Popko, Brian

Targeted Complement Inhibition at Synapses Prevents Microglial Synaptic Engulfment and Synapse Loss in Demyelinating Disease

Werneburg, S., Jung, J., Kunjamma, R. B., Ha, S.-K., Luciano, N. J., Willis, C. M., Gao, G., Biscola, N. P., Havton, L. A., Crocker, S. J., et al. (2020) · Immunity

Neuroinflammation and Neurodegeneration MechanismsMultiple Sclerosis Research Studies

Cited by 440

Interferon-γ inhibits central nervous system remyelination through a process modulated by endoplasmic reticulum stress

Lin, W., Kemper, A., Dupree, J. L., Harding, H. P., Ron, D., & Popko, B. (2006) · Brain

Multiple Sclerosis Research StudiesNeurogenesis and neuroplasticity mechanisms

Cited by 222

CNS fibroblasts form a fibrotic scar in response to immune cell infiltration.

Dorrier, C. E., Aran, D., Haenelt, E. A., Sheehy, R. N., Hoi, K. K., Pintarić, L., Chen, Y., Lizama, C. O., Cautivo, K. M., Weiner, G. A., et al. (2021) · Nature Neuroscience

Multiple Sclerosis Research StudiesNeuroinflammation and Neurodegeneration Mechanisms

Cited by 199

Oligodendrocyte death results in immune-mediated CNS demyelination

Traka, M., Podojil, J. R., McCarthy, D. P., Miller, S. D., & Popko, B. (2016) · Nature Neuroscience

Multiple Sclerosis Research StudiesT-cell and B-cell Immunology

Cited by 195

Human Apolipoprotein E2, E3, and E4 Isoform-Specific Transgenic Mice: Human-like Pattern of GlialandNeuronal Immunoreactivity in Central Nervous System Not Observed in Wild-Type Mice

Xu, P.-T., Schmechel, D., Rothrock-Christian, T., Burkhart, D. S., Qiu, H.-L., Popko, B., Sullivan, P., Maeda, N., Saunders, A. M., Roses, A. D., et al. (1996) · Neurobiology of Disease

Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 178

Multiscale network modeling of oligodendrocytes reveals molecular components of myelin dysregulation in Alzheimer’s disease

McKenzie, A. T., Moyon, S., Wang, M., Katsyv, I., Song, W.-M., Zhou, X., Dammer, E. B., Duong, D. M., Aaker, J., Zhao, Y., et al. (2017) · Molecular Neurodegeneration

Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 154

Predominant expression of Alzheimer’s disease-associated BIN1 in mature oligodendrocytes and localization to white matter tracts

De Rossi, P., Buggia-Prévot, V., Clayton, B. L. L., Vasquez, J. B., van Sanford, C., Andrew, R. J., Lesnick, R., Botté, A., Deyts, C., Salem, S., et al. (2016) · Molecular Neurodegeneration

Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 151

Oligodendroglial fatty acid metabolism as a central nervous system energy reserve

Asadollahi, E., Trevisiol, A., Saab, A. S., Looser, Z. J., Dibaj, P., Ebrahimi, R., Kusch, K., Ruhwedel, T., Möbius, W., Jahn, O., et al. (2024) · Nature Neuroscience

Lipid metabolism and biosynthesisNeurogenesis and neuroplasticity mechanisms

Cited by 130

A genetic mouse model of adult-onset, pervasive central nervous system demyelination with robust remyelination

Traka, M., Arasi, K., Avila, R. L., Podojil, J. R., Christakos, A., Miller, S. D., Soliven, B., & Popko, B. (2010) · Brain

Multiple Sclerosis Research StudiesNeurogenesis and neuroplasticity mechanisms

Cited by 118

Morphometric analysis of normal, mutant, and transgenic CNS: correlation of myelin basic protein expression to myelinogenesis

Shine, H. D., Readhead, C., Popko, B., Hood, L., & Sidman, R. L. (1992) · Journal of Neurochemistry

Neurogenesis and neuroplasticity mechanismsMultiple Sclerosis Research Studies

Cited by 111

Pharmaceutical integrated stress response enhancement protects oligodendrocytes and provides a potential multiple sclerosis therapeutic

Way, S. W., Podojil, J. R., Clayton, B. L., Zaremba, A., Collins, T. L., Kunjamma, R. B., Robinson, A. P., Brugarolas, P., Miller, R. H., Miller, S. D., et al. (2015) · Nature Communications

Multiple Sclerosis Research StudiesEndoplasmic Reticulum Stress and Disease

Cited by 108

Interferon-γ Protects against Cuprizone-Induced Demyelination

Gao, X., Gillig, T. A., Ye, P., D'Ercole, A. J., Matsushima, G. K., & Popko, B. (2000) · Molecular and Cellular Neuroscience

Multiple Sclerosis Research StudiesNeuroinflammation and Neurodegeneration Mechanisms

Cited by 84

Nur7 Is a Nonsense Mutation in the Mouse Aspartoacylase Gene That Causes Spongy Degeneration of the CNS

Traka, M., Wollmann, R. L., Cerda, S. R., Dugas, J., Barres, B. A., & Popko, B. (2008) · The Journal of Neuroscience

Metabolism and Genetic DisordersLysosomal Storage Disorders Research

Cited by 82

Absence of oligodendroglial glucosylceramide synthesis does not result in CNS myelin abnormalities or alter the dysmyelinating phenotype of CGT‐deficient mice

Saadat, L., Dupree, J. L., Kilkus, J., Han, X., Traka, M., Proia, R. L., Dawson, G., & Popko, B. (2010) · Glia

Lysosomal Storage Disorders ResearchSphingolipid Metabolism and Signaling

Cited by 61