Ke, Dan

A novel small-molecule PROTAC selectively promotes tau clearance to improve cognitive functions in Alzheimer-like models

Wang, W., Zhou, Q., Jiang, T., Li, S., Ye, J., Zheng, J., Wang, X., Liu, Y., Deng, M., Ke, D., et al. (2021) · Theranostics

Alzheimer's disease research and treatmentsProtein Degradation and Inhibitors

Cited by 242

Moringa Oleifera Alleviates Homocysteine-Induced Alzheimer’s Disease-Like Pathology and Cognitive Impairments

Mahaman, Y. A. R., Huang, F., Wu, M., Wang, Y., Wei, Z., Bao, J., Salissou, M. T. M., Ke, D., Wang, Q., Liu, R., et al. (2018) · Journal of Alzheimer s Disease

Alzheimer's disease research and treatmentsMoringa oleifera research and applications

Cited by 93

Tau accumulation triggers STAT1‐dependent memory deficits by suppressing NMDA receptor expression

Li, X., Hong, X., Wang, Y., Zhang, S., Zhang, J., Li, X., Liu, Y., Sun, D., Feng, Q., Ye, J., et al. (2019) · The EMBO Reports

Alzheimer's disease research and treatmentsNeuroscience and Neuropharmacology Research

Cited by 81

BACE1 SUMOylation increases its stability and escalates the protease activity in Alzheimer’s disease

Bao, J., Qin, M., Mahaman, Y. A. R., Zhang, B., Huang, F., Zeng, K., Xia, Y., Ke, D., Wang, Q., Liu, R., et al. (2018) · Proceedings of the National Academy of Sciences

Alzheimer's disease research and treatmentsUbiquitin and proteasome pathways

Cited by 50

CIP2A-promoted astrogliosis induces AD-like synaptic degeneration and cognitive deficits

Shentu, Y.-P., Hu, W.-T., Zhang, Q., Huo, Y., Liang, J.-W., Liuyang, Z.-Y., Zhou, H., Wei, H., Ke, D., Wang, X.-C., et al. (2019) · Neurobiology of Aging

Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 21