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Meta-analytical Comparison of Voxel-Based Morphometry Studies in Obsessive-Compulsive Disorder vs Other Anxiety Disorders
Abstract
CONTEXT: Whether obsessive-compulsive disorder (OCD) is adequately classified as an anxiety disorder is a matter of considerable debate. OBJECTIVES: To quantitatively compare structural brain changes in OCD and other anxiety disorders using novel voxel-based meta-analytical methods and to generate an online database to facilitate replication and further analyses by other researchers. DATA SOURCES: The PubMed, ScienceDirect, and Scopus databases were searched between 2001 (the date of the first voxel-based morphometry study in any anxiety disorder) and 2009. All voxel-based morphometry studies comparing patients with any anxiety disorder and healthy controls were retrieved. Manual searches were also conducted. Authors were contacted soliciting additional data. STUDY SELECTION: Thirty-seven data sets were identified, of which 26 (including 639 patients with anxiety disorders and 737 healthy controls) met inclusion criteria. DATA EXTRACTION: Coordinates were extracted from clusters of significant gray matter difference between patients and controls. Demographic, clinical, and methodological variables were extracted from each study or obtained from the authors. DATA SYNTHESIS: Patients with anxiety disorders (including OCD) showed decreased bilateral gray matter volumes in the dorsomedial frontal/anterior cingulate gyri. Individuals with OCD had increased bilateral gray matter volumes (vs healthy controls and vs individuals with other anxiety disorders) in the lenticular/caudate nuclei, while patients with other anxiety disorders (mainly panic and posttraumatic stress disorders) had decreased gray matter volumes in the left lenticular nucleus. The findings remained largely unchanged in quartile and jackknife sensitivity analyses. Controlling for potential confounders such as age or antidepressant medication had little impact on the results. CONCLUSIONS: The meta-analysis consistently revealed common as well as distinct neural substrates in OCD and other anxiety disorders. These results have implications for the current debate surrounding the classification of OCD in the DSM-V.
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“Too few studies met our eligibility criteria to perform meta-regressions to explore heterogeneity between disorders, concomitant medication status or therapy type (Radua et al., 2010).”
From Meta-analyses of the neural mechanisms and predictors of response to psychotherapy in depression and anxiety (2018) · cites this paper as Radua et al., 2010
In the citing paper
“There were too few studies that met our eligibility criteria to perform meta-regressions (Radua et al., 2010) to study heterogeneity between disorders, therapies or methodologies (all but one study was task-based).”
From Meta-analyses of the neural mechanisms and predictors of response to psychotherapy in depression and anxiety (2018) · cites this paper as Radua et al., 2010
Citations
Cites
Diagnostic and Statistical Manual of Mental Disorders
Williams, J. B. W., & First, M. B. (2013) · Oxford University Press eBooks · doi:10.1093/acrefore/9780199975839.013.104 · Cited by 109,845
Meta-analysis of Observational Studies in Epidemiology<SUBTITLE>A Proposal for Reporting</SUBTITLE>
Stroup, D. F. (2000) · JAMA · doi:10.1001/jama.283.15.2008 · Cited by 20,623
Wasserman, S. S., Hedges, L. V., & Olkin, I. (1988) · Journal of Educational Statistics · doi:10.2307/1164953 · Cited by 10,377
Voxel-Based Morphometry—The Methods
