Ward, Lucas D.

Integrative analysis of 111 reference human epigenomes

Roadmap Epigenomics Consortium, Kundaje, A., Meuleman, W., Ernst, J., Bilenky, M., Yen, A., Heravi-Moussavi, A., Kheradpour, P., Zhang, Z., Wang, J., et al. (2015) · Nature

Genomics and Chromatin DynamicsEpigenetics and DNA Methylation

Cited by 6,368

The Genotype-Tissue Expression (GTEx) pilot analysis: Multitissue gene regulation in humans

The GTEx Consortium, Ardlie, K. G., Deluca, D. S., Segrè, A. V., Sullivan, T. J., Young, T. R., Gelfand, E. T., Trowbridge, C. A., Maller, J. B., Tukiainen, T., et al. (2015) · Science

Genetic Associations and EpidemiologyGenomics and Chromatin Dynamics

Cited by 5,062

Mapping and analysis of chromatin state dynamics in nine human cell types

Ernst, J., Kheradpour, P., Mikkelsen, T. S., Shoresh, N., Ward, L. D., Epstein, C. B., Zhang, X., Wang, L., Issner, R., Coyne, M., et al. (2011) · Nature

Genomics and Chromatin DynamicsChromatin Remodeling and Cancer

Cited by 2,898

HaploReg: a resource for exploring chromatin states, conservation, and regulatory motif alterations within sets of genetically linked variants

Ward, L. D., & Kellis, M. (2012) · Nucleic Acids Research

Genetic Associations and EpidemiologyGenomics and Chromatin Dynamics

Cited by 2,229

Plasma proteomic associations with genetics and health in the UK Biobank

Sun, B. B., Chiou, J., Traylor, M., Benner, C., Hsu, Y.-H., Richardson, T. G., Surendran, P., Mahajan, A., Robins, C., Vasquez-Grinnell, S. G., et al. (2023) · Nature

Genetic Associations and EpidemiologyBioinformatics and Genomic Networks

Cited by 1,880

Genetic regulation of the human plasma proteome in 54,306 UK Biobank participants

Sun, B. B., Chiou, J., Traylor, M., Benner, C., Hsu, Y.-H., Richardson, T. G., Surendran, P., Mahajan, A., Robins, C., Vasquez-Grinnell, S. G., et al. (2022) · Nature

Genetic Associations and EpidemiologyBioinformatics and Genomic Networks

Cited by 1,833

A high-resolution map of human evolutionary constraint using 29 mammals

Broad Institute Sequencing Platform and Whole Genome Assembly Team, Lindblad-Toh, K., Baylor College of Medicine Human Genome Sequencing Center Sequencing Team, Genome Institute at Washington University, Garber, M., Zuk, O., Lin, M. F., Parker, B. J., Washietl, S., Kheradpour, P., et al. (2011) · Nature

Genomics and Phylogenetic StudiesChromosomal and Genetic Variations

Cited by 1,108

Parental influence on human germline de novo mutations in 1,548 trios from Iceland

Jónsson, H., Sulem, P., Kehr, B., Kristmundsdottir, S., Zink, F., Hjartarson, E., Hardarson, M. T., Hjorleifsson, K. E., Eggertsson, H. P., Gudjonsson, S. A., et al. (2017) · Nature

Genomics and Rare DiseasesGenomic variations and chromosomal abnormalities

Cited by 561

Common Genetic Variants Modulate Pathogen-Sensing Responses in Human Dendritic Cells

Lee, M. N., Ye, C., Villani, A.-C., Raj, T., Li, W., Eisenhaure, T. M., Imboywa, S. H., Chipendo, P. I., Ran, F. A., Slowikowski, K., et al. (2014) · Science

interferon and immune responsesImmune Response and Inflammation

Cited by 442

Advancing human genetics research and drug discovery through exome sequencing of the UK Biobank

Szustakowski, J. D., Balasubramanian, S., Kvikstad, E., Khalid, S., Bronson, P. G., Sasson, A., Wong, E., Liu, D., Wade Davis, J., Haefliger, C., et al. (2021) · Nature Genetics

Genetic Associations and EpidemiologyGenomics and Rare Diseases

Cited by 401

Effect of predicted protein-truncating genetic variants on the human transcriptome

Rivas, M. A., Pirinen, M., Conrad, D. F., Lek, M., Tsang, E. K., Karczewski, K. J., Maller, J. B., Kukurba, K. R., DeLuca, D. S., Fromer, M., et al. (2015) · Science

Genomics and Rare DiseasesRNA Research and Splicing

Cited by 313

Evidence of Abundant Purifying Selection in Humans for Recently Acquired Regulatory Functions

Ward, L. D., & Kellis, M. (2012) · Science

Evolution and Genetic DynamicsChromosomal and Genetic Variations

Cited by 209

Advancing diagnosis and management of liver disease in adults through exome sequencing

Zheng, M., Hakim, A., Konkwo, C., Deaton, A. M., Ward, L. D., Silveira, M. G., Assis, D. N., Liapakis, A., Jaffe, A., Jiang, Z. G., et al. (2023) · EBioMedicine

Genomics and Rare DiseasesMetabolism and Genetic Disorders

Cited by 34

A proteomic platform to identify off-target proteins associated with therapeutic modalities that induce protein degradation or gene silencing

Liu, X., Zhang, Y., Ward, L. D., Yan, Q., Bohnuud, T., Hernandez, R., Lao, S., Yuan, J., & Fan, F. (2021) · Scientific Reports

Advanced Proteomics Techniques and ApplicationsProtein Degradation and Inhibitors

Cited by 21

Interpreting noncoding genetic variation in complex traits and human disease

Ward, L. D., & Kellis, M. (2012) · Nature Biotechnology

Genetic Associations and EpidemiologyGenomics and Rare Diseases

Cited by 6