Donehower, Lawrence A.

Does p53 affect organismal aging?

Donehower, L. A. (2002) · Journal of Cellular Physiology

Genetics, Aging, and Longevity in Model OrganismsTelomeres, Telomerase, and Senescence

Cited by 155

Integrated analysis of TP53 gene and pathway alterations in the cancer genome atlas

Donehower, L. A., Soussi, T., Korkut, A., Liu, Y., Schultz, A., Cardenas, M., Li, X., Babur, O., Hsu, T.-K., Lichtarge, O., et al. (2019) · Cell Reports

Cancer-related Molecular PathwaysCancer Genomics and Diagnostics

Cited by 150

NKD2, a negative regulator of Wnt signaling, suppresses tumor growth and metastasis in osteosarcoma

Zhao, S., Kurenbekova, L., Gao, Y., Roos, A., Creighton, C. J., Rao, P., Hicks, J., Man, T.-K., Lau, C., Brown, A. M. C., et al. (2015) · Oncogene

Sarcoma Diagnosis and TreatmentWnt/β-catenin signaling in development and cancer

Cited by 139

Mdm2–p53 signaling regulates epidermal stem cell senescence and premature aging phenotypes in mouse skin

Gannon, H. S., Donehower, L. A., Lyle, S., & Jones, S. N. (2011) · Developmental Biology

Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms

Cited by 87

Exercise effects on tumorigenesis in a p53-deficient mouse model of breast cancer

COLBERT, L. H., WESTERLIND, K. C., PERKINS, S. N., HAINES, D. C., BERRIGAN, D., DONEHOWER, L. A., FUCHS-YOUNG, R., & HURSTING, S. D. (2009) · Medicine & Science in Sports & Exercise

Cancer Risks and FactorsMetabolism, Diabetes, and Cancer

Cited by 60

Cooperativity of p19ARF, Mdm2, and p53 in murine tumorigenesis

Moore, L., Venkatachalam, S., Vogel, H., Watt, J. C., Wu, C.-L., Steinman, H., Jones, S. N., & Donehower, L. A. (2003) · Oncogene

Cancer-related Molecular PathwaysHeat shock proteins research

Cited by 48

The Wip1 phosphatase and Mdm2: cracking the “Wip” on p53 stability

Lu, X., Nguyen, T.-A., Zhang, X., & Donehower, L. A. (2008) · Cell Cycle

Cancer-related Molecular PathwaysProtein Tyrosine Phosphatases

Cited by 44