Maeda, Nobuyo

Spontaneous Hypercholesterolemia and Arterial Lesions in Mice Lacking Apolipoprotein E

Zhang, S. H., Reddick, R. L., Piedrahita, J. A., & Maeda, N. (1992) · Science

Cholesterol and Lipid MetabolismAtherosclerosis and Cardiovascular Diseases

Cited by 2,237

Targeted Replacement of the Mouse Apolipoprotein E Gene with the Common Human APOE3 Allele Enhances Diet-induced Hypercholesterolemia and Atherosclerosis

Sullivan, P. M., Mezdour, H., Aratani, Y., Knouff, C., Najib, J., Reddick, R. L., Quarfordt, S. H., & Maeda, N. (1997) · Journal of Biological Chemistry

Cholesterol and Lipid MetabolismLipoproteins and Cardiovascular Health

Cited by 575

Targeted inactivation of hepatic Abca1 causes profound hypoalphalipoproteinemia and kidney hypercatabolism of apoA-I

Timmins, J. M., Lee, J.-Y., Boudyguina, E., Kluckman, K. D., Brunham, L. R., Mulya, A., Gebre, A. K., Coutinho, J. M., Colvin, P. L., Smith, T. L., et al. (2005) · Journal of Clinical Investigation

Cholesterol and Lipid MetabolismLipid metabolism and disorders

Cited by 447

Hepatocellular and hepatic peroxisomal alterations in mice with a disrupted peroxisomal fatty acyl-coenzyme A oxidase gene

Fan, C.-Y., Pan, J., Chu, R., Lee, D., Kluckman, K. D., Usuda, N., Singh, I., Yeldandi, A. V., Rao, M. S., Maeda, N., et al. (1996) · Journal of Biological Chemistry

Metabolism and Genetic DisordersPeroxisome Proliferator-Activated Receptors

Cited by 268

Aortic wall damage in mice unable to synthesize ascorbic acid

Maeda, N., Hagihara, H., Nakata, Y., Hiller, S., Wilder, J., & Reddick, R. (2000) · Proceedings of the National Academy of Sciences

Vitamin C and Antioxidants ResearchAntioxidant Activity and Oxidative Stress

Cited by 260

Early diet-induced non-alcoholic steatohepatitis in APOE2 knock-in mice and its prevention by fibrates

Shiri-Sverdlov, R., Wouters, K., Gorp, P. J. V., Gijbels, M. J., Noel, B., Buffat, L., Staels, B., Maeda, N., Bilsen, M. V., & Hofker, M. H. (2006) · Journal of Hepatology

Liver Disease Diagnosis and TreatmentLiver physiology and pathology

Cited by 241

Human Apolipoprotein E2, E3, and E4 Isoform-Specific Transgenic Mice: Human-like Pattern of GlialandNeuronal Immunoreactivity in Central Nervous System Not Observed in Wild-Type Mice

Xu, P.-T., Schmechel, D., Rothrock-Christian, T., Burkhart, D. S., Qiu, H.-L., Popko, B., Sullivan, P., Maeda, N., Saunders, A. M., Roses, A. D., et al. (1996) · Neurobiology of Disease

Alzheimer's disease research and treatmentsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 178

The sodium-dependent ascorbic acid transporter family SLC23

Bürzle, M., Suzuki, Y., Ackermann, D., Miyazaki, H., Maeda, N., Clémençon, B., Burrier, R., & Hediger, M. A. (2013) · Molecular Aspects of Medicine

Vitamin C and Antioxidants ResearchAmino Acid Enzymes and Metabolism

Cited by 158

Apolipoprotein E knock-out and knock-in mice: atherosclerosis, metabolic syndrome, and beyond

Pendse, A. A., Arbones-Mainar, J. M., Johnson, L. A., Altenburg, M. K., & Maeda, N. (2009) · Journal of Lipid Research

Cholesterol and Lipid MetabolismAtherosclerosis and Cardiovascular Diseases

Cited by 155

Human apoE4-targeted replacement mice display synaptic deficits in the absence of neuropathology.

Wang, C., Wilson, W. A., Moore, S. D., Mace, B. E., Maeda, N., Schmechel, D. E., & Sullivan, P. M. (2005) · Neurobiology of Disease

Alzheimer's disease research and treatmentsNeuroscience and Neuropharmacology Research

Cited by 138

α-Lipoic Acid Prevents the Increase in Atherosclerosis Induced by Diabetes in Apolipoprotein E–Deficient Mice Fed High-Fat/Low-Cholesterol Diet

Yi, X., & Maeda, N. (2006) · Diabetes

Biochemical Acid Research StudiesAntioxidant Activity and Oxidative Stress

Cited by 117

Hepatic Lipase Deficiency Increases Plasma Cholesterol but Reduces Susceptibility to Atherosclerosis in Apolipoprotein E-deficient Mice

Mezdour, H., Jones, R., Dengremont, C., Castro, G., & Maeda, N. (1997) · Journal of Biological Chemistry

Lipid metabolism and disordersCholesterol and Lipid Metabolism

Cited by 113

Apolipoprotein E–low density lipoprotein receptor interaction affects spatial memory retention and brain ApoE levels in an isoform-dependent manner

Johnson, L. A., Olsen, R. H. J., Merkens, L. S., DeBarber, A., Steiner, R. D., Sullivan, P. M., Maeda, N., & Raber, J. (2014) · Neurobiology of Disease

Alzheimer's disease research and treatmentsCholesterol and Lipid Metabolism

Cited by 107

Vasodilator mechanisms in the coronary circulation of endothelial nitric oxide synthase-deficient mice

Lamping, K. G., Nuno, D. W., Shesely, E. G., Maeda, N., & Faraci, F. M. (2000) · American Journal of Physiology-Heart and Circulatory Physiology

Nitric Oxide and Endothelin EffectsCardiovascular Health and Disease Prevention

Cited by 99

Ascorbic acid-independent synthesis of collagen in mice

Parsons, K. K., Maeda, N., Yamauchi, M., Banes, A. J., & Koller, B. H. (2006) · American Journal of Physiology-Endocrinology and Metabolism

Vitamin C and Antioxidants ResearchMicrobial metabolism and enzyme function

Cited by 69

Contribution of the myeloperoxidase-dependent oxidative system to host defence against Cryptococcus neoformans

Aratani, Y., Kura, F., Watanabe, H., Akagawa, H., Takano, Y., Ishida-Okawara, A., Suzuki, K., Maeda, N., & Koyama, H. (2006) · Journal of Medical Microbiology

Fungal Infections and StudiesNeutrophil, Myeloperoxidase and Oxidative Mechanisms

Cited by 65

Vitamin C fails to protect amino acids and lipids from oxidation during acute inflammation

Gaut, J. P., Belaaouaj, A., Byun, J., Roberts, L. J., Maeda, N., Frei, B., & Heinecke, J. W. (2006) · Free Radical Biology and Medicine

Vitamin C and Antioxidants ResearchAntioxidant Activity and Oxidative Stress

Cited by 48