Shibasaki, Tadao

GLP-1 receptor activation and epac2 link atrial natriuretic peptide secretion to control of blood pressure

Kim, M., Platt, M. J., Shibasaki, T., Quaggin, S. E., Backx, P. H., Seino, S., Simpson, J. A., & Drucker, D. J. (2013) · Nature Medicine

Diabetes Treatment and ManagementBlood Pressure and Hypertension Studies

Cited by 514

cAMP-GEFII is a direct target of cAMP in regulated exocytosis

Ozaki, N., Shibasaki, T., Kashima, Y., Miki, T., Takahashi, K., Ueno, H., Sunaga, Y., Yano, H., Matsuura, Y., Iwanaga, T., et al. (2000) · Nature Cell Biology

Cellular transport and secretionProtein Kinase Regulation and GTPase Signaling

Cited by 481

Essential role of Epac2/Rap1 signaling in regulation of insulin granule dynamics by cAMP

Shibasaki, T., Takahashi, H., Miki, T., Sunaga, Y., Matsumura, K., Yamanaka, M., Zhang, C., Tamamoto, A., Satoh, T., Miyazaki, J.-I., et al. (2007) · Proceedings of the National Academy of Sciences

Pancreatic function and diabetesCellular transport and secretion

Cited by 425

Dynamics of insulin secretion and the clinical implications for obesity and diabetes

Seino, S., Shibasaki, T., & Minami, K. (2011) · Journal of Clinical Investigation

Pancreatic function and diabetesDiabetes and associated disorders

Cited by 364

GLP-1 Inhibits and Adrenaline Stimulates Glucagon Release by Differential Modulation of N- and L-Type Ca2+ Channel-Dependent Exocytosis

De Marinis, Y. Z., Salehi, A., Ward, C. E., Zhang, Q., Abdulkader, F., Bengtsson, M., Braha, O., Braun, M., Ramracheya, R., Amisten, S., et al. (2010) · Cell Metabolism

Pancreatic function and diabetesDiabetes Treatment and Management

Cited by 257

Glutamate Acts as a Key Signal Linking Glucose Metabolism to Incretin/cAMP Action to Amplify Insulin Secretion

Gheni, G., Ogura, M., Iwasaki, M., Yokoi, N., Minami, K., Nakayama, Y., Harada, K., Hastoy, B., Wu, X., Takahashi, H., et al. (2014) · Cell Reports

Pancreatic function and diabetesDiabetes Treatment and Management

Cited by 156

Rim2α Determines Docking and Priming States in Insulin Granule Exocytosis

Yasuda, T., Shibasaki, T., Minami, K., Takahashi, H., Mizoguchi, A., Uriu, Y., Numata, T., Mori, Y., Miyazaki, J.-I., Miki, T., et al. (2010) · Cell Metabolism

Cellular transport and secretionPancreatic function and diabetes

Cited by 110