Ballard, Theresa M.

Chronic Pharmacological mGlu5 Inhibition Corrects Fragile X in Adult Mice

Michalon, A., Sidorov, M., Ballard, T. M., Ozmen, L., Spooren, W., Wettstein, J. G., Jaeschke, G., Bear, M. F., & Lindemann, L. (2012) · Neuron

Genetics and Neurodevelopmental DisordersNeuroscience and Neuropharmacology Research

Cited by 489

Fenobam: A Clinically Validated Nonbenzodiazepine Anxiolytic Is a Potent, Selective, and Noncompetitive mGlu5 Receptor Antagonist with Inverse Agonist Activity

Porter, R. H. P., Jaeschke, G., Spooren, W., Ballard, T. M., Büttelmann, B., Kolczewski, S., Peters, J.-U., Prinssen, E., Wichmann, J., Vieira, E., et al. (2005) · The Journal of Pharmacology and Experimental Therapeutics

Neuroscience and Neuropharmacology ResearchReceptor Mechanisms and Signaling

Cited by 308

Drug targets for cognitive enhancement in neuropsychiatric disorders.

Wallace, T. L., Ballard, T. M., Pouzet, B., Riedel, W. J., & Wettstein, J. G. (2011) · Pharmacology Biochemistry and Behavior

Neuroscience and Neuropharmacology ResearchCholinesterase and Neurodegenerative Diseases

Cited by 127

Phosphorylation of Tau at S422 is enhanced by Aβ in TauPS2APP triple transgenic mice

Grueninger, F., Bohrmann, B., Czech, C., Ballard, T. M., Frey, J. R., Weidensteiner, C., von Kienlin, M., & Ozmen, L. (2010) · Neurobiology of Disease

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 117

Cognitive impairment in major depression and the mGlu2 receptor as a therapeutic target

Goeldner, C., Ballard, T. M., Knoflach, F., Wichmann, J., Gatti, S., & Umbricht, D. (2013) · Neuropharmacology

Treatment of Major DepressionNeuroscience and Neuropharmacology Research

Cited by 96

Failed trials for central nervous system disorders do not necessarily invalidate preclinical models and drug targets

Bespalov, A., Steckler, T., Altevogt, B., Koustova, E., Skolnick, P., Deaver, D., Millan, M. J., Bastlund, J. F., Doller, D., Witkin, J., et al. (2016) · Nature Reviews Drug Discovery

Animal testing and alternativesComputational Drug Discovery Methods

Cited by 84

Chronic Metabotropic Glutamate Receptor 5 Inhibition Corrects Local Alterations of Brain Activity and Improves Cognitive Performance in Fragile X Mice

Michalon, A., Bruns, A., Risterucci, C., Honer, M., Ballard, T. M., Ozmen, L., Jaeschke, G., Wettstein, J. G., von Kienlin, M., Künnecke, B., et al. (2014) · Biological Psychiatry

Genetics and Neurodevelopmental DisordersNeuroscience and Neuropharmacology Research

Cited by 67

The subchronic phencyclidine rat model: relevance for the assessment of novel therapeutics for cognitive impairment associated with schizophrenia

Janhunen, S. K., Svärd, H., Talpos, J., Kumar, G., Steckler, T., Plath, N., Lerdrup, L., Ruby, T., Haman, M., Wyler, R., et al. (2015) · Psychopharmacology

Schizophrenia research and treatmentNeurotransmitter Receptor Influence on Behavior

Cited by 43

Animal Paradigms to Assess Cognition with Translation to Humans

Wallace, T. L., Ballard, T. M., & Glavis-Bloom, C. (2015) · Handbook of Experimental Pharmacology

Animal testing and alternativesMemory and Neural Mechanisms

Cited by 26