What Should Clinicians Know About Palliative Psychopharmacology?
Open accessAbstract
The nature and scope of palliative psychiatry and associated ethical implications are debated in the literature. This article examines conceptual limitations of extant accounts of palliative psychiatry, with a focus on psychopharmacological practice, and suggests that modifiable and unmodifiable psychiatric illnesses exist on a spectrum along which broader or narrower palliative psychiatric care approaches can be outlined. The article also discusses how these approaches intersect with questions about whether and to what extent psychiatric medications have symptom-reducing or disease-modifying effects. The discussion leads to the conclusion that clinicians are ethically obliged to distinguish among and clearly formulate goals of care in a dynamic and ongoing process of shared decision making with patients.
AI snapshot
Written from the paper’s full text.
TL;DR
This viewpoint argues that existing accounts of palliative psychiatry—those defining it by symptom-reducing versus disease-modifying effects, and those defining it by whether symptom reduction is the goal—are conceptually limited. The author proposes instead that palliative psychopharmacology is best characterized by a focus on quality of life and an acceptance of the *unmodifiable* aspects of illness, which obliges clinicians to formulate goals of care dynamically through shared decision making.
Key findings
- The curative–palliative distinction is orthogonal to the symptomatic–disease-modifying distinction: palliative medications may be either symptomatic or disease modifying depending on context (e.g., palliative chemotherapy is disease modifying but used for symptom/quality-of-life goals).
- Because scientific consensus on whether psychiatric medications are disease modifying is lacking (Ghaemi's criteria for disease modification are not met by evidence on antidepressant relapse prevention, neuroplasticity, early psychosis treatment, or antipsychotic mortality reduction), linking palliative status to disease modification leaves clinicians unable to say with certainty whether an intervention is palliative.
- The author proposes a spectrum of palliative psychiatry with four categories (Table): psychiatric care in palliative medicine; palliative psychiatry (narrow, e.g., hospice care for terminal anorexia nervosa); palliative psychiatry (broad, for severe and persistent mental illness); and palliative psychiatry (very broad, all non-disease-modifying psychiatric care).
- "Unmodifiable" is offered as a broader complement to "futility": aspects of illness may be unmodifiable even absent futility (e.g., cognitive impairment in first-episode schizophrenia), and aspects of even terminal illness remain modifiable palliatively (e.g., reducing acute anxiety with benzodiazepines).
- The author concludes clinicians are ethically obliged to distinguish among and clearly formulate goals of care in a dynamic, ongoing shared decision-making process, an issue bearing on informed consent, nonmaleficence, and hermeneutic justice.
Methods
- Conceptual/normative analysis (viewpoint article) examining the conceptual limitations of extant accounts of palliative psychiatry, focused on psychopharmacological practice.
- Draws on prior definitions of palliative psychiatry (Trachsel et al; Balon et al; Westermair et al), Ghaemi's symptom-reducing versus disease-modifying framework, and the futility concept of Levitt and Buchman; illustrated with examples including ketamine/esketamine for treatment-resistant depression and the public "chemical imbalance" debate.
- No empirical data, sample, or statistical analysis; the paper states it does not intend to settle the disease-modification debate in either direction.
Limitations
- The paper states no formal limitations section; it explicitly notes it does not aim to resolve whether psychiatric medications are disease modifying, only to note that uncertainty complicates labeling interventions palliative or not.
- Evident from the text: this is a single-author conceptual viewpoint without empirical data, and the author acknowledges that where the threshold lies between modifiable and unmodifiable aspects—and thus between curative and palliative characterization—is "a pragmatic matter," leaving the boundary deliberately unspecified.
Model-written summary. Check it against the paper before relying on it.
Integrity signals
Registry
Cites
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Claims the paper makes
0 of 17 cited sources checked · 0 supported · 0 flagged
- Premisecitation
Existing accounts of palliative psychiatry have conceptual limitations, especially concerning psychopharmacological practice.
