Humphreys, Ian R.

Generalized biomolecular modeling and design with RoseTTAFold All-Atom

Krishna, R., Wang, J., Ahern, W., Sturmfels, P., Venkatesh, P., Kalvet, I., Lee, G. R., Morey-Burrows, F. S., Anishchenko, I., Humphreys, I. R., et al. (2024) · Science

Protein Structure and DynamicsMachine Learning in Bioinformatics

Cited by 978

Computed structures of core eukaryotic protein complexes

Humphreys, I. R., Pei, J., Baek, M., Krishnakumar, A., Anishchenko, I., Ovchinnikov, S., Zhang, J., Ness, T. J., Banjade, S., Bagde, S. R., et al. (2021) · Science

Protein Structure and DynamicsMachine Learning in Bioinformatics

Cited by 542

Structures of core eukaryotic protein complexes

Humphreys, I. R., Pei, J., Baek, M., Krishnakumar, A., Anishchenko, I., Ovchinnikov, S., Zhang, J., Ness, T. J., Banjade, S., Bagde, S., et al. (2021) · Science

Protein Structure and DynamicsMachine Learning in Bioinformatics

Cited by 541

Computational design of serine hydrolases

Lauko, A., Pellock, S. J., Sumida, K. H., Anishchenko, I., Juergens, D., Ahern, W., Jeung, J., Shida, A. F., Hunt, A., Kalvet, I., et al. (2025) · Science

Protein Structure and DynamicsEnzyme Catalysis and Immobilization

Cited by 235

Ecophylogenetics Clarifies the Evolutionary Association between Mammals and Their Gut Microbiota

Gaulke, C. A., Arnold, H. K., Humphreys, I. R., Kembel, S. W., O’Dwyer, J. P., & Sharpton, T. J. (2018) · mBio

Gut microbiota and healthEvolution and Paleontology Studies

Cited by 117

Genetic manipulation of Patescibacteria provides mechanistic insights into microbial dark matter and the epibiotic lifestyle

Wang, Y., Gallagher, L. A., Andrade, P. A., Liu, A., Humphreys, I. R., Turkarslan, S., Cutler, K. J., Arrieta-Ortiz, M. L., Li, Y., Radey, M. C., et al. (2023) · Cell

Bacterial Genetics and BiotechnologyMicrobial Community Ecology and Physiology

Cited by 108

Generalized Biomolecular Modeling and Design with RoseTTAFold All-Atom

Krishna, R., Wang, J., Ahern, W., Sturmfels, P., Venkatesh, P., Kalvet, I., Lee, G. R., Morey-Burrows, F. S., Anishchenko, I., Humphreys, I. R., et al. (2023) · bioRxiv (Cold Spring Harbor Laboratory)

Protein Structure and DynamicsComputational Drug Discovery Methods

Cited by 106

Predicting protein-protein interactions in the human proteome

Zhang, J., Humphreys, I. R., Pei, J., Kim, J., Choi, C., Yuan, R., Durham, J., Liu, S., Choi, H.-J., Baek, M., et al. (2025) · Science

Bioinformatics and Genomic NetworksProtein Structure and Dynamics

Cited by 87

Rapid and accurate prediction of protein homo-oligomer symmetry using Seq2Symm

Kshirsagar, M., Meller, A., Humphreys, I. R., Sledzieski, S., Xu, Y., Dodhia, R., Horvitz, E., Berger, B., Bowman, G. R., Ferres, J. L., et al. (2025) · Nature Communications

Protein Structure and DynamicsMachine Learning in Bioinformatics

Cited by 23

Rapid and accurate prediction of protein homo-oligomer symmetry with Seq2Symm

Kshirsagar, M., Meller, A., Humphreys, I., Sledzieski, S., Xu, Y., Dodhia, R., Horvitz, E., Berger, B., Bowman, G., Ferres, J. L., et al. (2024) · Nature Communications

Protein Structure and DynamicsMachine Learning in Bioinformatics

Cited by 22

Protein oligomer modeling guided by predicted interchain contacts in CASP14

Baek, M., Anishchenko, I., Park, H., Humphreys, I. R., & Baker, D. (2021) · Proteins: Structure, Function, and Bioinformatics

Protein Structure and DynamicsEnzyme Structure and Function

Cited by 18

Computational design of serine hydrolases

Lauko, A., Pellock, S. J., Anischanka, I., Sumida, K. H., Juergens, D., Ahern, W., Shida, A., Hunt, A., Kalvet, I., Norn, C., et al. (2024) · bioRxiv (Cold Spring Harbor Laboratory)

Protein Structure and DynamicsEnzyme Catalysis and Immobilization

Cited by 16