De, Bishnu P.

AAVrh.10-Mediated APOE2 Central Nervous System Gene Therapy for APOE4-Associated Alzheimer's Disease

Rosenberg, J. B., Kaplitt, M. G., De, B. P., Chen, A., Flagiello, T., Salami, C., Pey, E., Zhao, L., Ricart Arbona, R. J., Monette, S., et al. (2018) · Human Gene Therapy Clinical Development

Virus-based gene therapy researchAlzheimer's disease research and treatments

Cited by 176

High levels of persistent expression of α1-antitrypsin mediated by the nonhuman primate serotype rh. 10 adeno-associated virus despite preexisting immunity to common human adeno-associated viruses

De, B. P., Heguy, A., Hackett, N. R., Ferris, B., Leopold, P. L., Lee, J., Pierre, L., Gao, G., Wilson, J. M., & Crystal, R. G. (2006) · Molecular Therapy

Virus-based gene therapy researchRNA Interference and Gene Delivery

Cited by 129

Impaired Innate Host Defense Causes Susceptibility to Respiratory Virus Infections in Cystic Fibrosis

Zheng, S., De, B. P., Choudhary, S., Comhair, S. A. A., Goggans, T., Slee, R., Williams, B. R. G., Pilewski, J., Haque, S. J., & Erzurum, S. C. (2003) · Immunity

Cystic Fibrosis Research Advancesinterferon and immune responses

Cited by 125

Smoking accelerates aging of the small airway epithelium

Walters, M. S., De, B. P., Salit, J., Buro-Auriemma, L. J., Wilson, T., Rogalski, A. M., Lief, L., Hackett, N. R., Staudt, M. R., Tilley, A. E., et al. (2014) · Respiratory Research

Smoking Behavior and CessationTelomeres, Telomerase, and Senescence

Cited by 87

Slowing late infantile Batten disease by direct brain parenchymal administration of a rh.10 adeno-associated virus expressing CLN2

Sondhi, D., Kaminsky, S. M., Hackett, N. R., Pagovich, O. E., Rosenberg, J. B., De, B. P., Chen, A., Van de Graaf, B., Mezey, J. G., Mammen, G. W., et al. (2020) · Science Translational Medicine

Lysosomal Storage Disorders ResearchVirus-based gene therapy research

Cited by 72

Comparative Efficacy and Safety of Multiple Routes of Direct CNS Administration of Adeno-Associated Virus Gene Transfer Vector Serotype rh.10 Expressing the Human Arylsulfatase A cDNA to Nonhuman Primates

Rosenberg, J. B., Sondhi, D., Rubin, D. G., Monette, S., Chen, A., Cram, S., De, B. P., Kaminsky, S. M., Sevin, C., Aubourg, P., et al. (2014) · Human Gene Therapy Clinical Development

Virus-based gene therapy researchLysosomal Storage Disorders Research

Cited by 58

Genetic delivery of an anti-RSV antibody to protect against pulmonary infection with RSV

Skaricic, D., Traube, C., De, B., Joh, J., Boyer, J., Crystal, R. G., & Worgall, S. (2008) · Virology

Virus-based gene therapy researchRespiratory viral infections research

Cited by 54

Biology of the Adrenal Gland Cortex Obviates Effective Use of Adeno-Associated Virus Vectors to Treat Hereditary Adrenal Disorders

Markmann, S., De, B. P., Reid, J., Jose, C. L., Rosenberg, J. B., Leopold, P. L., Kaminsky, S. M., Sondhi, D., Pagovich, O., & Crystal, R. G. (2018) · Human Gene Therapy

Virus-based gene therapy researchAdrenal Hormones and Disorders

Cited by 42

Safety of Direct Intraparenchymal AAVrh.10-Mediated Central Nervous System Gene Therapy for Metachromatic Leukodystrophy

Rosenberg, J. B., Chen, A., De, B. P., Dyke, J. P., Ballon, D. J., Monette, S., Ricart Arbona, R. J., Kaminsky, S. M., Crystal, R. G., & Sondhi, D. (2021) · Human Gene Therapy

Virus-based gene therapy researchLysosomal Storage Disorders Research

Cited by 41

Genetic Modification of the Lung Directed Toward Treatment of Human Disease

Sondhi, D., Stiles, K. M., De, B. P., & Crystal, R. G. (2017) · Human Gene Therapy

Virus-based gene therapy researchRNA Interference and Gene Delivery

Cited by 36

365. Long-Term Toxicology Evaluation of AAVrh. 10hARSA Administration to the CNS of Nonhuman Primates to Treat Metachromatic Leukodystrophy

Sondhi, D., Rosenberg, J. B., De, B. P., Monette, S., Chen, A., Flagiello, T., Caffrey, E., Kaminsky, S. M., Aubourg, P., & Crystal, R. G. (2016) · Molecular Therapy

Lysosomal Storage Disorders ResearchVirus-based gene therapy research

Cited by 3