Ao, Yan

Astrocyte scar formation aids central nervous system axon regeneration

Anderson, M. A., Burda, J. E., Ren, Y., Ao, Y., O’Shea, T. M., Kawaguchi, R., Coppola, G., Khakh, B. S., Deming, T. J., & Sofroniew, M. V. (2016) · Nature

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STAT3 is a Critical Regulator of Astrogliosis and Scar Formation after Spinal Cord Injury

Herrmann, J. E., Imura, T., Song, B., Qi, J., Ao, Y., Nguyen, T. K., Korsak, R. A., Takeda, K., Akira, S., & Sofroniew, M. V. (2008) · The Journal of Neuroscience

Spinal Cord Injury ResearchCytokine Signaling Pathways and Interactions

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Transformation of nonfunctional spinal circuits into functional states after the loss of brain input

Courtine, G., Gerasimenko, Y., van den Brand, R., Yew, A., Musienko, P., Zhong, H., Song, B., Ao, Y., Ichiyama, R. M., Lavrov, I., et al. (2009) · Nature Neuroscience

Spinal Cord Injury ResearchNerve injury and regeneration

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Astrocyte Kir4.1 ion channel deficits contribute to neuronal dysfunction in Huntington's disease model mice

Tong, X., Ao, Y., Faas, G. C., Nwaobi, S. E., Xu, J., Haustein, M. D., Anderson, M. A., Mody, I., Olsen, M. L., Sofroniew, M. V., et al. (2014) · Nature Neuroscience

Genetic Neurodegenerative DiseasesNeuroscience and Neuropharmacology Research

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Cell-specific and region-specific transcriptomics in the multiple sclerosis model: Focus on astrocytes

Itoh, N., Itoh, Y., Tassoni, A., Ren, E., Kaito, M., Ohno, A., Ao, Y., Farkhondeh, V., Johnsonbaugh, H., Burda, J., et al. (2018) · Proceedings of the National Academy of Sciences

Multiple Sclerosis Research StudiesNeuroinflammation and Neurodegeneration Mechanisms

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Inflammatory Mediators Alter the Astrocyte Transcriptome and Calcium Signaling Elicited by Multiple G-Protein-Coupled Receptors

Hamby, M. E., Coppola, G., Ao, Y., Geschwind, D. H., Khakh, B. S., & Sofroniew, M. V. (2012) · The Journal of Neuroscience

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Reactive astrocytes transduce inflammation in a blood-brain barrier model through a TNF-STAT3 signaling axis and secretion of alpha 1-antichymotrypsin

Kim, H., Leng, K., Park, J., Sorets, A. G., Kim, S., Shostak, A., Embalabala, R. J., Mlouk, K., Katdare, K. A., Rose, I. V. L., et al. (2022) · Nature Communications

Barrier Structure and Function StudiesNeuroinflammation and Neurodegeneration Mechanisms

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Divergent transcriptional regulation of astrocyte reactivity across disorders

Burda, J. E., O’Shea, T. M., Ao, Y., Suresh, K. B., Wang, S., Bernstein, A. M., Chandra, A., Deverasetty, S., Kawaguchi, R., Kim, J. H., et al. (2022) · Nature

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Foreign body responses in mouse central nervous system mimic natural wound responses and alter biomaterial functions

OʼShea, T. M., Wollenberg, A. L., Kim, J. H., Ao, Y., Deming, T. J., & Sofroniew, M. V. (2020) · Nature Communications

Hydrogels: synthesis, properties, applicationsTissue Engineering and Regenerative Medicine

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