Brunk, Ulf T.

Guidelines for the use and interpretation of assays for monitoring autophagy

Klionsky, D. J., Abdalla, F. C., Abeliovich, H., Abraham, R. T., Acevedo-Arozena, A., Adeli, K., Agholme, L., Agnello, M., Agostinis, P., Aguirre-Ghiso, J. A., et al. (2012) · Autophagy

Autophagy in Disease and TherapyCalcium signaling and nucleotide metabolism

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Lipofuscin: mechanisms of age-related accumulation and influence on cell function12 1Guest Editor: Rajindar S. Sohal 2This article is part of a series of reviews on “Oxidative Stress and Aging.” The full list of papers may be found on the homepage of the journal.

Brunk, U. T., & Terman, A. (2002) · Free Radical Biology and Medicine

Autophagy in Disease and TherapyGenetics, Aging, and Longevity in Model Organisms

Cited by 919

Autophagy and aging: The importance of maintaining "clean" cells

Cuervo, A. M., Bergamini, E., Brunk, U. T., Dröge, W., Ffrench, M., & Terman, A. (2005) · Autophagy

Autophagy in Disease and TherapyGenetics, Aging, and Longevity in Model Organisms

Cited by 792

Necroptosis, necrosis and secondary necrosis converge on similar cellular disintegration features

Berghe, T. V., Vanlangenakker, N., Parthoens, E., Deckers, W., Devos, M., Festjens, N., Guerin, C. J., Brunk, U. T., Declercq, W., & Vandenabeele, P. (2010) · Cell Death & Differentiation

Cell death mechanisms and regulationDeath, Funerary Practices, and Mourning

Cited by 639

Mitochondrial turnover and aging of long-lived postmitotic cells: the mitochondrial-lysosomal axis theory of aging

Terman, A., Kurz, T., Navratil, M., Arriaga, E. A., & Brunk, U. T. (2010) · Antioxidants & Redox Signaling

Autophagy in Disease and TherapyMitochondrial Function and Pathology

Cited by 490

Lipofuscin

Terman, A., & Brunk, U. T. (2004) · The International Journal of Biochemistry & Cell Biology

Autophagy in Disease and TherapyGenetics, Aging, and Longevity in Model Organisms

Cited by 451

Lysosomes in iron metabolism, ageing and apoptosis

Kurz, T., Terman, A., Gustafsson, B., & Brunk, U. T. (2008) · Histochemistry and Cell Biology

Autophagy in Disease and TherapyCalcium signaling and nucleotide metabolism

Cited by 302

Lysosomes and oxidative stress in aging and apoptosis

Kurz, T., Terman, A., Gustafsson, B., & Brunk, U. T. (2008) · Biochimica et Biophysica Acta (BBA) - General Subjects

Autophagy in Disease and TherapyCalcium signaling and nucleotide metabolism

Cited by 287

A novel hypothesis of lipofuscinogenesis and cellular aging based on interactions between oxidative stress and autophagocytosis

Brunk, U. T., Jones, C. B., & Sohal, R. S. (1992) · Mutation Research/DNAging

Autophagy in Disease and TherapyGenetics, Aging, and Longevity in Model Organisms

Cited by 274

Cellular injury induced by oxidative stress is mediated through lysosomal damage

Öllinger, K., & Brunk, U. T. (1995) · Free Radical Biology and Medicine

Bioactive Compounds and Antitumor AgentsRedox biology and oxidative stress

Cited by 243

Autophagy, ageing and apoptosis: The role of oxidative stress and lysosomal iron

Kurz, T., Terman, A., & Brunk, U. T. (2007) · Archives of Biochemistry and Biophysics

Autophagy in Disease and TherapyGenetics, Aging, and Longevity in Model Organisms

Cited by 199

Prevention of oxidant-induced cell death by lysosomotropic iron chelators

Persson, H. L., Yu, Z., Tirosh, O., Eaton, J. W., & Brunk, U. T. (2003) · Free Radical Biology and Medicine

Biochemical Acid Research StudiesRedox biology and oxidative stress

Cited by 185

Intralysosomal iron chelation protects against oxidative stress‐induced cellular damage

Kurz, T., Gustafsson, B., & Brunk, U. T. (2006) · The FEBS Journal

Antioxidant Activity and Oxidative StressRedox biology and oxidative stress

Cited by 175

Oxidized proteins: Mechanisms of removal and consequences of accumulation

Dunlop, R. A., Brunk, U. T., & Rodgers, K. J. (2009) · IUBMB Life

Autophagy in Disease and TherapyUbiquitin and proteasome pathways

Cited by 124

Relocalized redox-active lysosomal iron is an important mediator of oxidative-stress-induced DNA damage

KURZ, T., LEAKE, A., von ZGLINICKI, T., & BRUNK, U. T. (2004) · Biochemical Journal

Redox biology and oxidative stressIron Metabolism and Disorders

Cited by 101

The aging myocardium: roles of mitochondrial damage and lysosomal degradation

Terman, A., & Brunk, U. T. (2005) · Heart, Lung and Circulation

Autophagy in Disease and TherapyMitochondrial Function and Pathology

Cited by 80