Communications

Retinal Development and DisordersRetinoids in leukemia and cellular processes

Cited by 14

ADAM17 mediates ectodomain shedding of the soluble VLDL receptor fragment in the retinal epithelium

Ma, X., Takahashi, Y., Wu, W., Liang, W., Chen, J., Chakraborty, D., Li, Y., Du, Y., Benyajati, S., & Ma, J.-X. (2021) · Journal of Biological Chemistry

Protease and Inhibitor MechanismsRetinal Diseases and Treatments

Cited by 9

Energy paradox in REM sleep: balancing supply and consumption in brain metabolism

Takahashi, Y., Ikoma, Y., & Matsui, K. (2026) · Communications Biology

Sleep and Wakefulness ResearchNeuroscience and Neuropharmacology Research

Cited by 1