Faust, Phyllis L.

A tuberous sclerosis complex signalling node at the peroxisome regulates mTORC1 and autophagy in response to ROS

Zhang, J., Kim, J., Alexander, A., Cai, S., Tripathi, D. N., Dere, R., Tee, A. R., Tait-Mulder, J., Di Nardo, A., Han, J. M., et al. (2013) · Nature Cell Biology

Tuberous Sclerosis Complex ResearchPI3K/AKT/mTOR signaling in cancer

Cited by 258

Targeted deletion of the PEX2 peroxisome assembly gene in mice provides a model for Zellweger syndrome, a human neuronal migration disorder

Faust, P. L., & Hatten, M. E. (1997) · The Journal of Cell Biology

Metabolism and Genetic DisordersLysosomal Storage Disorders Research

Cited by 157

Cholesterol biosynthesis and ER stress in peroxisome deficiency

Faust, P. L., & Kovacs, W. J. (2014) · Biochimie

Cholesterol and Lipid MetabolismCancer, Lipids, and Metabolism

Cited by 107

Peroxisome biogenesis disorders: the role of peroxisomes and metabolic dysfunction in developing brain

Faust, P. L., Banka, D., Siriratsivawong, R., Ng, V. G., & Wikander, T. M. (2005) · Journal of Inherited Metabolic Disease

Metabolism and Genetic DisordersLysosomal Storage Disorders Research

Cited by 82

Abnormal cerebellar histogenesis in PEX2 Zellweger mice reflects multiple neuronal defects induced by peroxisome deficiency

Faust, P. L. (2003) · Journal of Comparative Neurology

Neurogenesis and neuroplasticity mechanismsMetabolism and Genetic Disorders

Cited by 71

Bile acid treatment alters hepatic disease and bile acid transport in peroxisome-deficient PEX2 Zellweger mice

Keane, M. H., Overmars, H., Wikander, T. M., Ferdinandusse, S., Duran, M., Wanders, R. J. A., & Faust, P. L. (2007) · Hepatology

Metabolism and Genetic DisordersDrug Transport and Resistance Mechanisms

Cited by 68

The peroxisome deficient PEX2 Zellweger mouse: pathologic and biochemical correlates of lipid dysfunction

Faust, P. L., Su, H.-M., Moser, A., & Moser, H. W. (2001) · Journal of Molecular Neuroscience

Metabolism and Genetic DisordersNeurological diseases and metabolism

Cited by 60

The Pex1-G844D mouse: a model for mild human Zellweger spectrum disorder

Hiebler, S., Masuda, T., Hacia, J. G., Moser, A. B., Faust, P. L., Liu, A., Chowdhury, N., Huang, N., Lauer, A., Bennett, J., et al. (2014) · Molecular Genetics and Metabolism

Metabolism and Genetic DisordersLysosomal Storage Disorders Research

Cited by 60

Functional Peroxisomes Are Essential for Efficient Cholesterol Sensing and Synthesis

Charles, K. N., Shackelford, J. E., Faust, P. L., Fliesler, S. J., Stangl, H., & Kovacs, W. J. (2020) · Frontiers in Cell and Developmental Biology

Cholesterol and Lipid MetabolismCancer, Lipids, and Metabolism

Cited by 36