Cited by 492Eating Disorders and BehaviorsNutrition, Health and Food BehaviorPersonality Disorders and Psychopathology

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Psychological Treatments of Binge Eating Disorder

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Wilson, G. Terence, Wilfley, Denise E., Agras, W. Stewart, Bryson, Susan W.·2010·Archives of General Psychiatry

DOI 10.1001/archgenpsychiatry.2009.170PMC PMC3757519

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Abstract

CONTEXT: Interpersonal psychotherapy (IPT) is an effective specialty treatment for binge eating disorder (BED). Behavioral weight loss treatment (BWL) and guided self-help based on cognitive behavior therapy (CBTgsh) have both resulted in short-term reductions in binge eating in obese patients with BED. OBJECTIVE: To test whether patients with BED require specialty therapy beyond BWL and whether IPT is more effective than either BWL or CBTgsh in patients with a high negative affect during a 2-year follow-up. DESIGN: Randomized, active control efficacy trial. SETTING: University outpatient clinics. PARTICIPANTS: Two hundred five women and men with a body mass index between 27 and 45 who met DSM-IV criteria for BED. Intervention Twenty sessions of IPT or BWL or 10 sessions of CBTgsh during 6 months. MAIN OUTCOME MEASURES: Binge eating assessed by the Eating Disorder Examination. RESULTS: At 2-year follow-up, both IPT and CBTgsh resulted in greater remission from binge eating than BWL (P < .05; odds ratios: BWL vs CBTgsh, 2.3; BWL vs IPT, 2.6; and CBTgsh vs IPT, 1.2). Self-esteem (P < .05) and global Eating Disorder Examination (P < .05) scores were moderators of treatment outcome. The odds ratios for low and high global Eating Disorder Examination scores were 2.8 for BWL, 2.9 for CBTgsh, and 0.73 for IPT; for self-esteem, they were 2.4 for BWL, 1.9 for CBTgsh, and 0.9 for IPT. CONCLUSIONS: Interpersonal psychotherapy and CBTgsh are significantly more effective than BWL in eliminating binge eating after 2 years. Guided self-help based on cognitive behavior therapy is a first-line treatment option for most patients with BED, with IPT (or full cognitive behavior therapy) used for patients with low self-esteem and high eating disorder psychopathology. TRIAL REGISTRATION: clinicaltrials.gov Identifier: NCT00060762.

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Authors: Wilson, G. T., Wilfley, D. E., Agras, W. S., & Bryson, S. W.
Affiliations: Rutgers, The State University of New Jersey (US)
ORCID: Wilson, G. Terence
Wilfley, Denise E.
Agras, W. Stewart
Venue: Archives of General Psychiatry
Publisher: American Medical Association (AMA)
Published: 2010-01-01
Volume: 67
Issue: 1
Pages: 94
ISSN: 0003-990X (ISSN-L)
DOI: 10.1001/archgenpsychiatry.2009.170
PMC: PMC3757519
OpenAlex: W2149070832
Cited by: 492
References: 37
Citations by year: 2026: 10 · 2025: 24 · 2024: 32 · 2023: 19 · 2022: 28 · 2021: 27 · 2020: 33 · 2019: 25 · 2018: 29 · 2017: 37 · 2016: 36 · 2015: 33 · 2014: 41 · 2013: 29 · 2012: 32
FWCI: 40.51
Type: journal article
Language: en
Open access: green
www.ncbi.nlm.nih.gov
Locations: Archives of General Psychiatry (publishedVersion)
PubMed (publishedVersion)
Europe PMC (PubMed Central) (acceptedVersion)
PubMed Central (acceptedVersion)
Funders: U.S. Public Health Service (R01063862, R01063863, K24 070446, R01064153)
National Institute of Mental Health (R01MH063863, R01MH064153, R01MH063862, K24MH070446)
Topics: Social Sciences › Psychology › Clinical Psychology › Eating Disorders and Behaviors
Health Sciences › Nursing › Nutrition and Dietetics › Nutrition, Health and Food Behavior
Social Sciences › Psychology › Clinical Psychology › Personality Disorders and Psychopathology
Keywords: binge eating disorder, interpersonal psychotherapy, behavioral weight loss, guided self-help, cognitive behavioral therapy, obesity, self-esteem, eating disorder psychopathology, long-term follow-up
MeSH terms: Adult, Behavior Therapy, Female, Follow-Up Studies, Humans, Interpersonal Relations, Longitudinal Studies, Male, Middle Aged, Obesity, Psychiatric Status Rating Scales, Psychotherapy, Self Concept, Self-Help Groups, Weight Loss, Cognitive Behavioral Therapy, Body Mass Index, Treatment Outcome, Diagnostic and Statistical Manual of Mental Disorders, Binge-Eating Disorder

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Psychological Treatments of Binge Eating Disorder

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