Mancuso, Anthony

Beyond aerobic glycolysis: transformed cells can engage in glutamine metabolism that exceeds the requirement for protein and nucleotide synthesis

DeBerardinis, R. J., Mancuso, A., Daikhin, E., Nissim, I., Yudkoff, M., Wehrli, S., & Thompson, C. B. (2007) · Proceedings of the National Academy of Sciences

Cancer, Hypoxia, and MetabolismAmino Acid Enzymes and Metabolism

Cited by 2,622

Myc regulates a transcriptional program that stimulates mitochondrial glutaminolysis and leads to glutamine addiction

Wise, D. R., DeBerardinis, R. J., Mancuso, A., Sayed, N., Zhang, X.-Y., Pfeiffer, H. K., Nissim, I., Daikhin, E., Yudkoff, M., McMahon, S. B., et al. (2008) · Proceedings of the National Academy of Sciences

Cancer, Hypoxia, and MetabolismAmino Acid Enzymes and Metabolism

Cited by 2,001

Fructose-1,6-bisphosphatase opposes renal carcinoma progression

Li, B., Qiu, B., Lee, D. S. M., Walton, Z. E., Ochocki, J. D., Mathew, L. K., Mancuso, A., Gade, T. P. F., Keith, B., Nissim, I., et al. (2014) · Nature

Cancer, Hypoxia, and MetabolismRenal cell carcinoma treatment

Cited by 535

Reciprocal regulation of p53 and malic enzymes modulates metabolism and senescence

Jiang, P., Du, W., Mancuso, A., Wellen, K. E., & Yang, X. (2013) · Nature

Telomeres, Telomerase, and SenescenceCancer-related Molecular Pathways

Cited by 491

Targeted inhibition of tumor-specific glutaminase diminishes cell-autonomous tumorigenesis

Xiang, Y., Stine, Z. E., Xia, J., Lu, Y., O’Connor, R. S., Altman, B. J., Hsieh, A. L., Gouw, A. M., Thomas, A. G., Gao, P., et al. (2015) · Journal of Clinical Investigation

Cancer, Hypoxia, and MetabolismAmino Acid Enzymes and Metabolism

Cited by 409

The hexosamine biosynthetic pathway couples growth factor-induced glutamine uptake to glucose metabolism

Wellen, K. E., Lu, C., Mancuso, A., Lemons, J. M. S., Ryczko, M., Dennis, J. W., Rabinowitz, J. D., Coller, H. A., & Thompson, C. B. (2010) · Genes & Development

Cancer, Hypoxia, and MetabolismGlycosylation and Glycoproteins Research

Cited by 377

Imatinib resistance associated with BCR-ABL upregulation is dependent on HIF-1α-induced metabolic reprograming

Zhao, F., Mancuso, A., Bui, T. V., Tong, X., Gruber, J. J., Swider, C. R., Sanchez, P. V., Lum, J. J., Sayed, N., Melo, J. V., et al. (2010) · Oncogene

Chronic Myeloid Leukemia TreatmentsCancer, Hypoxia, and Metabolism

Cited by 179

Gadolinium-DTPA-enhanced magnetic resonance imaging in optic neuropathies

Guy, J., Mancuso, A., Quisling, R. G., Beck, R., & Moster, M. (1990) · Ophthalmology

Multiple Sclerosis Research StudiesGlaucoma and retinal disorders

Cited by 90

Applications of Artificial Intelligence in the Radiology Roundtrip: Process Streamlining, Workflow Optimization, and Beyond

Pierre, K., Haneberg, A. G., Kwak, S., Peters, K. R., Hochhegger, B., Sananmuang, T., Tunlayadechanont, P., Tighe, P. J., Mancuso, A., & Forghani, R. (2023) · Seminars in Roentgenology

Artificial Intelligence in Healthcare and EducationRadiology practices and education

Cited by 79