“Although existing work has attempted to define the boundaries of what constitutes palliative psychiatry, 1,2 many conceptual issues and their ethical implications remain in need of further clarification.”
Quote in the paperNot a substantial claim0 of 2 sources checked- cites [1]
Not checked in the free run.
- cites [2]
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- Interpretationcitation
That evidence, which hints at disease modification, falls short of the standards Ghaemi set.
“There is evidence that antidepressants do reduce risk of future relapse of depression 7 and enhance neuroplasticity and neurogenesis, 8 that early treatment of psychosis modifies long-term course, 9 and that antipsychotics lower mortality, 9 but this body of evidence doesn't meet the criteria laid out by Ghaemi.5”
Quote in the paperSubstantial claim0 of 1 sources checked- cites [5]
Not checked in the free run.
- Premisecitation
Evidence indicates that antipsychotic drugs reduce mortality.
“There is evidence that antidepressants do reduce risk of future relapse of depression 7 and enhance neuroplasticity and neurogenesis, 8 that early treatment of psychosis modifies long-term course, 9 and that antipsychotics lower mortality, 9 but this body of evidence doesn't meet the criteria laid out by Ghaemi.5”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [9]
Not checked in the free run.
- Interpretationcitation
The chemical imbalance controversy showed how much it matters how patients understand their psychiatric treatment.
“The importance of how psychiatric treatment is conceptualized by patients was recently illustrated by the”
Quote in the paperSubstantial claim0 of 1 sources checked- cites [15]
Not checked in the free run.
- Interpretationreasoning
It is misleading to assume that palliative psychopharmacology uses symptom-reducing drugs while curative treatment uses disease-modifying ones.
“As noted, a superficial impression is that palliative psychopharmacology involves the use of symptomatic agents while a curative approach involves disease-modifying agents, but this distinction is misleading.”
Quote in the paperSubstantial claim
- Premisecitation
Evidence indicates that treating psychosis early alters its long-term trajectory.
“There is evidence that antidepressants do reduce risk of future relapse of depression 7 and enhance neuroplasticity and neurogenesis, 8 that early treatment of psychosis modifies long-term course, 9 and that antipsychotics lower mortality, 9 but this body of evidence doesn't meet the criteria laid out by Ghaemi.5”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [9]
Not checked in the free run.
- Interpretationreasoning
A drug given with palliative intent can be either symptom-reducing or disease-modifying, depending on the clinical context and the aim of palliative care.
“The curative-palliative distinction is orthogonal to the symptomatic-disease-modifying distinction, and medications used for palliative purposes may be either symptomatic or disease modifying, depending on the context in which and the purpose for which palliative care is being offered.”
Quote in the paperSubstantial claim - Interpretationreasoning
The scientific dispute about disease modification also concerns how much evidence is needed before one accepts that it is occurring.
“In other words, there is evidence suggestive of disease modification, but the scientific debate on this issue extends to what threshold of evidence is sufficient for us to accept that disease modification is taking place.”
Quote in the paperNot a substantial claim - Interpretationreasoning
Because the evidence is uncertain, it is harder to classify a treatment as disease-modifying or symptom-reducing.
“we only have to note that uncertainty about the evidence complicates labeling an intervention as disease modifying or symptom reducing.”
Quote in the paperNot a substantial claim - Interpretationcitation
When ketamine is used for severe persistent depression with the aim of remission or substantial symptom relief, it usually would not be considered palliative.
“If the goal is remission or significant alleviation of depressive symptoms, this intervention will not typically qualify as palliative.”
Quote in the paperSubstantial claim0 of 1 sources checked- cites [13]
Not checked in the free run.
- Premisecitation
Evidence indicates that antidepressants lower the chance of later depressive relapse.
“There is evidence that antidepressants do reduce risk of future relapse of depression 7 and enhance neuroplasticity and neurogenesis, 8 that early treatment of psychosis modifies long-term course, 9 and that antipsychotics lower mortality, 9 but this body of evidence doesn't meet the criteria laid out by Ghaemi.5”
Quote in the paperSubstantial claim0 of 1 sources checked- cites [7]
Not checked in the free run.
