Chang, Lufen

A central role for JNK in obesity and insulin resistance

Hirosumi, J., Tuncman, G., Chang, L., Görgün, C. Z., Uysal, K. T., Maeda, K., Karin, M., & Hotamisligil, G. S. (2002) · Nature

Adipokines, Inflammation, and Metabolic DiseasesMetabolism, Diabetes, and Cancer

Cited by 3,359

Reactive Oxygen Species Promote TNFα-Induced Death and Sustained JNK Activation by Inhibiting MAP Kinase Phosphatases

Kamata, H., Honda, S.-I., Maeda, S., Chang, L., Hirata, H., & Karin, M. (2005) · Cell

Redox biology and oxidative stressCell death mechanisms and regulation

Cited by 1,792

The E3 Ubiquitin Ligase Itch Couples JNK Activation to TNFα-induced Cell Death by Inducing c-FLIPL Turnover

Chang, L., Kamata, H., Solinas, G., Luo, J.-L., Maeda, S., Venuprasad, K., Liu, Y.-C., & Karin, M. (2006) · Cell

NF-κB Signaling PathwaysUbiquitin and proteasome pathways

Cited by 706

Functional in vivo interactions between JNK1 and JNK2 isoforms in obesity and insulin resistance

Tuncman, G., Hirosumi, J., Solinas, G., Chang, L., Karin, M., & Hotamisligil, G. S. (2006) · Proceedings of the National Academy of Sciences

Adipokines, Inflammation, and Metabolic DiseasesMetabolism, Diabetes, and Cancer

Cited by 350

IKKβ Is Required for Prevention of Apoptosis Mediated by Cell-Bound but Not by Circulating TNFα

Maeda, S., Chang, L., Li, Z.-W., Luo, J.-L., Leffert, H., & Karin, M. (2003) · Immunity

NF-κB Signaling PathwaysCell death mechanisms and regulation

Cited by 286