Wise, Kim S.

Design and synthesis of a minimal bacterial genome

Hutchison, C. A., Chuang, R.-Y., Noskov, V. N., Assad-Garcia, N., Deerinck, T. J., Ellisman, M. H., Gill, J., Kannan, K., Karas, B. J., Ma, L., et al. (2016) · Science

Microbial Metabolic Engineering and BioproductionRNA and protein synthesis mechanisms

Cited by 1,500

Essential metabolism for a minimal cell

Breuer, M., Earnest, E. E., Merryman, C., Wise, K. S., Sun, L., Lynott, M. R., Hutchison, C. A., Smith, H. O., Lapek, J. D., Gonzalez, D. J., et al. (2019) · eLife

Microbial Metabolic Engineering and BioproductionGene Regulatory Network Analysis

Cited by 190

Fundamental behaviors emerge from simulations of a living minimal cell

Thornburg, Z. R., Bianchi, D. M., Brier, T. A., Gilbert, B. R., Earnest, E. E., Melo, M. C. R., Safronova, N., Sáenz, J. P., Cook, A. T., Wise, K. S., et al. (2022) · Cell

Lipid Membrane Structure and BehaviorLipid metabolism and biosynthesis

Cited by 165

Genetic requirements for cell division in a genomically minimal cell

Pelletier, J. F., Sun, L., Wise, K. S., Assad-Garcia, N., Karas, B. J., Deerinck, T. J., Ellisman, M. H., Mershin, A., Gershenfeld, N., Chuang, R.-Y., et al. (2020) · bioRxiv / Cell

Bacterial Genetics and BiotechnologyMicrobial Metabolic Engineering and Bioproduction

Cited by 148

Evolution of a minimal cell

Moger-Reischer, R. Z., Glass, J. I., Wise, K. S., Sun, L., Bittencourt, D. M. C., Lehmkuhl, B. K., Schoolmaster, D. R., Lynch, M., & Lennon, J. T. (2023) · Nature

Evolution and Genetic DynamicsMicrobial Metabolic Engineering and Bioproduction

Cited by 116

Metabolite Damage and Damage-Control in a Minimal Genome

Haas, D., Thamm, A. M., Sun, J., Huang, L., Sun, L., Beaudoin, G. A. W., Wise, K. S., Lerma-Ortiz, C., Bruner, S. D., Breuer, M., et al. (2021) · mBio

Microbial Metabolic Engineering and BioproductionBacterial Genetics and Biotechnology

Cited by 24

Adaptive evolution of a minimal organism with a synthetic genome

Sandberg, T. E., Wise, K. S., Dalldorf, C., Szubin, R., Feist, A. M., Glass, J. I., & Palsson, B. O. (2023) · iScience

Evolution and Genetic DynamicsMicrobial Metabolic Engineering and Bioproduction

Cited by 23