- Interpretationreasoning
Whether care is curative or palliative is a separate axis from whether a medication is symptomatic or disease modifying.
“The curative-palliative distinction is orthogonal to the symptomatic-disease-modifying distinction, and medications used for palliative purposes may be either symptomatic or disease modifying, depending on the context in which and the purpose for which palliative care is being offered.”
Quote in the paperNot a substantial claim - Premisecitation
Evidence indicates that antidepressants increase neuroplasticity and neurogenesis.
“There is evidence that antidepressants do reduce risk of future relapse of depression 7 and enhance neuroplasticity and neurogenesis, 8 that early treatment of psychosis modifies long-term course, 9 and that antipsychotics lower mortality, 9 but this body of evidence doesn't meet the criteria laid out by Ghaemi.5”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [8]
Not checked in the free run.
- Classified as probably not a substantial claim. 22
- May combine two claims. 12
Probably not a substantial claim: may not pass S2 (checkable). May combine two claims.
InterpretationreasoningPsychiatric illness has modifiable and unmodifiable features that lie on a continuum, and palliative psychiatric care can be described in broader or narrower terms along that continuum.
“suggests that modifiable and unmodifiable psychiatric illnesses exist on a spectrum along which broader or narrower palliative psychiatric care approaches can be outlined.”
- Also stated in: § Disease Modification and Symptom Reduction · plain
“In my view, the relevant distinction in palliative psychopharmacology is not etiology vs symptoms or symptoms vs quality of life, but rather modifiable vs unmodifiable aspects of illness in relation to quality of life-aspects that may be either etiological mechanisms or symptoms.”
Quote in the paperNot a substantial claim- Also stated in: § Disease Modification and Symptom Reduction · plain
Probably not a substantial claim: may not pass S2 (checkable). May combine two claims.
InterpretationreasoningContinuing ketamine when it only briefly lifts depression, lowers severity while depression remains, or leaves depression unchanged but makes it more bearable can reasonably be seen as palliative.
“If treatment is continued in the case of such outcomes, these goals can reasonably be considered palliative.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S2 (checkable). May combine two claims.
InterpretationreasoningSuch examples show that palliative goals have several dimensions and can overlap with curative ones.
“These examples serve to illuminate the dimensionality of palliative goals and their overlap with curative goals.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S2 (checkable), S4 (based).
Interpretationnone givenWhich aspects of an illness are unmodifiable is not fixed in advance.
“The unmodifiable aspects of an illness are also not predetermined.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S2 (checkable), S3 (load-bearing).
InterpretationcitationThe same reasoning can apply to other psychotropics, including antidepressants, because different patients may benefit through different mechanisms.
“Similar considerations can also apply to other psychotropics, such as antidepressants for which it is possible that different individuals experience benefit via different pathways.14”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [14]
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Probably not a substantial claim: may not pass S2 (checkable). May combine two claims.
InterpretationreasoningClassic palliative care is easy to identify when the unmodifiable features are clear and stable, but as palliative approaches spread to other settings, what makes care palliative becomes less clear.
“The traditional instances of palliative care are recognizable with reference to treatment contexts wherein the unmodifiable aspects are obvious and stable-as in advanced or terminal physical illness-but as the application of palliative approaches extends to other treatment settings, what is characteristic of palliative care may be less obvious.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S2 (checkable).
InterpretationreasoningFor palliative psychopharmacology, the useful contrast is not etiology versus symptoms or symptoms versus quality of life, but rather which aspects of the illness can be modified and which cannot, in relation to quality of life.
“In my view, the relevant distinction in palliative psychopharmacology is not etiology vs symptoms or symptoms vs quality of life, but rather modifiable vs unmodifiable aspects of illness in relation to quality of life-aspects that may be either etiological mechanisms or symptoms.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S2 (checkable).
