Du, Yuhong

An expanded universe of cancer targets

Hahn, W. C., Bader, J. S., Braun, T. P., Califano, A., Clemons, P. A., Druker, B. J., Ewald, A. J., Fu, H., Jagu, S., Kemp, C. J., et al. (2021) · Cell

Cancer Genomics and DiagnosticsChromatin Remodeling and Cancer

Cited by 213

A CRISPR/Cas9-Engineered ARID1A -Deficient Human Gastric Cancer Organoid Model Reveals Essential and Nonessential Modes of Oncogenic Transformation

Lo, Y.-H., Kolahi, K. S., Du, Y., Chang, C.-Y., Krokhotin, A., Nair, A., Sobba, W. D., Karlsson, K., Jones, S. J., Longacre, T. A., et al. (2021) · Cancer Discovery

Chromatin Remodeling and CancerCRISPR and Genetic Engineering

Cited by 174

Inhibition of delta-secretase improves cognitive functions in mouse models of Alzheimer’s disease

Zhang, Z., Obianyo, O., Dall, E., Du, Y., Fu, H., Liu, X., Kang, S. S., Song, M., Yu, S.-P., Cabrele, C., et al. (2017) · Nature Communications

Alzheimer's disease research and treatmentsCholinesterase and Neurodegenerative Diseases

Cited by 146

Development of a miniaturized 3D organoid culture platform for ultra-high-throughput screening

Du, Y., Li, X., Niu, Q., Mo, X., Qui, M., Ma, T., Kuo, C. J., & Fu, H. (2020) · Journal of Molecular Cell Biology

3D Printing in Biomedical ResearchCancer Cells and Metastasis

Cited by 125

Discovery and structural characterization of a small molecule 14-3-3 protein-protein interaction inhibitor

Zhao, J., Du, Y., Horton, J. R., Upadhyay, A. K., Lou, B., Bai, Y., Zhang, X., Du, L., Li, M., Wang, B., et al. (2011) · Proceedings of the National Academy of Sciences

14-3-3 protein interactionsProtein Kinase Regulation and GTPase Signaling

Cited by 105

Discovery of Dual Inhibitors of MDM2 and XIAP for Cancer Treatment

Gu, L., Zhang, H., Liu, T., Zhou, S., Du, Y., Xiong, J., Yi, S., Qu, C.-K., Fu, H., & Zhou, M. (2016) · Cancer Cell

Cancer-related Molecular PathwaysPI3K/AKT/mTOR signaling in cancer

Cited by 86