Lai, Chooi-May

Functional and structural recovery of the retina after gene therapy in the RPE65 null mutation dog

Narfstro¨m, K., Katz, M. L., Bragadottir, R., Seeliger, M., Boulanger, A., Redmond, T. M., Caro, L., Lai, C.-M., & Rakoczy, P. E. (2003) · Investigative Opthalmology & Visual Science

Retinal Development and DisordersVirus-based gene therapy research

Cited by 252

Gene therapy with recombinant adeno-associated vectors for neovascular age-related macular degeneration: 1 year follow-up of a phase 1 randomised clinical trial

Rakoczy, E. P., Lai, C.-M., Magno, A. L., Wikstrom, M. E., French, M. A., Pierce, C. M., Schwartz, S. D., Blumenkranz, M. S., Chalberg, T. W., Degli-Esposti, M. A., et al. (2015) · The Lancet

Retinal Diseases and TreatmentsRetinal Development and Disorders

Cited by 189

Progressive age-related changes similar to age-related macular degeneration in a transgenic mouse model

Rakoczy, P. E., Zhang, D., Robertson, T., Barnett, N. L., Papadimitriou, J., Constable, I. J., & Lai, C.-M. (2002) · The American Journal of Pathology

Retinal Diseases and TreatmentsRetinal Development and Disorders

Cited by 173

Phase 2a randomized clinical trial: safety and post hoc analysis of subretinal rAAV.sFLT-1 for wet age-related macular degeneration

Constable, I. J., Pierce, C. M., Lai, C.-M., Magno, A. L., Degli-Esposti, M. A., French, M. A., McAllister, I. L., Butler, S., Barone, S. B., Schwartz, S. D., et al. (2016) · EBioMedicine

Retinal Diseases and TreatmentsRetinal Development and Disorders

Cited by 152

Characterization of a Mouse Model of Hyperglycemia and Retinal Neovascularization

Rakoczy, E. P., Rahman, I. S. A., Binz, N., Li, C.-R., Vagaja, N. N., de Pinho, M., & Lai, C.-M. (2010) · The American Journal of Pathology

Retinal Diseases and TreatmentsRetinal Imaging and Analysis

Cited by 114

Gene Therapy in Neovascular Age-related Macular Degeneration: Three-Year Follow-up of a Phase 1 Randomized Dose Escalation Trial

Constable, I. J., Lai, C.-M., Magno, A. L., French, M. A., Barone, S. B., Schwartz, S. D., Blumenkranz, M. S., Degli-Esposti, M. A., & Rakoczy, E. P. (2017) · American Journal of Ophthalmology

Retinal Diseases and TreatmentsRetinal Development and Disorders

Cited by 76

Three-year follow-up of phase 1 and 2a rAAV.sFLT-1 subretinal gene therapy trials for exudative age-related macular degeneration

Rakoczy, E. P., Magno, A. L., Lai, C.-M., Pierce, C. M., Degli-Esposti, M. A., Blumenkranz, M. S., & Constable, I. J. (2019) · American Journal of Ophthalmology

Retinal Diseases and TreatmentsRetinal Development and Disorders

Cited by 70

Controlled production of active Cathepsin D in Retinal Pigment Epithelial cells following adenovirus-mediated gene delivery

Lai, C.-M., Robertson, T., Papadimitriou, J., Shen, W.-Y., Daw, N., Constable, I. J., & Rakoczy, P. E. (2000) · Molecular Therapy

Protease and Inhibitor MechanismsRetinal Development and Disorders

Cited by 5