Housman, David E.

Hypoxia-mediated selection of cells with diminished apoptotic potential in solid tumours

Graeber, T. G., Osmanian, C., Jacks, T., Housman, D. E., Koch, C. J., Lowe, S. W., & Giaccia, A. J. (1996) · Nature

Cell death mechanisms and regulationCancer, Hypoxia, and Metabolism

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Cloning of Human Mineralocorticoid Receptor Complementary DNA: Structural and Functional Kinship with the Glucocorticoid Receptor

Arriza, J. L., Weinberger, C., Cerelli, G., Glaser, T. M., Handelin, B. L., Housman, D. E., & Evans, R. M. (1987) · Science

Hormonal Regulation and HypertensionEstrogen and related hormone effects

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The dominant-white spotting (W) locus of the mouse encodes the c-kit proto-oncogene

Geissler, E. N., Ryan, M. A., & Housman, D. E. (1988) · Cell

Hematopoietic Stem Cell Transplantationmelanin and skin pigmentation

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Histone deacetylase inhibitors arrest polyglutamine-dependent neurodegeneration in Drosophila

Steffan, J. S., Bodai, L., Pallos, J., Poelman, M., McCampbell, A., Apostol, B. L., Kazantsev, A., Schmidt, E., Zhu, Y.-Z., Greenwald, M., et al. (2001) · Nature

Genetic Neurodegenerative DiseasesHistone Deacetylase Inhibitors Research

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Transcriptome-wide Regulation of Pre-mRNA Splicing and mRNA Localization by Muscleblind Proteins

Wang, E. T., Cody, N. A. L., Jog, S., Biancolella, M., Wang, T. T., Treacy, D. J., Luo, S., Schroth, G. P., Housman, D. E., Reddy, S., et al. (2012) · Cell

RNA Research and SplicingMuscle Physiology and Disorders

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Tissue specific expression of FMR-1 provides evidence for a functional role in fragile X syndrome

Hinds, H. L., Ashley, C. T., Sutcliffe, J. S., Nelson, D. L., Warren, S. T., Housman, D. E., & Schalling, M. (1993) · Nature Genetics

Genetics and Neurodevelopmental DisordersWilliams Syndrome Research

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Detection of long repeat expansions from PCR-free whole-genome sequence data

Dolzhenko, E., van Vugt, J. J. F. A., Shaw, R. J., Bekritsky, M. A., van Blitterswijk, M., Narzisi, G., Ajay, S. S., Rajan, V., Lajoie, B. R., Johnson, N. H., et al. (2017) · Genome Research

Genomics and Rare DiseasesGenomics and Phylogenetic Studies

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Potential function for the Huntingtin protein as a scaffold for selective autophagy

Ochaba, J., Lukacsovich, T., Csikos, G., Zheng, S., Margulis, J., Salazar, L., Mao, K., Lau, A. L., Yeung, S. Y., Humbert, S., et al. (2014) · Proceedings of the National Academy of Sciences

Genetic Neurodegenerative DiseasesAutophagy in Disease and Therapy

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mTORC1 promotes survival through translational control of Mcl-1

Mills, J. R., Hippo, Y., Robert, F., Chen, S. M. H., Malina, A., Lin, C.-J., Trojahn, U., Wendel, H.-G., Charest, A., Bronson, R. T., et al. (2008) · Proceedings of the National Academy of Sciences

PI3K/AKT/mTOR signaling in cancerCell death mechanisms and regulation

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Huntington’s Disease iPSC-Derived Brain Microvascular Endothelial Cells Reveal WNT-Mediated Angiogenic and Blood-Brain Barrier Deficits

Lim, R. G., Quan, C., Reyes-Ortiz, A. M., Lutz, S. E., Kedaigle, A. J., Gipson, T. A., Wu, J., Vatine, G. D., Stocksdale, J., Casale, M. S., et al. (2017) · Cell Reports

Barrier Structure and Function StudiesDrug Transport and Resistance Mechanisms

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Developmental alterations in Huntington’s disease neural cells and pharmacological rescue in cells and mice

The HD iPSC Consortium, Lim, R. G., Salazar, L. L., Wilton, D. K., King, A. R., Stocksdale, J. T., Sharifabad, D., Lau, A. L., Stevens, B., Reidling, J. C., et al. (2017) · Nature Neuroscience

Genetic Neurodegenerative DiseasesPluripotent Stem Cells Research

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Mouse β-Globin DNA-Binding Protein B1 is Identical to a Proto-Oncogene, the Transcription Factor Spi-1 /PU.1, and is Restricted in Expression to Hematopoietic Cells and the Testis

Galson, D. L., Hensold, J. O., Bishop, T. R., Schalling, M., D'Andrea, A. D., Jones, C., Auron, P. E., & Housman, D. E. (1993) · Molecular and Cellular Biology

Genomics and Chromatin DynamicsHematopoietic Stem Cell Transplantation

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CalDAG-GEFI mediates striatal cholinergic modulation of dendritic excitability, synaptic plasticity and psychomotor behaviors

Crittenden, J. R., Zhai, S., Sauvage, M., Kitsukawa, T., Burguière, E., Thomsen, M., Zhang, H., Costa, C., Martella, G., Ghiglieri, V., et al. (2021) · Neurobiology of Disease

Neuroscience and Neuropharmacology ResearchNeurotransmitter Receptor Influence on Behavior

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