Sausville, E

Jasplakinolide, a cytotoxic natural product, induces actin polymerization and competitively inhibits the binding of phalloidin to F-actin.

Bubb, M. R., Senderowicz, A. M., Sausville, E. A., Duncan, K. L., & Korn, E. D. (1994) · Journal of Biological Chemistry

Cellular Mechanics and InteractionsMarine Sponges and Natural Products

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UCN-01: a potent abrogator of G2 checkpoint function in cancer cells with disrupted p53

Wang, Q., Fan, S., Eastman, A., Worland, P. J., Sausville, E. A., & O'Connor, P. M. (1996) · JNCI Journal of the National Cancer Institute

Cancer-related Molecular PathwaysDNA Repair Mechanisms

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The human vasopressin gene is linked to the oxytocin gene and is selectively expressed in a cultured lung cancer cell line.

Sausville, E., Carney, D., & Battey, J. (1985) · Journal of Biological Chemistry

Neuroendocrine regulation and behaviorNeuropeptides and Animal Physiology

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Flavopiridol (L86 8275; NSC 649890), a new kinase inhibitor for tumor therapy

Sedlacek, H., Czech, J., Naik, R., Kaur, G., Worland, P., Losiewicz, M., Parker, B., Carlson, B., Smith, A., Senderowicz, A., et al. (1996) · International Journal of Oncology

Flavonoids in Medical ResearchHeterocyclic Compound Synthesis and Bioactivity

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Mammalian target of rapamycin, a molecular target in squamous cell carcinomas of the head and neck

Amornphimoltham, P., Patel, V., Sodhi, A., Nikitakis, N. G., Sauk, J. J., Sausville, E. A., Molinolo, A. A., & Gutkind, J. S. (2005) · Cancer Research

PI3K/AKT/mTOR signaling in cancerHead and Neck Cancer Studies

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Cucurbitacin E-induced disruption of the actin and vimentin cytoskeleton in prostate carcinoma cells

Duncan, K. L. K., Duncan, M. D., Alley, M. C., & Sausville, E. A. (1996) · Biochemical Pharmacology

Cellular Mechanics and InteractionsMicrotubule and mitosis dynamics

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