The DOI matches its Crossref record; 7 of the 7 references it cites were found in a registry or an index.
Multiple Facial Angiofibromas and Collagenomas in Patients With Multiple Endocrine Neoplasia Type 1
Abstract
OBJECTIVES: To evaluate patients with multiple endocrine neoplasia type 1 (MEN 1) for cutaneous manifestations. DESIGN: Survey during a 3-year period. SETTING: The National Institutes of Health, a tertiary referral research hospital in Bethesda Md. PATIENTS: A consecutive sample of 32 individuals with previously diagnosed MEN1 who were not preselected for the presence of skin lesions were examined for cutaneous abnormalities. None of the patients or family members were diagnosed as having tuberous sclerosis. INTERVENTIONS: Lesions were identified by clinical appearance, photographed, and confirmed histologically. MAIN OUTCOME MEASURE: To determine the frequency of skin lesions in patients with MEN1. RESULTS: Multiple facial angiofibromas were observed in 28 (88%) of the patients with MEN1, with 16 patients (50%) having 5 or more. Angiofibromas were clinically and histologically identical to those in individuals with tuberous sclerosis. Collagenomas were observed in 23 patients (72%). Also observed were cafe au lait macules in 12 patients (38%), lipomas in 11 patients (34%), confetti-like hypopigmented macules in 2 patients (6%), and multiple gingival papules in 2 patients (6%). CONCLUSIONS: Multiple angiofibromas, collagenomas, lipomas, confetti-like hypopigmented macules and multiple gingival papules are cutaneous manifestations of MEN1 and should be looked for in both family members of patients with MEN1 and individuals with hyperparathyroidism of other MEN1-associated tumors. Multiple angiofibromas can no longer be considered pathognomonic for tuberous sclerosis. The observation of angiofibromas in individuals without tuberous sclerosis necessitates further biochemical testing for MEN1.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Positional Cloning of the Gene for Multiple Endocrine Neoplasia-Type 1
Chandrasekharappa, S. C., Guru, S. C., Manickam, P., Olufemi, S.-E., Collins, F. S., Emmert-Buck, M. R., Debelenko, L. V., Zhuang, Z., Lubensky, I. A., Liotta, L. A., et al. (1997) · Science · doi:10.1126/science.276.5311.404 · Cited by 2,082
A DISTRIBUTION-FREE k-SAMPLE TEST AGAINST ORDERED ALTERNATIVES
JONCKHEERE, A. R. (1954) · Biometrika · doi:10.1093/biomet/41.1-2.133 · Cited by 1,500
Multiple endocrine neoplasia type 1 gene maps to chromosome 11 and is lost in insulinoma
Larsson, C., Skogseid, B., Öberg, K., Nakamura, Y., & Nordenskjöld, M. (1988) · Nature · doi:10.1038/332085a0 · Cited by 1,028
FAMILIAL MULTIPLE ENDOCRINE ADENOMA-PEPTIC ULCER COMPLEX
BALLARD, H. S., FRAME, B., & HARTSOCK, R. J. (1964) · Medicine · doi:10.1097/00005792-196407000-00003 · Cited by 439
Clonality of Parathyroid Tumors in Familial Multiple Endocrine Neoplasia Type 1
Friedman, E., Sakaguchi, K., Bale, A. E., Falchetti, A., Streeten, E., Zimering, M. B., Weinstein, L. S., McBride, W. O., Nakamura, Y., Brandi, M.-L., et al. (1989) · New England Journal of Medicine · doi:10.1056/nejm198907273210402 · Cited by 334
Multiple Endocrine Neoplasia Type I
Marx, S. J., Vinik, A. I., Santen, R. J., Floyd, J. C., Mills, J. L., & Green, J. (1986) · Medicine · doi:10.1097/00005792-198607000-00003 · Cited by 105
Oral fibromatosis in tuberous sclerosis
Lygidakis, N. A., & Lindenbaum, R. H. (1989) · Oral Surgery Oral Medicine Oral Pathology · doi:10.1016/0030-4220(89)90162-x · Cited by 50
Cited by
Northrup, H., Krueger, D. A., Northrup, H., Krueger, D. A., Roberds, S., Smith, K., Sampson, J., Korf, B., Kwiatkowski, D. J., Mowat, D., et al. (2013) · Pediatric Neurology · doi:10.1016/j.pediatrneurol.2013.08.001 · Cited by 1,502
Self-citationGibril, F., Schumann, M., Pace, A., & Jensen, R. T. (2004) · Medicine · doi:10.1097/01.md.0000112297.72510.32 · Cited by 313
Adrenal involvement in multiple endocrine neoplasia type 1: results of 7 years prospective screening
Waldmann, J., Bartsch, D. K., Kann, P. H., Fendrich, V., Rothmund, M., & Langer, P. (2007) · Langenbeck s Archives of Surgery · doi:10.1007/s00423-006-0124-7 · Cited by 104
Griniatsos, J. E., Dimitriou, N., Zilos, A., Sakellariou, S., Evangelou, K., Kamakari, S., Korkolopoulou, P., & Kaltsas, G. (2011) · World Journal of Surgical Oncology · doi:10.1186/1477-7819-9-6 · Cited by 22
Dreijerink, K. M. A., Ozyerli-Goknar, E., Koidl, S., van der Lelij, E. J., van den Heuvel, P., Kooijman, J. J., Biniossek, M. L., Rodenburg, K. W., Nizamuddin, S., & Timmers, H. T. M. (2022) · Epigenetics & Chromatin · doi:10.1186/s13072-022-00461-8 · Cited by 14
Metadata
- Authors
- Darling, T. N.
- Venue
- Archives of Dermatology
- Publisher
- American Medical Association (AMA)
- Published
- 1997-07-01
- Volume
- 133
- Issue
- 7
- Pages
- 853
- ISSN
- 0003-987X (ISSN-L)
- OpenAlex
- W2012589790
- Cited by
- 317
- References
- 7
- FWCI
- 8.61
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Multiple Facial Angiofibromas and Collagenomas in Patients With Multiple Endocrine Neoplasia Type 1. https://app.cochat.ai/papers/10.1001/archderm.1997.03890430067009
- The paper
- Darling, T. N. (1997). Multiple Facial Angiofibromas and Collagenomas in Patients With Multiple Endocrine Neoplasia Type 1. Archives of Dermatology. https://doi.org/10.1001/archderm.1997.03890430067009
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
