Autophagy and aging: The importance of maintaining "clean" cells

The Amyloid Hypothesis of Alzheimer’s Disease: Progress and Problems on the Road to Therapeutics

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Development by Self-Digestion

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A C. elegans mutant that lives twice as long as wild type

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In Vivo Analysis of Autophagy in Response to Nutrient Starvation Using Transgenic Mice Expressing a Fluorescent Autophagosome Marker

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Protein degradation and protection against misfolded or damaged proteins.

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Autophagy Genes Are Essential for Dauer Development and Life-Span Extension in <i>C. elegans</i>

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Proteolysis: from the lysosome to ubiquitin and the proteasome

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Lipofuscin: mechanisms of age-related accumulation and influence on cell function12 1Guest Editor: Rajindar S. Sohal 2This article is part of a series of reviews on “Oxidative Stress and Aging.” The full list of papers may be found on the homepage of the journal.

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Autophagy: in sickness and in health

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Studies on the mechanisms of autophagy: formation of the autophagic vacuole.

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The mitochondrial‐lysosomal axis theory of aging

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Age-related decline in chaperone-mediated autophagy

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Protein Oxidation in Aging and Age‐Related Diseases

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Activation of Chaperone-mediated Autophagy during Oxidative Stress

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The mitochondrial permeability transition initiates autophagy in rat hepatocytes

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Insulin/IGF and target of rapamycin signaling: a TOR de force in growth control.

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Autophagy in the Eukaryotic Cell

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The Molecular Mechanism of Autophagy

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The NAD(P)H Oxidase Homolog Nox4 Modulates Insulin-Stimulated Generation of H2O2 and Plays an Integral Role in Insulin Signal Transduction

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Intracellular Protein Catabolism and its Control During Nutrient Deprivation and Supply

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Does Autophagy Contribute To Cell Death?

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Autophagy Is Activated by Apoptotic Signalling in Sympathetic Neurons: An Alternative Mechanism of Death Execution

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Autophagy and Its Possible Roles in Nervous System Diseases, Damage and Repair

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Uth1p Is Involved in the Autophagic Degradation of Mitochondria

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Increased Life-Span of age -1 Mutants in Caenorhabditis elegans and Lower Gompertz Rate of Aging

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Mechanisms of chaperone-mediated autophagy

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Autophagy and other vacuolar protein degradation mechanisms

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Exogenous amino acids stimulate net muscle protein synthesis in the elderly.

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Insulin regulation of heart function in aging fruit flies

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Genetic and functional changes in mitochondria associated with aging

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Hydrogen peroxide release by mitochondria increases during aging

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A proposed refinement of the mitochondrial free radical theory of aging

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Autophagy, proteasomes, lipofuscin, and oxidative stress in the aging brain

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Protein degradation and aging

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Autophagy: molecular mechanisms, physiological functions and relevance in human pathology

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Autophagy in Yeast: Mechanistic Insights and Physiological Function

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Cell-by-cell scanning of whole mitochondrial genomes in aged human heart reveals a significant fraction of myocytes with clonally expanded deletions

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Neurodegeneration in Normal Brain Aging and Disease

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Lipofuscin Accumulation in Cultured Retinal Pigment Epithelial Cells Causes Enhanced Sensitivity to Blue Light Irradiation

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