InterpretationreasoningWhere the line is drawn between a curative and a palliative clinical approach is a practical decision.
“Where exactly we draw the line on this spectrum between modifiable and unmodifiable aspects of illness-the threshold at which the characterization of our clinical approach begins to shift from curative to palliative-is a pragmatic matter.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S2 (checkable). May combine two claims.
Premisenone givenQuality of life can be improved in several ways: by changing core pathophysiology, by reducing symptoms without modifying disease, or by neither route.
“There are different paths to improving quality of life.Some involve modifying the central pathophysiology of the illness, some involve symptom reduction without disease modification, and some involve neither symptom reduction nor disease modification.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S2 (checkable).
InterpretationreasoningExtremely broad definitions of palliative care can be less useful than narrower ones centered on symptom relief and quality of life in treatment-resistant illness, severe and persistent mental illness, or futility.
“Very broad notions (eg, that routine psychiatric care itself is a form of palliative care) may be unhelpfully broad compared to narrower notions that keep the focus on improving symptoms and quality of life in cases of treatment resistance, SPMI, or futility.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S2 (checkable).
InterpretationreasoningThe presence of an unmodifiable feature does not by itself make the care palliative.
“Conversely, unmodifiability does not necessarily imply that the care provided is automatically palliative.”
Quote in the paperNot a substantial claimMay combine two claims.
InterpretationreasoningIf whether a psychopharmacological treatment is palliative depends on whether it modifies disease, then the absence of scientific consensus means one cannot say with certainty that it is palliative.
“In particular, if we link the palliative status of psychopharmacological treatment to whether or not it is disease modifying, we'd have to acknowledge that there is a lack of scientific consensus on the matter, precluding us from saying with certainty whether the intervention is palliative or not.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S2 (checkable). May combine two claims.
PremisecitationEvidence for disease modification should show fewer future episodes in randomized trials other than randomized discontinuation trials, should not rely only on observational studies, and should demonstrate neuroprotection in living humans.
“For instance, this would require that reduction of future episodes of illness be demonstrated in randomized trial designs other than”
Quote in the paperNot a substantial claim0 of 2 sources checked- cites [5]
Not checked in the free run.
- cites [6]
Not checked in the free run.
Probably not a substantial claim: may not pass S2 (checkable), S4 (based).
Interpretationnone givenFor any given patient, it cannot be known beforehand whether ketamine will improve or worsen quality of life or through what mechanism.
“Whether ketamine treatment increases or decreases quality of life and by what pathway can't be determined in advance for a particular individual.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S2 (checkable). May combine two claims.
InterpretationreasoningClarifying what a treatment aims to change and what it leaves unchanged helps patients grasp their care and keeps clinicians from overlooking causes that might still be modifiable.
“Gaining more clarity on what their treatment seeks to modify and what it leaves unmodified will help patients better understand the nature of their psychiatric care and will ensure that clinicians do not ignore potentially modifiable causes.”
Quote in the paperNot a substantial claim- Rests on an assumption: Some causes of severe, persistent depression are contextual and relational and are not addressed by medication.
May combine two claims.
InterpretationcitationIt is problematic to treat symptom reduction as a curative aim in psychiatry, because in palliative medicine generally, relieving symptoms to improve quality of life is accepted as palliative.
“This characterization of the goal of symptom reduction as curative in psychiatry is problematic, since it doesn't hold for palliative medicine generally, as improving quality of life via targeting symptoms (such as pain or shortness of breath) is a recognizably palliative goal.11”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [11]
Not checked in the free run.
May combine two claims.
PremisecitationMany laypeople wrongly thought depression resulted from low serotonin and that antidepressants corrected serotonin levels, and they were distressed when that account was shown to be false.
“Many individuals in the public who erroneously thought that depression is caused by a serotonergic deficiency and that antidepressants are normalizing serotonin levels were upset to learn that this explanation was fallacious.16”
Quote in the paperSubstantial claim0 of 2 sources checked- cites [15]
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- cites [16]
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Probably not a substantial claim: may not pass S3 (load-bearing).
