Rothe, Michael

Gene therapy for Wiskott-Aldrich syndrome–long-term efficacy and genotoxicity

Braun, C. J., Boztug, K., Paruzynski, A., Witzel, M., Schwarzer, A., Rothe, M., Modlich, U., Beier, R., Göhring, G., Steinemann, D., et al. (2014) · Science Translational Medicine

Virus-based gene therapy researchImmunodeficiency and Autoimmune Disorders

Cited by 562

Bromo- and Extraterminal Domain Chromatin Regulators Serve as Cofactors for Murine Leukemia Virus Integration

Gupta, S. S., Maetzig, T., Maertens, G. N., Sharif, A., Rothe, M., Weidner-Glunde, M., Galla, M., Schambach, A., Cherepanov, P., & Schulz, T. F. (2013) · Journal of Virology

Virus-based gene therapy researchHIV Research and Treatment

Cited by 139

Preclinical Evaluation of Efficacy and Safety of an Improved Lentiviral Vector for the Treatment of β-Thalassemia and Sickle Cell Disease

Negre, O., Bartholomae, C., Beuzard, Y., Cavazzana, M., Christiansen, L., Courne, C., Deichmann, A., Denaro, M., Dreuzy, E., Finer, M., et al. (2014) · Current Gene Therapy

Virus-based gene therapy researchHemoglobinopathies and Related Disorders

Cited by 126

Biosafety Challenges for Use of Lentiviral Vectors in Gene Therapy

Rothe, M., Modlich, U., & Schambach, A. (2014) · Current Gene Therapy

Virus-based gene therapy researchCRISPR and Genetic Engineering

Cited by 110

Preclinical evaluation of a novel lentiviral vector driving lineage-specific BCL11A knockdown for sickle cell gene therapy

Brendel, C., Negre, O., Rothe, M., Guda, S., Parsons, G., Harris, C., McGuinness, M., Abriss, D., Tsytsykova, A., Klatt, D., et al. (2020) · Molecular Therapy - Methods & Clinical Development

Virus-based gene therapy researchHemoglobinopathies and Related Disorders

Cited by 72