Yao, David

CRISPR screens in cancer spheroids identify 3D growth-specific vulnerabilities

Han, K., Pierce, S. E., Li, A., Spees, K., Anderson, G. R., Seoane, J. A., Lo, Y.-H., Dubreuil, M., Olivas, M., Kamber, R. A., et al. (2020) · Nature

CRISPR and Genetic EngineeringCancer Genomics and Diagnostics

Cited by 311

Methods and Applications of CRISPR-Mediated Base Editing in Eukaryotic Genomes

Hess, G. T., Tycko, J., Yao, D., & Bassik, M. C. (2017) · Molecular Cell

CRISPR and Genetic EngineeringRNA regulation and disease

Cited by 234

A Multiplexed Assay for Exon Recognition Reveals that an Unappreciated Fraction of Rare Genetic Variants Cause Large-Effect Splicing Disruptions

Chong, R., Insigne, K. D., Yao, D., Burghard, C. P., Wang, J., Hsiao, Y.-H. E., Jones, E. M., Goodman, D. B., Xiao, X., & Kosuri, S. (2019) · Molecular Cell

RNA Research and SplicingGenomics and Rare Diseases

Cited by 130

An encyclopedia of enhancer-gene regulatory interactions in the human genome

Gschwind, A. R., Mualim, K. S., Karbalayghareh, A., Sheth, M. U., Dey, K. K., Jagoda, E., Nurtdinov, R. N., Xi, W., Tan, A. S., Jones, H., et al. (2023) · bioRxiv (Cold Spring Harbor Laboratory)

Genomics and Chromatin DynamicsGenetic Associations and Epidemiology

Cited by 119

Development of compact transcriptional effectors using high-throughput measurements in diverse contexts

Tycko, J., Van, M. V., Aradhana, DelRosso, N., Ye, H., Yao, D., Valbuena, R., Vaughan-Jackson, A., Xu, X., Ludwig, C., et al. (2025) · Nature Biotechnology

CRISPR and Genetic EngineeringGenomics and Chromatin Dynamics

Cited by 57

Long-range regulation of transcription scales with genomic distance in a gene-specific manner

Jensen, C. L., Chen, L.-F., Swigut, T., Crocker, O. J., Yao, D., Bassik, M. C., Ferrell, J. E., Boettiger, A. N., & Wysocka, J. (2025) · Molecular Cell

Genomics and Chromatin DynamicsCRISPR and Genetic Engineering

Cited by 39