Watson, Philip A.

Development of a second-generation antiandrogen for treatment of advanced prostate cancer.

Tran, C., Ouk, S., Clegg, N. J., Chen, Y., Watson, P. A., Arora, V., Wongvipat, J., Smith-Jones, P. M., Yoo, D., Kwon, A., et al. (2009) · Science

Prostate Cancer Treatment and ResearchHeterocyclic Compound Synthesis and Bioactivity

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Emerging mechanisms of resistance to androgen receptor inhibitors in prostate cancer

Watson, P. A., Arora, V. K., & Sawyers, C. L. (2015) · Nature Reviews Cancer

Prostate Cancer Treatment and ResearchChromatin Remodeling and Cancer

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Constitutively active androgen receptor splice variants expressed in castration-resistant prostate cancer require full-length androgen receptor.

Watson, P. A., Chen, Y. F., Balbas, M. D., Wongvipat, J., Socci, N. D., Viale, A., Kim, K., & Sawyers, C. L. (2010) · Proceedings of the National Academy of Sciences

Prostate Cancer Treatment and ResearchChromatin Remodeling and Cancer

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Overcoming mutation-based resistance to antiandrogens with rational drug design

Balbas, M. D., Evans, M. J., Hosfield, D. J., Wongvipat, J., Arora, V. K., Watson, P. A., Chen, Y., Greene, G. L., Shen, Y., & Sawyers, C. L. (2013) · eLife

Prostate Cancer Treatment and ResearchDrug Transport and Resistance Mechanisms

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Allosteric interactions prime androgen receptor dimerization and activation

Wasmuth, E. V., Broeck, A. V., LaClair, J. R., Hoover, E. A., Lawrence, K. E., Paknejad, N., Pappas, K., Matthies, D., Wang, B., Feng, W., et al. (2022) · Molecular Cell

Prostate Cancer Treatment and ResearchProtein Structure and Dynamics

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