Ashburner, J., & Friston, K. J. (2000) · NeuroImage · doi:10.1006/nimg.2000.0582 · Cited by 8,676
Cognitive and emotional influences in anterior cingulate cortex
Bush, G., Luu, P., & Posner, M. I. (2000) · Trends in Cognitive Sciences · doi:10.1016/s1364-6613(00)01483-2 · Cited by 6,259
The combination of estimates from different experiments
Cochran, W. G. (1954) · Biometrics · doi:10.2307/3001666 · Cited by 5,380
The cognitive control of emotion
OCHSNER, K., & GROSS, J. (2005) · Trends in Cognitive Sciences · doi:10.1016/j.tics.2005.03.010 · Cited by 4,495
Functional neuroanatomy of emotion: A meta-analysis of emotion activation studies in PET and fMRI
Phan, K. L., Wager, T., Taylor, S. F., & Liberzon, I. (2002) · NeuroImage · doi:10.1006/nimg.2002.1087 · Cited by 3,502
Neurobiology of emotion perception I: the neural basis of normal emotion perception
Phillips, M. L., Drevets, W. C., Rauch, S. L., & Lane, R. (2003) · Biological Psychiatry · doi:10.1016/s0006-3223(03)00168-9 · Cited by 2,173
Neurobiology of emotion perception II: implications for major psychiatric disorders
Phillips, M. L., Drevets, W. C., Rauch, S. L., & Lane, R. (2003) · Biological Psychiatry · doi:10.1016/s0006-3223(03)00171-9 · Cited by 1,736
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Hartmann, A. S., & Wilhelm, S. (2013) · Zeitschrift für Psychiatrie Psychologie und Psychotherapie · doi:10.1024/1661-4747/a000153 · Cited by 6
Modification of spectral features by nonhuman primates
Weiss, D. J., Hotchkin, C. F., & Parks, S. E. (2014) · Behavioral and Brain Sciences · doi:10.1017/s0140525x13004226 · Cited by 6
Soldevila-Matías, P., Albajes‐Eizagirre, A., Raduà, J., García‐Martí, G., Rubio, J. M., Tordesillas‐Gutiérrez, D., Fuentes-Durá, I., Solanes, A., Fortea, L., Oliver, D., et al. (2022) · Revista de Psiquiatría y Salud Mental (English Edition) · doi:10.1016/j.rpsmen.2022.06.004 · Cited by 6
Zeng, J., Yan, J., You, L., Liao, T., Luo, Y., Cheng, B., & Yang, X. (2023) · The International Journal of Neuropsychopharmacology · doi:10.1093/ijnp/pyad009 · Cited by 8
“This method has been widely applied in previous meta-analyses of structural and fMRI studies (Radua et al., 2010; Zeng et al., 2021; Yang et al., 2022).”
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Brezóczki, B., Vékony, T., Pesthy, O., Tóth-Fáber, E., Csigó, K., Farkas, K., & Németh, D. (2023) · Current Opinion in Behavioral Sciences · doi:10.1016/j.cobeha.2023.101326 · Cited by 6
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Shiri, M., Akhavan, S., & Gerami, N. (2012) · InTech eBooks · doi:10.5772/37525 · Cited by 6
Exner, C., Zetsche, U., Martin, V., Rief, W., & Jansen, A. (2012) · Psychiatry Research Neuroimaging · doi:10.1016/j.pscychresns.2011.10.007 · Cited by 6
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Xu, G., Cheng, S., Qu, Y., Cheng, Y., Zhou, J., Li, Z., & Liang, F. (2020) · Medicine · doi:10.1097/md.0000000000019019 · Cited by 5
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BackgroundMethodInfluentialSalto, A. B. R., Santoro, M. L., Hoexter, M. Q., Jackowski, A. P., Pan, P. M., do Rosário, M. C., Belangero, S. I., de Alvarenga, P. G., Doretto, V. F., Fumo, A., et al. (2021) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2021.673595 · Cited by 5
Li, L., Liu, Y., Luo, T., Tao, Y., Zhao, S., Liu, P., Yang, Z., Jiang, Y., Zhang, M., Duan, X., et al. (2025) · BMC Psychiatry · doi:10.1186/s12888-025-06711-9 · Cited by 6
Sazhin, D., Dachs, A., & Smith, D. V. (2025) · European Journal of Neuroscience · doi:10.1111/ejn.70081 · Cited by 8
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Soriano‐Mas, C., & Harrison, B. J. (2018) · Cambridge University Press eBooks · doi:10.1017/9781108164313.009 · Cited by 5
