Kazazian, Haig H.

Mobile Elements: Drivers of Genome Evolution

Kazazian, H. H. (2004) · Science

Chromosomal and Genetic VariationsGenome Rearrangement Algorithms

Cited by 1,922

Human L1 retrotransposon encodes a conserved endonuclease required for retrotransposition

Feng, Q., Moran, J. V., Kazazian, H. H., & Boeke, J. D. (1996) · Cell

Chromosomal and Genetic VariationsGenomic variations and chromosomal abnormalities

Cited by 1,139

Hot L1s account for the bulk of retrotransposition in the human population

Brouha, B., Schustak, J., Badge, R. M., Lutz-Prigge, S., Farley, A. H., Moran, J. V., & Kazazian, H. H. (2003) · Proceedings of the National Academy of Sciences

Chromosomal and Genetic VariationsGenomic variations and chromosomal abnormalities

Cited by 1,073

High frequency retrotransposition in cultured mammalian cells

Moran, J. V., Holmes, S. E., Naas, T. P., DeBerardinis, R. J., Boeke, J. D., & Kazazian, H. H. (1996) · Cell

Chromosomal and Genetic VariationsGenomic variations and chromosomal abnormalities

Cited by 1,022

Roles for retrotransposon insertions in human disease

Hancks, D. C., & Kazazian, H. H. (2016) · Mobile DNA

Chromosomal and Genetic VariationsGenomic variations and chromosomal abnormalities

Cited by 670

Active human retrotransposons: variation and disease

Hancks, D. C., & Kazazian, H. H. (2012) · Current Opinion in Genetics & Development

Chromosomal and Genetic VariationsGenomic variations and chromosomal abnormalities

Cited by 592

Mobile elements and mammalian genome evolution

Deininger, P. L., Moran, J. V., Batzer, M. A., & Kazazian, H. H. (2003) · Current Opinion in Genetics & Development

Chromosomal and Genetic VariationsGenomic variations and chromosomal abnormalities

Cited by 479

Pan-cancer analysis of whole genomes identifies driver rearrangements promoted by LINE-1 retrotransposition

Rodriguez-Martin, B., Alvarez, E. G., Baez-Ortega, A., Zamora, J., Supek, F., Demeulemeester, J., Santamarina, M., Ju, Y. S., Temes, J., Garcia-Souto, D., et al. (2020) · Nature Genetics

Genomic variations and chromosomal abnormalitiesCancer Genomics and Diagnostics

Cited by 451

Mobile DNA in Health and Disease

Kazazian, H. H., & Moran, J. V. (2017) · New England Journal of Medicine

Chromosomal and Genetic VariationsGenomic variations and chromosomal abnormalities

Cited by 445

Abnormal RNA processing due to the exon mutation of βE-globin gene

Orkin, S. H., Kazazian, H. H., Antonarakis, S. E., Ostrer, H., Goff, S. C., & Sexton, J. P. (1982) · Nature

Hemoglobinopathies and Related DisordersRNA Research and Splicing

Cited by 298

L1 retrotransposition can occur early in human embryonic development

van den Hurk, J. A. J. M., Meij, I. C., del Carmen Seleme, M., Kano, H., Nikopoulos, K., Hoefsloot, L. H., Sistermans, E. A., de Wijs, I. J., Mukhopadhyay, A., Plomp, A. S., et al. (2007) · Human Molecular Genetics

Chromosomal and Genetic VariationsGenomic variations and chromosomal abnormalities

Cited by 193

Eradication of neutralizing antibodies to factor VIII in canine hemophilia a after liver gene therapy

Finn, J. D., Ozelo, M. C., Sabatino, D. E., Franck, H. W. G., Merricks, E. P., Crudele, J. M., Zhou, S., Kazazian, H. H., Lillicrap, D., Nichols, T. C., et al. (2010) · Blood

Hemophilia Treatment and ResearchVirus-based gene therapy research

Cited by 157

Evidence consistent with human L1 retrotransposition in maternal meiosis I

Brouha, B., Meischl, C., Ostertag, E., de Boer, M., Zhang, Y., Neijens, H., Roos, D., & Kazazian, H. H. (2002) · The American Journal of Human Genetics

Chromosomal and Genetic VariationsGenomic variations and chromosomal abnormalities

Cited by 122

Many LINE1 elements contribute to the transcriptome of human somatic cells

Rangwala, S. H., Zhang, L., & Kazazian, H. H. (2009) · Genome Biology

Chromosomal and Genetic VariationsGenomic variations and chromosomal abnormalities

Cited by 102