Waterman, Michael R.

Regulation of the synthesis of steroidogenic enzymes in adrenal cortical cells by ACTH

Simpson, E. R., & Waterman, M. R. (1988) · Annual Review of Physiology

Adrenal Hormones and DisordersStress Responses and Cortisol

Cited by 506

17α-Hydroxylase/17,20 lyase deficiency: from clinical investigation to molecular definition

YANASE, T., SIMPSON, E. R., & WATERMAN, M. R. (1991) · Endocrine Reviews

Sexual Differentiation and DisordersAdrenal Hormones and Disorders

Cited by 390

Expression of Bovine 17α-Hydroxylase Cytochrome P-450 cDNA in Nonsteroidogenic (COS 1) Cells

Zuber, M. X., Simpson, E. R., & Waterman, M. R. (1986) · Science

Steroid Chemistry and BiochemistryAdrenal Hormones and Disorders

Cited by 388

The role of cytochrome b5 in the biosynthesis of androgens by human P450c17

Katagiri, M., Kagawa, N., & Waterman, M. R. (1995) · Archives of Biochemistry and Biophysics

Steroid Chemistry and BiochemistryAdrenal Hormones and Disorders

Cited by 223

Transcriptional regulation of steroid hydroxylase genes by corticotropin

John, M. E., John, M. C., Boggaram, V, Simpson, E. R., & Waterman, M. R. (1986) · Proceedings of the National Academy of Sciences

Adrenal Hormones and DisordersEstrogen and related hormone effects

Cited by 217

Identification by site-directed mutagenesis of two lysine residues in cholesterol side chain cleavage cytochrome P450 that are essential for adrenodoxin binding

Wada, A., & Waterman, M. R. (1992) · Journal of Biological Chemistry

Metal-Catalyzed Oxygenation MechanismsMetalloenzymes and iron-sulfur proteins

Cited by 141

Transcriptional Activation of Human CYP17 in H295R Adrenocortical Cells Depends on Complex Formation among p54nrb/NonO, Protein-Associated Splicing Factor, and SF-1, a Complex That Also Participates in Repression of Transcription

Sewer, M. B., Nguyen, V. Q., Huang, C.-J., Tucker, P. W., Kagawa, N., & Waterman, M. R. (2002) · Endocrinology

Estrogen and related hormone effectsGenomics and Chromatin Dynamics

Cited by 123

Identification and characterization of cDNA clones specific for cholesterol side-chain cleavage cytochrome P-450

John, M. E., John, M. C., Ashley, P., MacDonald, R. J., Simpson, E. R., & Waterman, M. R. (1984) · Proceedings of the National Academy of Sciences

Adrenal Hormones and DisordersEstrogen and related hormone effects

Cited by 119

Localization of the human CYP17 gene (cytochrome P45017α) to 10q24.3 by fluorescence in situ hybridization and simultaneous chromosome banding

Fan, Y.-S., Sasi, R., Lee, C., Winter, J. S. D., Waterman, M. R., & Lin, C. C. (1992) · Genomics

Sexual Differentiation and DisordersGenomic variations and chromosomal abnormalities

Cited by 102

Induction of synthesis of mitochondrial steroidogenic enzymes of bovine adrenocortical cells by analogs of cyclic AMP

Kramer, R. E., Rainey, W. E., Funkenstein, B., Dee, A., Simpson, E. R., & Waterman, M. R. (1984) · Journal of Biological Chemistry

Adrenal Hormones and DisordersEstrogen and related hormone effects

Cited by 91

P450(17 alpha) and P450SCC gene expression and regulation in the rat placenta.

Durkee, T. J., McLean, M. P., Hales, D. B., Payne, A. H., Waterman, M. R., Khan, I., & Gibori, G. (1992) · Endocrinology

Pregnancy and preeclampsia studiesEstrogen and related hormone effects

Cited by 61

Bovine steroid 21-hydroxylase: regulation of biosynthesis

John, M. E., Okamura, T., Dee, A., Adler, B., John, M. C., White, P. C., Simpson, E. R., & Waterman, M. R. (1986) · Biochemistry

Adrenal Hormones and DisordersHormonal Regulation and Hypertension

Cited by 61

A second FMN binding site in yeast NADPH-cytochrome P450 reductase suggests a mechanism of electron transfer by diflavin reductases

Lamb, D. C., Kim, Y., Yermalitskaya, L. V., Yermalitsky, V. N., Lepesheva, G. I., Kelly, S. L., Waterman, M. R., & Podust, L. M. (2006) · Structure

Enzyme Structure and FunctionMetal-Catalyzed Oxygenation Mechanisms

Cited by 60

Molecular basis of apparent isolated 17,20-lyase deficiency: compound heterozygous mutations in the C-terminal region (Arg(496) → Cys, Gln(461) → Stop) actually cause combined 17α-hydroxylase/17,20-lyase deficiency

Yanase, T., Waterman, M. R., Zachmann, M., Winter, J. S. D., Simpson, E. R., & Kagimoto, M. (1992) · Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease

Sexual Differentiation and DisordersAdrenal Hormones and Disorders

Cited by 50

Functional analysis of human cytochrome P450 21A2 variants involved in congenital adrenal hyperplasia

Wang, C., Pallan, P. S., Zhang, W., Lei, L., Yoshimoto, F. K., Waterman, M. R., Egli, M., & Guengerich, F. P. (2017) · Journal of Biological Chemistry

Sexual Differentiation and DisordersAdrenal Hormones and Disorders

Cited by 43

Structural Analysis of Cytochrome P450 105N1 Involved in the Biosynthesis of the Zincophore, Coelibactin

Zhao, B., Moody, S. C., Hider, R. C., Lei, L., Kelly, S. L., Waterman, M. R., & Lamb, D. C. (2012) · International Journal of Molecular Sciences

Microbial Natural Products and BiosynthesisMetal-Catalyzed Oxygenation Mechanisms

Cited by 42

Research resource: correlating human cytochrome P450 21A2 crystal structure and phenotypes of mutations in congenital adrenal hyperplasia

Pallan, P. S., Lei, L., Wang, C., Waterman, M. R., Guengerich, F. P., & Egli, M. (2015) · Molecular Endocrinology

Sexual Differentiation and DisordersAdrenal Hormones and Disorders

Cited by 19