Klemsz, Michael J.

Targeted disruption of the PU.1 gene results in multiple hematopoietic abnormalities

McKercher, S. R., Torbett, B. E., Anderson, K. L., Henkel, G. W., Vestal, D. J., Baribault, H., Klemsz, M., Feeney, A. J., Wu, G. E., Paige, C. J., et al. (1996) · The EMBO Journal

Hematopoietic Stem Cell TransplantationT-cell and B-cell Immunology

Cited by 1,130

The macrophage and B cell-specific transcription factor PU.1 is related to the ets oncogene

Klemsz, M. J., McKercher, S. R., Celada, A., Van Beveren, C., & Maki, R. A. (1990) · Cell

Genomics and Chromatin DynamicsT-cell and B-cell Immunology

Cited by 954

The ETS-domain: a new DNA-binding motif that recognizes a purine-rich core DNA sequence.

Karim, F. D., Urness, L. D., Thummel, C. S., Klemsz, M. J., McKercher, S. R., Celada, A., Van Beveren, C., Maki, R. A., Gunther, C. V., & Nye, J. A. (1990) · Genes & Development

Genomics and Chromatin DynamicsProtein Structure and Dynamics

Cited by 499

The Ewing's sarcoma EWS/FLI-1 fusion gene encodes a more potent transcriptional activator and is a more powerful transforming gene than FLI-1.

May, W. A., Lessnick, S. L., Braun, B. S., Klemsz, M., Lewis, B. C., Lunsford, L. B., Hromas, R., & Denny, C. T. (1993) · Molecular and Cellular Biology

Sarcoma Diagnosis and TreatmentChromatin Remodeling and Cancer

Cited by 497

PU.1 recruits a second nuclear factor to a site important for immunoglobulin kappa 3' enhancer activity.

Pongubala, J. M., Nagulapalli, S., Klemsz, M. J., McKercher, S. R., Maki, R. A., & Atchison, M. L. (1992) · Molecular and Cellular Biology

Genomics and Chromatin DynamicsT-cell and B-cell Immunology

Cited by 354

A new pattern for helix–turn–helix recognition revealed by the PU.l ETS–domain–DNA complex

Kodandapani, R., Pio, F., Ni, C.-Z., Piccialli, G., Klemsz, M., McKercher, S., Maki, R. A., & Ely, K. R. (1996) · Nature

Protein Structure and DynamicsGenomics and Chromatin Dynamics

Cited by 315

Effect of PU.1 phosphorylation on interaction with NF-EM5 and transcriptional activation

Pongubala, J., Van Beveren, C., Nagulapalli, S., Klemsz, M., McKercher, Maki, R., & Atchison, M. (1993) · Science

Genomics and Chromatin DynamicsT-cell and B-cell Immunology

Cited by 271

Hematopoietic lineage- and stage-restricted expression of the ETS oncogene family member PU.1

Hromas, R., Orazi, A., Neiman, R., Maki, R., Van Beveran, C., Moore, J., & Klemsz, M. (1993) · Blood

Hematopoietic Stem Cell TransplantationAcute Myeloid Leukemia Research

Cited by 216

PU.1 Expression Delineates Heterogeneity in Primary Th2 Cells

Chang, H.-C., Zhang, S., Thieu, V. T., Slee, R. B., Bruns, H. A., Laribee, R. N., Klemsz, M. J., & Kaplan, M. H. (2005) · Immunity

T-cell and B-cell ImmunologyPsoriasis: Treatment and Pathogenesis

Cited by 159

The transcription factor PU.1 is involved in macrophage proliferation.

Celada, A., Borràs, F. E., Soler, C., Lloberas, J., Klemsz, M., van Beveren, C., McKercher, S., & Maki, R. A. (1996) · The Journal of experimental medicine

Immune cells in cancerGenomics and Chromatin Dynamics

Cited by 152

Regulation of the PU.1 gene by distal elements

Li, Y., Okuno, Y., Zhang, P., Radomska, H. S., Chen, H.-M., Iwasaki, H., Akashi, K., Klemsz, M. J., McKercher, S. R., Maki, R. A., et al. (2001) · Blood

Genomics and Chromatin DynamicsHematopoietic Stem Cell Transplantation

Cited by 110

Activation of Transcription by PU.1 Requires both Acidic and Glutamine Domains

Klemsz, M. J., & Maki, R. A. (1996) · Molecular and Cellular Biology

Genomics and Chromatin DynamicsT-cell and B-cell Immunology

Cited by 93

New Insights on DNA Recognition by ets Proteins from the Crystal Structure of the PU.1 ETS Domain-DNA Complex

Pio, F., Kodandapani, R., Ni, C.-Z., Shepard, W., Klemsz, M., McKercher, S. R., Maki, R. A., & Ely, K. R. (1996) · Journal of Biological Chemistry

Genomics and Chromatin DynamicsProtein Structure and Dynamics

Cited by 81

DNA Methylation and Chromatin Structure Regulate PU.1 Expression

Amaravadi, L., & Klemsz, M. J. (1999) · DNA and Cell Biology

Epigenetics and DNA MethylationGenomics and Chromatin Dynamics

Cited by 44

PU.1 is a lineage-specific regulator of tyrosine phosphatase CD45

Anderson, K. L., Nelson, S. L., Perkin, H. B., Smith, K. A., Klemsz, M. J., & Torbett, B. E. (2001) · Journal of Biological Chemistry

Protein Tyrosine PhosphatasesGenomics and Chromatin Dynamics

Cited by 32

Histone H4 HDAC activity is necessary for expression of the PU.1 gene

Laribee, R. N., & Klemsz, M. J. (2005) · Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression

Histone Deacetylase Inhibitors ResearchGenomics and Chromatin Dynamics

Cited by 11