PremisecitationThe proposed kindling phenomenon in mood disorders posits that every episode strengthens neural pathways, making later episodes more likely.
“There are additional considerations, such as the hypothesized”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [10]
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Probably not a substantial claim: may not pass S2 (checkable).
Interpretationnone givenPalliative care is most essentially present when an aspect of the illness cannot be changed and must be worked around to improve quality of life.
“The essence of palliative care, I suggest, is when we are forced to work around an aspect of the illness to enhance quality of life.”
Quote in the paperNot a substantial claimMay combine two claims.
Interpretationnone givenThe two accounts of palliative psychopharmacology-one based on symptom reduction versus disease modification and one based on treatment goals-each face major limitations.
“As I will explain, both approaches encounter significant limitations.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S2 (checkable). May combine two claims.
InterpretationreasoningUncertainty about where to draw the line affects palliative psychopharmacology and carries ethical implications.
“This demarcation problem brings uncertainty to the practice of palliative psychopharmacology, with attendant ethical consequences.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S1 (asserted), S3 (load-bearing).
PremisecitationOne hypothesis is that early treatment can alter this progression.
“It is hypothesized that early treatment may modify this progression.10”
Quote in the paperNot a substantial claim0 of 1 sources checked- cites [10]
Not checked in the free run.
Probably not a substantial claim: may not pass S2 (checkable).
InterpretationreasoningIt is harder to draw a line between ordinary psychiatric care and palliative psychiatric care than between palliative and general medicine.
“The boundary between routine psychiatric care and palliative psychiatric care has accordingly proven to be more elusive than that between palliative and general medicine.”
Quote in the paperNot a substantial claim- Rests on an assumption: The causes and pathophysiological mechanisms of many psychiatric conditions are still poorly understood, and clinicians have limited ability to alter the mechanisms directly responsible for pathophysiology.
Probably not a substantial claim: may not pass S2 (checkable).
InterpretationreasoningWider and narrower definitions of palliative care each carry distinct benefits and drawbacks.
“Broader or narrower notions of”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S2 (checkable).
InterpretationreasoningIf palliative treatment is described as curative, it wrongly suggests that the causal or etiological mechanisms behind the patient's distress and impairment are being targeted.
“If we present palliative treatment as curative, we generate an erroneous idea that the etiological causes or the causal mechanisms of the distressing and impairing states are being addressed.”
Quote in the paperNot a substantial claimProbably not a substantial claim: may not pass S2 (checkable).
Interpretationnone givenA given episode of care counts as palliative when it prioritizes quality of life and accepts the features of the illness that cannot be changed.
“What distinguishes any particular instance of care as palliative is an emphasis on quality of life and an acceptance of the unmodifiable aspects of an illness.”
Quote in the paperNot a substantial claim
The paper relies on this without support.
The causes and pathophysiological mechanisms of many psychiatric conditions are still poorly understood, and clinicians have limited ability to alter the mechanisms directly responsible for pathophysiology.
“Unlike many chronic conditions in general medicine, the etiology and pathophysiological mechanisms of various psychiatric conditions remain poorly understood, and our ability to modify the mechanisms directly involved in pathophysiology remains limited.”
The paper relies on this without support.
Some causes of severe, persistent depression are contextual and relational and are not addressed by medication.
“At least some of the causes of severe, persistent depression are contextual and relational and not addressed by pharmacological treatment.”
The paper relies on this without support.
The principles of palliative care can be applied to serious and persistent mental illness.
“Palliative psychiatry applies the principles of palliative care to serious and persistent mental illness.”
Claims other papers make about this one
Each is checked against this paper’s own text: does it say what the citing paper says it does?
The implications of the study's findings resonate with recent scholarship on 'palliative psychiatry', which focuses on palliative goals of care, such as improving quality of life and relief of suffering, for patients with serious mental illness who are not necessarily at the end of life.
