Hansen, Arne

Development of a drug screening platform based on engineered heart tissue

Hansen, A., Eder, A., Bönstrup, M., Flato, M., Mewe, M., Schaaf, S., Aksehirlioglu, B., Schwörer, A., Uebeler, J., & Eschenhagen, T. (2010) · Circulation Research

Tissue Engineering and Regenerative Medicine3D Printing in Biomedical Research

Cited by 510

MUSCLEMOTION: A Versatile Open Software Tool to Quantify Cardiomyocyte and Cardiac Muscle Contraction In Vitro and In Vivo

Sala, L., van Meer, B. J., Tertoolen, L. G. J., Bakkers, J., Bellin, M., Davis, R. P., Denning, C., Dieben, M. A. E., Eschenhagen, T., Giacomelli, E., et al. (2018) · Circulation Research

Cardiac electrophysiology and arrhythmiasCardiovascular Function and Risk Factors

Cited by 416

Human Engineered Heart Tissue: Analysis of Contractile Force

Mannhardt, I., Breckwoldt, K., Letuffe-Brenière, D., Schaaf, S., Schulz, H., Neuber, C., Benzin, A., Werner, T., Eder, A., Schulze, T., et al. (2016) · Stem Cell Reports

Pluripotent Stem Cells ResearchTissue Engineering and Regenerative Medicine

Cited by 398

Human engineered heart tissue as a versatile tool in basic research and preclinical toxicology

Schaaf, S., Shibamiya, A., Mewe, M., Eder, A., Stöhr, A., Hirt, M. N., Rau, T., Zimmermann, W.-H., Conradi, L., Eschenhagen, T., et al. (2011) · PLoS ONE

Pluripotent Stem Cells ResearchTissue Engineering and Regenerative Medicine

Cited by 365

Differentiation of cardiomyocytes and generation of human engineered heart tissue

Breckwoldt, K., Letuffe-Brenière, D., Mannhardt, I., Schulze, T., Ulmer, B., Werner, T., Benzin, A., Klampe, B., Reinsch, M. C., Laufer, S., et al. (2017) · Nature Protocols

Pluripotent Stem Cells ResearchTissue Engineering and Regenerative Medicine

Cited by 272

SARS-CoV-2 infects and induces cytotoxic effects in human cardiomyocytes

Bojkova, D., Wagner, J. U. G., Shumliakivska, M., Aslan, G. S., Saleem, U., Hansen, A., Luxán, G., Günther, S., Pham, M. D., Krishnan, J., et al. (2020) · Cardiovascular Research

SARS-CoV-2 and COVID-19 ResearchCOVID-19 Clinical Research Studies

Cited by 257

Human engineered heart tissue as a model system for drug testing

Eder, A., Vollert, I., Hansen, A., & Eschenhagen, T. (2016) · Advanced Drug Delivery Reviews

Pluripotent Stem Cells ResearchCardiac electrophysiology and arrhythmias

Cited by 190

Contractile work contributes to maturation of energy metabolism in hiPSC-derived cardiomyocytes

Ulmer, B. M., Stoehr, A., Schulze, M. L., Patel, S., Gucek, M., Mannhardt, I., Funcke, S., Murphy, E., Eschenhagen, T., & Hansen, A. (2018) · Stem Cell Reports

Pluripotent Stem Cells ResearchCongenital heart defects research

Cited by 183

Increased afterload induces pathological cardiac hypertrophy: a new in vitro model

Hirt, M. N., Sörensen, N. A., Bartholdt, L. M., Boeddinghaus, J., Schaaf, S., Eder, A., Vollert, I., Stöhr, A., Schulze, T., Witten, A., et al. (2012) · Basic Research in Cardiology

Cardiac Fibrosis and RemodelingTissue Engineering and Regenerative Medicine

Cited by 154

Automated analysis of contractile force and Ca2+transients in engineered heart tissue

Stoehr, A., Neuber, C., Baldauf, C., Vollert, I., Friedrich, F. W., Flenner, F., Carrier, L., Eder, A., Schaaf, S., Hirt, M. N., et al. (2014) · American Journal of Physiology-Heart and Circulatory Physiology

Cardiac electrophysiology and arrhythmiasTissue Engineering and Regenerative Medicine

Cited by 83

Blinded contractility analysis in hiPSC-cardiomyocytes in engineered heart tissue format: comparison with human atrial trabeculae

Mannhardt, I., Eder, A., Dumotier, B., Prondzynski, M., Krämer, E., Traebert, M., Söhren, K.-D., Flenner, F., Stathopoulou, K., Lemoine, M. D., et al. (2017) · Toxicological Sciences

Pluripotent Stem Cells ResearchCardiac electrophysiology and arrhythmias

Cited by 68