Plate, Karl H.

Deletion of the hypoxia-response element in the vascular endothelial growth factor promoter causes motor neuron degeneration

Oosthuyse, B., Moons, L., Storkebaum, E., Beck, H., Nuyens, D., Brusselmans, K., Dorpe, J. V., Hellings, P., Gorselink, M., Heymans, S., et al. (2001) · Nature Genetics

Amyotrophic Lateral Sclerosis ResearchAngiogenesis and VEGF in Cancer

Cited by 1,007

Functional morphology of the blood–brain barrier in health and disease

Liebner, S., Dijkhuizen, R. M., Reiss, Y., Plate, K. H., Agalliu, D., & Constantin, G. (2018) · Acta Neuropathologica

Barrier Structure and Function StudiesDrug Transport and Resistance Mechanisms

Cited by 872

Wnt/β-catenin signaling controls development of the blood–brain barrier

Liebner, S., Corada, M., Bangsow, T., Babbage, J., Taddei, A., Czupalla, C. J., Reis, M., Felici, A., Wolburg, H., Fruttiger, M., et al. (2008) · The Journal of Cell Biology

Barrier Structure and Function StudiesDrug Transport and Resistance Mechanisms

Cited by 860

Extracellular Vesicle-Mediated Transfer of Genetic Information between the Hematopoietic System and the Brain in Response to Inflammation

Ridder, K., Keller, S., Dams, M., Rupp, A.-K., Schlaudraff, J., Del Turco, D., Starmann, J., Macas, J., Karpova, D., Devraj, K., et al. (2014) · PLoS Biology

Extracellular vesicles in diseaseNeuroinflammation and Neurodegeneration Mechanisms

Cited by 412

Up-regulation of hypoxia-inducible factors HIF-1α and HIF-2α under normoxic conditions in renal carcinoma cells by von Hippel-Lindau tumor suppressor gene loss of function

Krieg, M., Haas, R., Brauch, H., Acker, T., Flamme, I., & Plate, K. H. (2000) · Oncogene

Cancer, Hypoxia, and MetabolismRenal cell carcinoma treatment

Cited by 396

Uncontrolled expression of vascular endothelial growth factor and its receptors leads to insufficient skin angiogenesis in patients with systemic sclerosis

Distler, O., Distler, J. H. W., Scheid, A., Acker, T., Hirth, A., Rethage, J., Michel, B. A., Gay, R. E., Müller-Ladner, U., Matucci-Cerinic, M., et al. (2004) · Circulation Research

Systemic Sclerosis and Related DiseasesAngiogenesis and VEGF in Cancer

Cited by 310

Angiopoietin‐2: a multifaceted cytokine that functions in both angiogenesis and inflammation

Scholz, A., Plate, K. H., & Reiss, Y. (2015) · Annals of the New York Academy of Sciences

Angiogenesis and VEGF in CancerCytokine Signaling Pathways and Interactions

Cited by 248

Angiopoietin 2 Stimulates TIE2-Expressing Monocytes To Suppress T Cell Activation and To Promote Regulatory T Cell Expansion

Coffelt, S. B., Chen, Y.-Y., Muthana, M., Welford, A. F., Tal, A. O., Scholz, A., Plate, K. H., Reiss, Y., Murdoch, C., De Palma, M., et al. (2011) · The Journal of Immunology

Immune cells in cancerAngiogenesis and VEGF in Cancer

Cited by 220

Endothelial Wnt/β-catenin signaling inhibits glioma angiogenesis and normalizes tumor blood vessels by inducing PDGF-B expression

Reis, M., Czupalla, C. J., Ziegler, N., Devraj, K., Zinke, J., Seidel, S., Heck, R., Thom, S., Macas, J., Bockamp, E., et al. (2012) · Journal of Experimental Medicine

Angiogenesis and VEGF in CancerBarrier Structure and Function Studies

Cited by 167

Different networks, common growth factors: shared growth factors and receptors of the vascular and the nervous system

Raab, S., & Plate, K. H. (2007) · Acta Neuropathologica

Nerve injury and regenerationAngiogenesis and VEGF in Cancer

Cited by 120

Angiopoietin-2 promotes myeloid cell infiltration in a β2-integrin–dependent manner

Scholz, A., Lang, V., Henschler, R., Czabanka, M., Vajkoczy, P., Chavakis, E., Drynski, J., Harter, P. N., Mittelbronn, M., Dumont, D. J., et al. (2011) · Blood

Cell Adhesion Molecules ResearchAngiogenesis and VEGF in Cancer

Cited by 102

Brain homeostasis: VEGF receptor 1 and 2—two unequal brothers in mind

Wittko-Schneider, I. M., Schneider, F. T., & Plate, K. H. (2013) · Cellular and Molecular Life Sciences

Angiogenesis and VEGF in CancerBarrier Structure and Function Studies

Cited by 62

Loss of FUBP1 expression in gliomas predicts FUBP1 mutation and is associated with oligodendroglial differentiation, IDH1 mutation and 1p/19q loss of heterozygosity

Baumgarten, P., Harter, P. N., Tönjes, M., Capper, D., Blank, A. ‐., Sahm, F., von Deimling, A., Kolluru, V., Schwamb, B., Rabenhorst, U., et al. (2014) · Neuropathology and Applied Neurobiology

Glioma Diagnosis and TreatmentAcute Myeloid Leukemia Research

Cited by 53

Junctional Adhesion Molecule (JAM)-C Deficient C57BL/6 Mice Develop a Severe Hydrocephalus

Wyss, L., Schäfer, J., Liebner, S., Mittelbronn, M., Deutsch, U., Enzmann, G., Adams, R. H., Aurrand-Lions, M., Plate, K. H., Imhof, B. A., et al. (2012) · PLoS ONE

Cerebrospinal fluid and hydrocephalusBarrier Structure and Function Studies

Cited by 42

Netrin-1 Expression Is an Independent Prognostic Factor for Poor Patient Survival in Brain Metastases

Harter, P. N., Zinke, J., Scholz, A., Tichy, J., Zachskorn, C., Kvasnicka, H. M., Goeppert, B., Delloye-Bourgeois, C., Hattingen, E., Senft, C., et al. (2014) · PLoS ONE

Brain Metastases and TreatmentGlioma Diagnosis and Treatment

Cited by 41