Schaeffer, David F.

Transcription phenotypes of pancreatic cancer are driven by genomic events during tumor evolution

Chan-Seng-Yue, M., Kim, J. C., Wilson, G. W., Ng, K., Figueroa, E. F., O’Kane, G. M., Connor, A. A., Denroche, R. E., Grant, R. C., McLeod, J., et al. (2020) · Nature Genetics

Pancreatic and Hepatic Oncology ResearchCancer Genomics and Diagnostics

Cited by 669

Cell of origin affects tumour development and phenotype in pancreatic ductal adenocarcinoma

Lee, A. Y. L., Dubois, C. L., Sarai, K., Zarei, S., Schaeffer, D. F., Sander, M., & Kopp, J. L. (2019) · Gut

Pancreatic and Hepatic Oncology ResearchCancer Genomics and Diagnostics

Cited by 139

Overcoming Adaptive Resistance to KRAS and MEK Inhibitors by Co-targeting mTORC1/2 Complexes in Pancreatic Cancer

Brown, W. S., McDonald, P. C., Nemirovsky, O., Awrey, S., Chafe, S. C., Schaeffer, D. F., Li, J., Renouf, D. J., Stanger, B. Z., & Dedhar, S. (2020) · Cell Reports Medicine

PI3K/AKT/mTOR signaling in cancerPancreatic and Hepatic Oncology Research

Cited by 111

An international consensus to standardize integration of histopathology in ulcerative colitis clinical trials

Ma, C., Sedano, R., Almradi, A., Vande Casteele, N., Parker, C. E., Guizzetti, L., Schaeffer, D. F., Riddell, R. H., Pai, R. K., Battat, R., et al. (2021) · Gastroenterology

Inflammatory Bowel DiseaseMicroscopic Colitis

Cited by 105

Loss of Pten and activation of kras synergistically induce formation of intraductal papillary mucinous neoplasia from pancreatic ductal cells in mice

Kopp, J. L., Dubois, C. L., Schaeffer, D. F., Samani, A., Taghizadeh, F., Cowan, R. W., Rhim, A. D., Stiles, B. L., Valasek, M., & Sander, M. (2018) · Gastroenterology

Pancreatic and Hepatic Oncology ResearchPancreatic function and diabetes

Cited by 80

An expert consensus to standardise the assessment of histological disease activity in Crohn's disease clinical trials

Almradi, A., Ma, C., D'Haens, G. R., Sandborn, W. J., Parker, C. E., Guizzetti, L., Borralho Nunes, P., De Hertogh, G., Feakins, R. M., Khanna, R., et al. (2021) · Alimentary Pharmacology & Therapeutics

Inflammatory Bowel DiseaseOcular Diseases and Behçet’s Syndrome

Cited by 34