Shearer, Todd W.

Discovery, synthesis, and biological evaluation of thiazoloquin(az)olin(on)es as potent CD38 inhibitors

Haffner, C. D., Becherer, J. D., Boros, E. E., Cadilla, R., Carpenter, T., Cowan, D., Deaton, D. N., Guo, Y., Harrington, W., Henke, B. R., et al. (2015) · Journal of Medicinal Chemistry

Sirtuins and Resveratrol in MedicineHeterocyclic Compound Synthesis and Bioactivity

Cited by 137

Identification and Characterization of 4-Chloro-N-(2-{[5-trifluoromethyl)-2-pyridyl]sulfonyl}ethyl)benzamide (GSK3787), a Selective and Irreversible Peroxisome Proliferator-Activated Receptor δ (PPARδ) Antagonist

Shearer, B. G., Wiethe, R. W., Ashe, A., Billin, A. N., Way, J. M., Stanley, T. B., Wagner, C. D., Xu, R. X., Leesnitzer, L. M., Merrihew, R. V., et al. (2010) · Journal of Medicinal Chemistry

Peroxisome Proliferator-Activated ReceptorsComputational Drug Discovery Methods

Cited by 78

Total-body creatine pool size and skeletal muscle mass determination by creatine-(methyl-d3) dilution in rats

Stimpson, S. A., Turner, S. M., Clifton, L. G., Poole, J. C., Mohammed, H. A., Shearer, T. W., Waitt, G. M., Hagerty, L. L., Remlinger, K. S., Hellerstein, M. K., et al. (2012) · Journal of Applied Physiology

Muscle metabolism and nutritionNutrition and Health in Aging

Cited by 73

Longitudinal changes in total body creatine pool size and skeletal muscle mass using the D3‐creatine dilution method

Stimpson, S. A., Leonard, M. S., Clifton, L. G., Poole, J. C., Turner, S. M., Shearer, T. W., Remlinger, K. S., Clark, R. V., Hellerstein, M. K., & Evans, W. J. (2013) · Journal of Cachexia Sarcopenia and Muscle

Muscle metabolism and nutritionNutrition and Health in Aging

Cited by 59

Discovery of 4-amino-8-quinoline carboxamides as novel, submicromolar inhibitors of NAD-hydrolyzing enzyme CD38

Becherer, J. D., Boros, E. E., Carpenter, T. Y., Cowan, D. J., Deaton, D. N., Haffner, C. D., Jeune, M. R., Kaldor, I. W., Poole, J. C., Preugschat, F., et al. (2015) · Journal of Medicinal Chemistry

Sirtuins and Resveratrol in MedicineBiochemical and Molecular Research

Cited by 55