Koper, Jan W.

A polymorphism in the glucocorticoid receptor gene, which decreases sensitivity to glucocorticoids in vivo, is associated with low insulin and cholesterol levels

van Rossum, E. F. C., Koper, J. W., Huizenga, N. A. T. M., Uitterlinden, A. G., Janssen, J. A. M. J. L., Brinkmann, A. O., Grobbee, D. E., de Jong, F. H., van Duyn, C. M., Pols, H. A. P., et al. (2002) · Diabetes

Adrenal Hormones and DisordersStress Responses and Cortisol

Cited by 329

Glucocorticoid sensitivity in health and disease

Quax, R. A., Manenschijn, L., Koper, J. W., Hazes, J. M., Lamberts, S. W. J., van Rossum, E. F. C., & Feelders, R. A. (2013) · Nature Reviews Endocrinology

Estrogen and related hormone effectsAdrenal Hormones and Disorders

Cited by 310

The ER22/23EK polymorphism in the glucocorticoid receptor gene is associated with a beneficial body composition and muscle strength in young adults

van Rossum, E. F. C., Voorhoeve, P. G., te Velde, S. J., Koper, J. W., Delemarre-van de Waal, H. A., Kemper, H. C. G., & Lamberts, S. W. J. (2004) · The Journal of Clinical Endocrinology & Metabolism

Genetics and Physical PerformanceGenetic Associations and Epidemiology

Cited by 164

Differential inhibition of 17α-hydroxylase and 17,20 lyase activities by three novel missense CYP17 mutations identified in patients with P450c17 deficiency

van den Akker, E. L. T., Koper, J. W., Boehmer, A. L. M., Themmen, A. P. N., Verhoef-Post, M., Timmerman, M. A., Otten, B. J., Drop, S. L. S., & De Jong, F. H. (2002) · The Journal of Clinical Endocrinology & Metabolism

Sexual Differentiation and DisordersAdrenal Hormones and Disorders

Cited by 125

A novel tool in the diagnosis and follow-up of (cyclic) Cushing's syndrome: measurement of long-term cortisol in scalp hair

Manenschijn, L., Koper, J. W., van den Akker, E. L. T., de Heide, L. J. M., Geerdink, E. A. M., de Jong, F. H., Feelders, R. A., & van Rossum, E. F. C. (2012) · The Journal of Clinical Endocrinology & Metabolism

Pituitary Gland Disorders and TreatmentsAdrenal Hormones and Disorders

Cited by 122

Expression in hematological malignancies of a glucocorticoid receptor splice variant that augments glucocorticoid receptor-mediated effects in transfected cells

de Lange, P., Segeren, C. M., Koper, J. W., Wiemer, E., Sonneveld, P., Brinkmann, A. O., White, A., Brogan, I. J., de Jong, F. H., & Lamberts, S. W. J. (2010) · Cancer Research

Estrogen and related hormone effectsRNA Research and Splicing

Cited by 121

Clinical aspects of glucocorticoid sensitivity

Lamberts, S. W. J., Huizenga, A. T. M., de Lange, P., de Jong, F. H., & Koper, J. W. (1996) · Steroids

Adrenal Hormones and DisordersEstrogen and related hormone effects

Cited by 99

Glucocorticoid receptor polymorphisms and haplotypes and their expression in health and disease

Koper, J. W., van Rossum, E. F. C., & van den Akker, E. L. T. (2014) · Steroids

Genetic Associations and EpidemiologyEstrogen and related hormone effects

Cited by 97

Hair cortisol and cortisone are decreased by natural sunlight

Wester, V. L., van der Wulp, N. R. P., Koper, J. W., de Rijke, Y. B., & van Rossum, E. F. C. (2016) · Psychoneuroendocrinology

Stress Responses and CortisolAdrenal Hormones and Disorders

Cited by 93

Glucocorticoid receptor mRNA levels are selectively decreased in neutrophils of children with sepsis

van den Akker, E. L. T., Koper, J. W., Joosten, K., de Jong, F. H., Hazelzet, J. A., Lamberts, S. W. J., & Hokken-Koelega, A. C. S. (2009) · Intensive Care Medicine

Adrenal Hormones and DisordersSepsis Diagnosis and Treatment

Cited by 81

Strategies for the Characterization of Disorders in Cortisol Sensitivity

Russcher, H., Smit, P., van Rossum, E. F. C., van den Akker, E. L. T., Brinkmann, A. O., de Heide, L. J. M., de Jong, F. H., Koper, J. W., & Lamberts, S. W. J. (2006) · The Journal of Clinical Endocrinology & Metabolism

Adrenal Hormones and DisordersEstrogen and related hormone effects

Cited by 43

Scalp hair cortisol for diagnosis of Cushing's syndrome

Wester, V. L., Reincke, M., Koper, J. W., van den Akker, E. L. T., Manenschijn, L., Berr, C. M., Fazel, J., de Rijke, Y. B., Feelders, R. A., & van Rossum, E. F. C. (2017) · European Journal of Endocrinology

Pituitary Gland Disorders and TreatmentsAdrenal Hormones and Disorders

Cited by 39

Tissue mRNA expression of the glucocorticoid receptor and its splice variants in fatal critical illness

Peeters, R. P., Hagendorf, A., Vanhorebeek, I., Visser, T. J., Klootwijk, W., Mesotten, D., Wouters, P. J., Koper, J. W., De Jong, F. H., Feelders, R. A., et al. (2009) · Clinical Endocrinology

Adrenal Hormones and DisordersHyperglycemia and glycemic control in critically ill and hospitalized patients

Cited by 36

Functional polymorphism of the glucocorticoid receptor gene associates with mania and hypomania in bipolar disorder

Spijker, A. T., Van Rossum, E. F. C., Hoencamp, E., DeRijk, R. H., Haffmans, J., Blom, M., Manenschijn, L., Koper, J. W., Lamberts, S. W., & Zitman, F. G. (2009) · Bipolar Disorders

Bipolar Disorder and TreatmentSchizophrenia research and treatment

Cited by 36

Glucocorticoid receptor haplotype and metabolic syndrome: the Lifelines cohort study

Wester, V. L., Koper, J. W., van den Akker, E. L. T., Franco, O. H., Stolk, R. P., & van Rossum, E. F. C. (2016) · European Journal of Endocrinology

Genetic Associations and EpidemiologyAdrenal Hormones and Disorders

Cited by 24

Anthropometrics and Metabolic Syndrome in Relation to Glucocorticoid Receptor Polymorphisms in Corticosteroid Users

Savas, M., Wester, V. L., van der Voorn, B., Iyer, A. M., Koper, J. W., van den Akker, E. L. T., & van Rossum, E. F. C. (2021) · Neuroendocrinology

Adrenal Hormones and DisordersGenetic Associations and Epidemiology

Cited by 13