“the implications of our findings resonate with recent scholarship on ‘palliative psychiatry’, which focuses on palliative goals of care, such as improving quality of life and relief of suffering, for patients with serious mental illness who are not necessarily at the end of life [66, 67].”
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
Each contradiction between two passages listed here was confirmed by an independent check.
In-text citations are offset from the reference list
MinorThe text cites Levitt and Buchman as reference 12, but their work is listed as reference 11; reference 12 is a paper by McIntyre and colleagues. The same one-number offset appears in later citations.
“The notion of "unmodifiable" presented here has similarities to the notion of "futility," which has been applied to palliative psychiatry by Levitt and Buchman.12”
“11. Levitt S, Buchman DZ. Applying futility in psychiatry: a concept whose time has come. J Med Ethics. 2021;47(12):e60. 12. McIntyre RS, Rosenblat JD, Nemeroff CB, et al.”
Cites
McIntyre, R. S., Rosenblat, J. D., Nemeroff, C. B., Sanacora, G., Murrough, J. W., Berk, M., Brietzke, E., Dodd, S., Gorwood, P., Ho, R., et al. (2021) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2020.20081251 · Cited by 731 · see citing works
Correll, C. U., Solmi, M., Croatto, G., Schneider, L. K., Rohani-Montez, S. C., Fairley, L., Smith, N., Bitter, I., Gorwood, P. A. P. M., Taipale, H. T., et al. (2022) · World Psychiatry · doi:10.1002/wps.20994 · Cited by 717 · see citing works
Neural basis of major depressive disorder: Beyond monoamine hypothesis
Boku, S., Nakagawa, S., Toda, H., & Hishimoto, A. (2018) · Psychiatry and Clinical Neurosciences · doi:10.1111/pcn.12604 · Cited by 402 · see citing works
Maintenance or Discontinuation of Antidepressants in Primary Care
Lewis, G., Marston, L., Duffy, L., Freemantle, N., Gilbody, S., Hunter, R., Kendrick, T., Kessler, D., Mangin, D., King, M., et al. (2021) · New England Journal of Medicine · doi:10.1056/nejmoa2106356 · Cited by 192 · see citing works
Trachsel, M., Irwin, S. A., Biller-Andorno, N., Hoff, P., & Riese, F. (2016) · BMC Psychiatry · doi:10.1186/s12888-016-0970-y · Cited by 148 · see citing works
Palliative psychiatry in a narrow and in a broad sense: A concept clarification
Westermair, A. L., Buchman, D. Z., Levitt, S. E., Perrar, K. M., & Trachsel, M. (2022) · Australian & New Zealand Journal of Psychiatry · doi:10.1177/00048674221114784 · Cited by 54 · see citing works
Applying futility in psychiatry: a concept whose time has come
Levitt, S., & Buchman, D. Z. (2021) · Journal of Medical Ethics · doi:10.1136/medethics-2020-106654 · Cited by 40 · see citing works
Symptomatic versus disease‐modifying effects of psychiatric drugs
Ghaemi, S. N. (2022) · Acta Psychiatrica Scandinavica · doi:10.1111/acps.13459 · Cited by 25 · see citing works
Psychopharmacology and Explanatory Pluralism
Aftab, A., & Stein, D. J. (2022) · JAMA Psychiatry · doi:10.1001/jamapsychiatry.2022.0470 · Cited by 24 · see citing works
Self-citationClinical Practice in Palliative Care
Doucet, C. (2008) · Cairn.info · doi:10.3917/psys.082.0121 · Cited by 23 · see citing works
Ghaemi, S. N., & Selker, H. P. (2017) · Journal of Clinical and Translational Science · doi:10.1017/cts.2017.2 · Cited by 23 · see citing works
Maintenance or Discontinuation of Antidepressants in Primary Care
Lewis, G., Marston, L., & Lewis, G. (2021) · New England Journal of Medicine · doi:10.1056/nejmc2117168 · Cited by 16 · see citing works
