The DOI matches its Crossref record; 12 of the 12 references it cites were found in a registry or an index.
Histological and Ultrastructural Evaluation of the Effects of a Radiofrequency-Based Nonablative Dermal Remodeling Device: A Pilot Study
Abstract
BACKGROUND: Many light- and laser-based systems are used to reduce cutaneous wrinkles, and some have been shown to stimulate dermal collagen production. Using the ThermaCool TC radiofrequency device to treat bovine tendon and human abdominal skin, we documented the cutaneous effects of a radiofrequency-based system for nonablative treatment. OBSERVATIONS: Electron microscopy of bovine tendon treated at varied heat and cooling settings revealed collagen fibrils with increased diameter and loss of distinct borders as deep as 6 mm. Human skin treated at varied heat and cooling settings and examined by means of routine light microscopy demonstrated no significant changes in the epidermis or dermal ground substance immediately after treatment; there was scattered mild perivascular and periadnexal inflammation. Three and 8 weeks after treatment, no observable changes were noted. Ultrastructural analysis, however, disclosed isolated, scattered areas of collagen fibrils with increased diameter and loss of distinct borders. In addition, Northern blot analysis demonstrated an increase in collagen type I messenger RNA steady-state expression. CONCLUSIONS: Our findings suggest that collagen fibril contraction occurs immediately after treatment and gives rise to tissue contraction and thermally mediated wounding, which induces new collagen production.
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Multicenter study of noninvasive radiofrequency for periorbital tissue tightening
Fitzpatrick, R., Geronemus, R., Goldberg, D., Kaminer, M., Kilmer, S., & Ruiz‐Esparza, J. (2003) · Lasers in Surgery and Medicine · doi:10.1002/lsm.10225 · Cited by 365
Self-citationLaser photostimulation of collagen production in healing rabbit achilles tendons
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Pulsed dye laser therapy for sun damaged skin
Zelickson, B. D., Kilmer, S. L., Bernstein, E., Chotzen, V. A., Dock, J., Mehregan, D., & Coles, C. (1999) · Lasers in Surgery and Medicine · doi:10.1002/(sici)1096-9101(1999)25:3<229::aid-lsm7>3.0.co;2-d · Cited by 243
Self-citationEnhanced Elastin and Fibrillin Gene Expression in Chronically Photodamaged Skin
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Self-citationLong-term sun exposure alters the collagen of thepapillary dermis
Bernstein, E. F., Chen, Y. Q., Kopp, J. B., Fisher, L., Brown, D. B., Hahn, P. J., Robey, F. A., Lakkakorpi, J., & Uitto, J. (1996) · Journal of the American Academy of Dermatology · doi:10.1016/s0190-9622(96)80114-9 · Cited by 214
Self-citationSelective non-ablative wrinkle reduction by laser
Bjerring, P., Egevist, H., Clement, M., Heickendorff, L., & Kiernan, M. (2000) · Journal of Cutaneous Laser Therapy · doi:10.1080/14628830050516542 · Cited by 205
Laser photostimulation accelerates wound healing in diabetic rats
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Self-citationA preliminary study of the effects of laser radiation on collagen metabolism in cell culture
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Cited by
Molecular Mechanisms of Dermal Aging and Antiaging Approaches
Shin, J.-W., Kwon, S.-H., Choi, J.-Y., Na, J.-I., Huh, C.-H., Choi, H.-R., & Park, K.-C. (2019) · International Journal of Molecular Sciences · doi:10.3390/ijms20092126 · Cited by 875
Photoaging: mechanisms and repair
Rabe, J. H., Mamelak, A. J., McElgunn, P. J. S., Morison, W. L., & Sauder, D. N. (2006) · Journal of the American Academy of Dermatology · doi:10.1016/j.jaad.2005.05.010 · Cited by 610
Bipolar fractional radiofrequency treatment induces neoelastogenesis and neocollagenesis
Hantash, B. M., Ubeid, A. A., Chang, H., Kafi, R., & Renton, B. (2009) · Lasers in Surgery and Medicine · doi:10.1002/lsm.20731 · Cited by 307
Metadata
- Authors
- Zelickson, B. D., Kist, D., Bernstein, E., Brown, D. B., Ksenzenko, S., Burns, J., Kilmer, S., Mehregan, D., & Pope, K.
- Venue
- Archives of Dermatology
- Publisher
- American Medical Association (AMA)
- Published
- 2004-02-01
- Volume
- 140
- Issue
- 2
- Pages
- 204-9
- ISSN
- 0003-987X (ISSN-L)
- OpenAlex
- W2088402894
- Cited by
- 379
- References
- 12
- FWCI
- 23.88
- Type
- journal article
- Language
- en
- Open access
- closed
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- Zelickson, B. D., Kist, D., Bernstein, E., Brown, D. B., Ksenzenko, S., Burns, J., Kilmer, S., Mehregan, D., & Pope, K. (2004). Histological and Ultrastructural Evaluation of the Effects of a Radiofrequency-Based Nonablative Dermal Remodeling Device: A Pilot Study. Archives of Dermatology. https://doi.org/10.1001/archderm.140.2.204
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