Taub, Rebecca

A phase 3, randomized, controlled trial of resmetirom in NASH with liver fibrosis

Harrison, S. A., Bedossa, P., Guy, C. D., Schattenberg, J. M., Loomba, R., Taub, R., Labriola, D., Moussa, S. E., Neff, G. W., Rinella, M. E., et al. (2024) · New England Journal of Medicine

Liver Disease Diagnosis and TreatmentLiver physiology and pathology

Cited by 2,084

Liver regeneration: from myth to mechanism

Taub, R. (2004) · Nature Reviews Molecular Cell Biology

Liver physiology and pathologyTissue Engineering and Regenerative Medicine

Cited by 1,567

Liver Failure and Defective Hepatocyte Regeneration in Interleukin-6-Deficient Mice

Cressman, D. E., Greenbaum, L. E., DeAngelis, R. A., Ciliberto, G., Furth, E. E., Poli, V., & Taub, R. (1996) · Science

Liver physiology and pathologyCytokine Signaling Pathways and Interactions

Cited by 1,538

Resmetirom (MGL-3196) for the treatment of non-alcoholic steatohepatitis: a multicentre, randomised, double-blind, placebo-controlled, phase 2 trial

Harrison, S. A., Bashir, M. R., Guy, C. D., Zhou, R., Moylan, C. A., Frias, J. P., Alkhouri, N., Bansal, M. B., Baum, S., Neuschwander-Tetri, B. A., et al. (2019) · The Lancet

Liver Disease Diagnosis and TreatmentLiver physiology and pathology

Cited by 802

Resmetirom for nonalcoholic fatty liver disease: a randomized, double-blind, placebo-controlled phase 3 trial

Harrison, S. A., Taub, R., Neff, G. W., Lucas, K. J., Labriola, D., Moussa, S. E., Alkhouri, N., & Bashir, M. R. (2023) · Nature Medicine

Liver Disease Diagnosis and TreatmentHepatitis C virus research

Cited by 435

Transcriptional control of liver regeneration

Taub, R. (1996) · The FASEB Journal

Liver physiology and pathologyOrgan Transplantation Techniques and Outcomes

Cited by 353

Rapid activation of the stat3 transcription complex in liver regeneration

Cressman, D. E., Diamond, R. H., & Taub, R. (1995) · Hepatology

Liver physiology and pathologyCytokine Signaling Pathways and Interactions

Cited by 314

STAT3 Contributes to the Mitogenic Response of Hepatocytes during Liver Regeneration

Li, W., Liang, X., Kellendonk, C., Poli, V., & Taub, R. (2002) · Journal of Biological Chemistry

Liver physiology and pathologyCytokine Signaling Pathways and Interactions

Cited by 307

Increased toxin-induced liver injury and fibrosis in interleukin-6-deficient mice

Kovalovich, K., DeAngelis, R. A., Li, W., Furth, E. E., Ciliberto, G., & Taub, R. (2000) · Hepatology

Liver physiology and pathologyDrug-Induced Hepatotoxicity and Protection

Cited by 298

CCAAT enhancer- binding protein beta is required for normal hepatocyte proliferation in mice after partial hepatectomy.

Greenbaum, L. E., Li, W., Cressman, D. E., Peng, Y., Ciliberto, G., Poli, V, & Taub, R. (1998) · Journal of Clinical Investigation

Liver physiology and pathologyOrgan Transplantation Techniques and Outcomes

Cited by 270

Discovery of 2-[3,5-Dichloro-4-(5-isopropyl-6-oxo-1,6-dihydropyridazin-3-yloxy)phenyl]-3,5-dioxo-2,3,4,5-tetrahydro[1,2,4]triazine-6-carbonitrile (MGL-3196), a Highly Selective Thyroid Hormone Receptor β Agonist in Clinical Trials for the Treatment of Dyslipidemia

Kelly, M. J., Pietranico-Cole, S., Larigan, J. D., Haynes, N.-E., Reynolds, C. H., Scott, N., Vermeulen, J., Dvorozniak, M., Conde-Knape, K., Huang, K.-S., et al. (2014) · Journal of Medicinal Chemistry

Thyroid Disorders and TreatmentsSynthesis and Characterization of Heterocyclic Compounds

Cited by 231

Rapid activation of post-hepatectomy factor/nuclear factor kappa B in hepatocytes, a primary response in the regenerating liver.

