The DOI matches its Crossref record; 52 of the 52 references it cites were found in a registry or an index.
National Trends in the Treatment for Depression From 1998 to 2007
Abstract
CONTEXT: The rate of outpatient treatment of depression increased markedly in the United States between 1987 and 1997; it is not known whether this trend has continued. OBJECTIVE: To assess national trends in the outpatient treatment of depression between 1998 and 2007. DESIGN AND SETTING: Analysis of service utilization data from 2 nationally representative surveys of the US household population, the 1998 (n = 22 953) and 2007 (n = 29 370) Medical Expenditure Panel Surveys. PARTICIPANTS: Nationally representative sample of the US household population. MAIN OUTCOME MEASURES: The rate of depression treatment and, among patients who received treatment, the rate of antidepressant medication use, psychotherapy, number of outpatient treatment visits, and expenditures. RESULTS: The rate of outpatient treatment for depression increased from 2.37 per 100 persons in 1998 to 2.88 per 100 persons in 2007 (adjusted odds ratio [AOR], 1.18; 95% confidence interval [CI], 1.03-1.35). The percentage of treated patients who used antidepressants was little changed from 73.8% (1998) to 75.3% (2007) (AOR, 1.14; 95% CI, 0.85-1.51), but the percentage of those receiving psychotherapy declined from 53.6% (1998) to 43.1% (2007) (AOR, 0.71; 95% CI, 0.53-0.95). National expenditures for the outpatient treatment of depression increased from $10.05 billion to $12.45 billion (z = 1.73, P = .08). This was primarily driven by an increase in medication expenditures from $4.59 billion (1998) to $6.60 billion (2007) (z = 2.88, P = .004), which in turn was related to an increase in Medicare expenditures for depression treatment from $0.52 billion (1998) to $2.25 billion (2007) (z = 5.62, P < .001). CONCLUSIONS: Rapid increases in depression treatment from 1987 to 1997 were followed by more modest increases during the following decade. Although there was little change in the proportion of patients receiving antidepressants, treatment with psychotherapy has declined.
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“However, there are several previous studies using the MEPS and their results are comparable with results generated from other sources (42–44).”
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Haun, M. W., Tönnies, J., Brinster, R., Kronsteiner, D., Wensing, M., Szecsenyi, J., Vomhof, M., Icks, A., Wild, B., Hartmann, M., et al. (2021) · Figshare · doi:10.6084/m9.figshare.14545227
Ip, V., Jegatheeswaran, S., Cheema, A. A., FitzGerald, M., Wakif, Z., Thind, J. K., Kyte, S., Yung, S., Raiker, R., Ansar, M. A., et al. (2026) · Cognitive Behaviour Therapy · doi:10.1080/16506073.2026.2623505 · Cited by 2
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Understanding response to treatment in depression: Insights from the Pakistani DIVERGE studyPreprint
Umar, M., Hussain, F., Khizar, B., Khan, I., Khan, F., Cotic, M., Chan, L., Hussain, A., Ali, M. N., Gill, S. A., et al. (2026) · medRxiv · doi:10.64898/2026.04.13.26350625
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Metadata
- Authors
- Marcus, S. C., & Olfson, M.
- Affiliations
- Philadelphia VA Medical Center (US)
- Venue
- Archives of General Psychiatry
- Publisher
- American Medical Association (AMA)
- Published
- 2010-12-06
- Volume
- 67
- Issue
- 12
- Pages
- 1265
- ISSN
- 0003-990X (ISSN-L)
- OpenAlex
- W2118772250
- Cited by
- 312
- References
- 51
- Citations by year
- 2026: 6 · 2025: 8 · 2024: 10 · 2023: 12 · 2022: 11 · 2021: 27 · 2020: 15 · 2019: 26 · 2018: 21 · 2017: 22 · 2016: 26 · 2015: 32 · 2014: 26 · 2013: 28 · 2012: 26
- FWCI
- 30.46
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Archives of General Psychiatry (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Agency for Healthcare Research and Quality (U18HS016097)
- Topics
- Health Sciences › Medicine › Psychiatry and Mental health › Mental Health Treatment and Access
- Health Sciences › Medicine › Pharmacology (medical) › Treatment of Major Depression
- Social Sciences › Psychology › Clinical Psychology › Psychological Treatments and Disorders
- Keywords
- depression, outpatient care, treatment trends, antidepressant use, psychotherapy, treatment costs, Medicare spending, health care utilization, Medical Expenditure Panel Survey, United States, mental health services, managed care
- MeSH terms
- Adult, Aged, Ambulatory Care, Antidepressive Agents, Depression, Major Depressive Disorder, Depressive Disorder, Health Expenditures, Female, Health Resources, Humans, Longitudinal Studies, Male, Middle Aged, Outpatients, Psychotherapy, United States
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