Loeffler, Jay S.
Harvard University · Massachusetts General Hospital · Center for Systems Biology
12 papers on CoChat
Most cited papers
- Verified
AZD2171, a Pan-VEGF Receptor Tyrosine Kinase Inhibitor, Normalizes Tumor Vasculature and Alleviates Edema in Glioblastoma Patients
Batchelor, T. T., Sorensen, A. G., di Tomaso, E., Zhang, W.-T., Duda, D. G., Cohen, K. S., Kozak, K. R., Cahill, D. P., Chen, P.-J., Zhu, M., et al. (2007) · Cancer Cell
Angiogenesis and VEGF in CancerGlioma Diagnosis and Treatment
Cited by 1,769
- Verified
Biomarkers of response and resistance to antiangiogenic therapy
Jain, R. K., Duda, D. G., Willett, C. G., Sahani, D. V., Zhu, A. X., Loeffler, J. S., Batchelor, T. T., & Sorensen, A. G. (2009) · Nature Reviews Clinical Oncology
Angiogenesis and VEGF in CancerColorectal Cancer Treatments and Studies
Cited by 572
- Verified
The biology of brain metastases—translation to new therapies
Eichler, A. F., Chung, E., Kodack, D. P., Loeffler, J. S., Fukumura, D., & Jain, R. K. (2011) · Nature Reviews Clinical Oncology
Brain Metastases and TreatmentGlioma Diagnosis and Treatment
Cited by 567
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Phase II Study of Cediranib, an Oral Pan–Vascular Endothelial Growth Factor Receptor Tyrosine Kinase Inhibitor, in Patients With Recurrent Glioblastoma
Batchelor, T. T., Duda, D. G., di Tomaso, E., Ancukiewicz, M., Plotkin, S. R., Gerstner, E., Eichler, A. F., Drappatz, J., Hochberg, F. H., Benner, T., et al. (2010) · Journal of Clinical Oncology
Glioma Diagnosis and TreatmentAngiogenesis and VEGF in Cancer
Cited by 520
- Verified
Single-nucleus and spatial transcriptome profiling of pancreatic cancer identifies multicellular dynamics associated with neoadjuvant treatment
Hwang, W. L., Jagadeesh, K. A., Guo, J. A., Hoffman, H. I., Yadollahpour, P., Reeves, J. W., Mohan, R., Drokhlyansky, E., Van Wittenberghe, N., Ashenberg, O., et al. (2022) · Nature Genetics
Pancreatic and Hepatic Oncology ResearchSingle-cell and spatial transcriptomics
Cited by 426
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The prognostic significance of phosphatidylinositol 3-kinase pathway activation in human gliomas
Chakravarti, A., Zhai, G., Suzuki, Y., Sarkesh, S., Black, P. M., Muzikansky, A., & Loeffler, J. S. (2004) · Journal of Clinical Oncology
Glioma Diagnosis and TreatmentPI3K/AKT/mTOR signaling in cancer
Cited by 377
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Assessing the interactions between radiotherapy and antitumour immunity
Grassberger, C., Ellsworth, S. G., Wilks, M. Q., Keane, F. K., & Loeffler, J. S. (2019) · Nature Reviews Clinical Oncology
Cancer Immunotherapy and BiomarkersImmunotherapy and Immune Responses
Cited by 244
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Lessons From Anti–Vascular Endothelial Growth Factor and Anti–Vascular Endothelial Growth Factor Receptor Trials in Patients With Glioblastoma
Lu-Emerson, C., Duda, D. G., Emblem, K. E., Taylor, J. W., Gerstner, E. R., Loeffler, J. S., Batchelor, T. T., & Jain, R. K. (2015) · Journal of Clinical Oncology
Glioma Diagnosis and TreatmentAngiogenesis and VEGF in Cancer
Cited by 179
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Outcomes of proton therapy for patients with functional pituitary adenomas
Wattson, D. A., Tanguturi, S. K., Spiegel, D. Y., Niemierko, A., Biller, B. M. K., Nachtigall, L. B., Bussière, M. R., Swearingen, B., Chapman, P. H., Loeffler, J. S., et al. (2014) · International Journal of Radiation Oncology*Biology*Physics
Pituitary Gland Disorders and TreatmentsRadiation Therapy and Dosimetry
Cited by 125
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Significance of targeted therapy and genetic alterations in EGFR, ALK, or KRAS on survival in patients with non-small cell lung cancer treated with radiotherapy for brain metastases
Mak, K. S., Gainor, J. F., Niemierko, A., Oh, K. S., Willers, H., Choi, N. C., Loeffler, J. S., Sequist, L. V., Shaw, A. T., & Shih, H. A. (2015) · Neuro-Oncology
Lung Cancer Treatments and MutationsBrain Metastases and Treatment
Cited by 83
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Growth Hormone Deficiency Is Associated with Decreased Quality of Life in Patients with Prior Acromegaly
Wexler, T., Gunnell, L., Omer, Z., Kuhlthau, K., Beauregard, C., Graham, G., Utz, A. L., Biller, B., Nachtigall, L., Loeffler, J., et al. (2009) · The Journal of Clinical Endocrinology & Metabolism
Pituitary Gland Disorders and TreatmentsGrowth Hormone and Insulin-like Growth Factors
Cited by 69
- Verified
Growth hormone deficiency after treatment of acromegaly: a randomized, placebo-controlled study of growth hormone replacement
Miller, K. K., Wexler, T., Fazeli, P., Gunnell, L., Graham, G. J., Beauregard, C., Hemphill, L., Nachtigall, L., Loeffler, J., Swearingen, B., et al. (2010) · The Journal of Clinical Endocrinology & Metabolism
Growth Hormone and Insulin-like Growth FactorsPituitary Gland Disorders and Treatments
Cited by 66
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