Cressman, D. E., Greenbaum, L. E., Haber, B. A., & Taub, R. (1994) · Journal of Biological Chemistry

Liver physiology and pathologyNF-κB Signaling Pathways

Cited by 224

Effects of Resmetirom on Noninvasive Endpoints in a 36‐Week Phase 2 Active Treatment Extension Study in Patients With NASH

Harrison, S. A., Bashir, M., Moussa, S. E., McCarty, K., Pablo Frias, J., Taub, R., & Alkhouri, N. (2021) · Hepatology Communications

Liver Disease Diagnosis and TreatmentAlcohol Consumption and Health Effects

Cited by 197

Transcriptional Regulatory Signals Define Cytokine-Dependent and -Independent Pathways in Liver Regeneration

Taub, R., Greenbaum, L., & Peng, Y. (1999) · Seminars in Liver Disease

Liver physiology and pathologyOrgan Transplantation Techniques and Outcomes

Cited by 139

Interleukin-6 from intrahepatic cells of bone marrow origin is required for normal murine liver regeneration

Aldeguer, X., Debonera, F., Shaked, A., Krasinkas, A. M., Gelman, A. E., Que, X., Zamir, G. A., Hiroyasu, S., Kovalovich, K. K., Taub, R., et al. (2002) · Hepatology

Liver physiology and pathologyMesenchymal stem cell research

Cited by 138

Interleukin-6-Induced STAT3 and AP-1 Amplify Hepatocyte Nuclear Factor 1-Mediated Transactivation of Hepatic Genes, an Adaptive Response to Liver Injury

Leu, J. I., Crissey, M. A. S., Leu, J. P., Ciliberto, G., & Taub, R. (2001) · Molecular and Cellular Biology

Liver physiology and pathologyCytokine Signaling Pathways and Interactions

Cited by 134

Global Changes in Interleukin–6-Dependent Gene Expression Patterns in Mouse Livers After Partial Hepatectomy

Li, W., Liang, X., Leu, J. I., Kovalovich, K., Ciliberto, G., & Taub, R. (2001) · Hepatology

Liver physiology and pathologyOrgan Transplantation Techniques and Outcomes

Cited by 114

Insights into the Structure and Regulation of Glucokinase from a Novel Mutation (V62M), Which Causes Maturity-onset Diabetes of the Young

Gloyn, A. L., Odili, S., Zelent, D., Buettger, C., Castleden, H. A. J., Steele, A. M., Stride, A., Shiota, C., Magnuson, M. A., Lorini, R., et al. (2005) · Journal of Biological Chemistry

Pancreatic function and diabetesGlycogen Storage Diseases and Myoclonus

Cited by 108

OS-124 Identification and validation of pre-identified morphological baseline features for prediction of fibrosis progression in MAESTRO-NASH

Harrison, S. A., Taub, R., Labriola, D., Zhang, H., Chng, E., Ren, Y., Tai, D., & Schattenberg, J. M. (2024) · Journal of Hepatology

Liver Disease Diagnosis and TreatmentRadiomics and Machine Learning in Medical Imaging

Cited by 3

SAT-214 Using machine learning models to predict baseline fibrosis stage in patients from phase 3 resmetirom trials (MAESTRO-NAFLD and MAESTRO-NASH)

Schattenberg, J. M., Anstee, Q. M., Harrison, S. A., Noureddin, M., Taub, R., Labriola, D., Priel, J., & Padmanabhan, K. (2024) · Journal of Hepatology

Liver Disease Diagnosis and TreatmentRadiomics and Machine Learning in Medical Imaging

Cited by 1