A Case for Increased Medical Student and Psychiatric Resident Education in Palliative Care
Balon, R., Motlová, L. B., Beresin, E. V., Coverdale, J., Louie, A. K., & Roberts, L. W. (2015) · Academic Psychiatry · doi:10.1007/s40596-015-0479-6 · Cited by 15 · see citing works
Bipolar disorder treatment according to illness trajectory: a systematic review of clinical trials
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Flagged first, then by citations
Cited by
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Palliative Care Psychiatry: Building Synergy Across the Spectrum
Shalev, D., Brenner, K. O., Carlson, R. L., Chammas, D., Levitt, S. E., Noufi, P. E., Robbins-Welty, G. A., & Webb, J. A. (2024) · Current Psychiatry Reports · doi:10.1007/s11920-024-01485-5 · Cited by 22 · see citing works
Palliative psychiatry: research, clinical, and educational priorities
Levitt, S. E., Cooper, R. B., Gupta, M., Kirby, J., Panko, L., Rosenbaum, D., Stajduhar, K., Trachsel, M., Vinoraj, D., Westermair, A. L., et al. (2024) · Annals of Palliative Medicine · doi:10.21037/apm-23-471 · Cited by 12 · see citing works
Stergiopoulos, V., Bastidas-Bilbao, H., Gupta, M., Buchman, D. Z., Stewart, D. E., Rajji, T., Simpson, A. I. F., van Kesteren, M. R., Cappe, V., Castle, D., et al. (2024) · BMC Psychiatry · doi:10.1186/s12888-024-05541-5 · Cited by 5 · see citing works
Palliative care in severe mental disorders: a scoping review
Sousa, A. J. M., Jorge, M. S. B., Lourenço, E. W. R., Fernandes, H. M. A., & de Sousa, M. F. (2024) · BMJ Supportive & Palliative Care · doi:10.1136/spcare-2024-005148 · Cited by 4 · see citing works
Deprescribing as a therapeutic goal in palliative psychiatry
Uvais, N. A., & Rahman, A. M. A. U. (2024) · Indian Journal of Psychiatry · doi:10.4103/indianjpsychiatry.indianjpsychiatry_683_23
Stergiopoulos, V., Bastidas-Bilbao, H., Gupta, M., Buchman, D. Z., Stewart, D. E., Rajji, T. K., Simpson, A. I. F., van Kesteren, M. R., Cappe, V., Castle, D., et al. (2024) · Figshare · doi:10.6084/m9.figshare.25223563
Levitt, S. E., Panko, L., Tsiandoulas, K., Forte, M., Costa, L., & Buchman, D. Z. (2026) · The Canadian Journal of Psychiatry · doi:10.1177/07067437261474291
- Authors
- Aftab, A.
- Affiliations
- Case Western Reserve University (US)
- Corresponding author
- Awais Aftab
- ORCID
- Awais Aftab
- Venue
- AMA Journal of Ethics
- Publisher
- American Medical Association (AMA)
- Published
- 2023-09-01
- Volume
- 25
- Issue
- 9
- Pages
- E710-717
- ISSN
- 1937-7010 (ISSN-L)
- 2376-6980
- OpenAlex
- W4386609171
- Semantic Scholar
- cf2f79813205212892a233c109c44067837aef67
- Cited by
- 7
- References
- 14
- Citations by year
- 2026: 1 · 2024: 6
- FWCI
- 1.79
- Type
- journal article
- Language
- en
- Open access
- diamond
- dx.doi.org
- Locations
- The AMA Journal of Ethic (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Palliative Care and End-of-Life Issues
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Palliative and Oncologic Care
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Ethics and bioethics in healthcare
- Keywords
- palliative psychiatry, psychiatric medication, symptom relief, disease modification, goals of care, shared decision-making, end-of-life care
- MeSH terms
- Decision Making, Shared, Mental Disorders, Humans, Palliative Care, Psychiatry, Psychopharmacology
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