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Hosseinzadeh, M., Azhdehakosh, E., & Valibeygi, A. (2020) · Neuroscience Research Notes · doi:10.31117/neuroscirn.v3i1.39 · Cited by 6
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Zhou, J., Cheng, S., Yang, H., Lan, L., Chen, Y., Xu, G., Yin, Z., Li, Z., & Liu, M. (2020) · Medicine · doi:10.1097/md.0000000000020411 · Cited by 5
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Li, G., Liu, Y., Liu, C., Li, H., Tang, W., & Chen, A. (2025) · Trends in Neuroscience and Education · doi:10.1016/j.tine.2025.100274 · Cited by 5
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Zhang, Q., & Ding, H. (2024) · Frontiers in Neurology · doi:10.3389/fneur.2024.1439939 · Cited by 4
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MethodZhang, D., Teng, C., Xu, Y., Tian, L., Cao, P., Wang, X., Li, Z., Guan, C., & Hu, X. (2024) · Psychological Medicine · doi:10.1017/s0033291724001909 · Cited by 4
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Beaudreau, S. A., Petkus, A. J., Hantke, N. C., & Gould, C. E. (2021) · Cambridge University Press eBooks · doi:10.1017/9781139087469.008 · Cited by 4
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Rao, N. P., & Venkatasubramanian, G. (2015) · Springer eBooks · doi:10.1007/978-3-319-12952-5_9 · Cited by 4
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Figee, M., van den Munckhof, P., Schuurman, R., & Denys, D. A. J. P. (2012) · Springer eBooks · doi:10.1007/978-3-642-30991-5_21 · Cited by 4
Li, Z., Tong, G., Wang, Y., Ruan, H., Zheng, Z., Cheng, J., & Wang, Z. (2024) · The World Journal of Biological Psychiatry · doi:10.1080/15622975.2023.2251057 · Cited by 4
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Tench, C. R., Tănăsescu, R., Jethwa, K. D., & Constantinescu, C. S. (2019) · European Neuropsychopharmacology · doi:10.1016/j.euroneuro.2018.11.452 · Cited by 3
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The utility of electroencephalographic measures in obsession compulsion disorder
Jafadideh, A. T., Ejtehadi, M., Zarei, A., Esfeh, M. A., Yazdi‐Ravandi, S., Matinnia, N., Shamsaei, F., Ahmadpanah, M., Ghaleiha, A., Niyasar, A. R., et al. (2024) · Biomedical Signal Processing and Control · doi:10.1016/j.bspc.2024.107113 · Cited by 2
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Wu, G., Luo, Y., Guo, D., Lv, S., & Yang, J. (2025) · Frontiers in Neuroscience · doi:10.3389/fnins.2025.1556639 · Cited by 2
Towne, J. M., Eslami, V., Barron, D. S., Cavazos, J. E., & Fox, P. T. (2025) · NeuroImage Clinical · doi:10.1016/j.nicl.2025.103908 · Cited by 5
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Ota, M., Kanie, A., Kobayashi, Y., Nakajima, A., Sato, N., & Horikoshi, M. (2020) · Psychiatry Research Neuroimaging · doi:10.1016/j.pscychresns.2020.111124 · Cited by 2
Acar, F., Maumet, C., Heuten, T., Vervoort, M., Bossier, H., Seurinck, R., & Moerkerke, B. (2023) · Neuroinformatics · doi:10.1007/s12021-023-09643-5 · Cited by 2
“& Mataix-Cols, 2009, 2012, 2014; Radua et al., 2010, 2012) is a method for the meta-analysis of neuroimaging data and was first published in 2009.”
Iskander, S., Barahmand, U., Soni, M., Kaur, R., & Arnero, D. (2023) · Psychiatric Annals · doi:10.3928/23258160-20231106-02 · Cited by 2
Wang, R., Lu, L., Gao, Y., Qiu, H., Xu, H., Huang, X., Sweeney, J. A., Gong, Q., & Strawn, J. R. (2024) · CNS Spectrums · doi:10.1017/s1092852924000166 · Cited by 2
“30,31 Briefly, the peak coordinates and corresponding statistical values ( ie , t , z, or p values) from each study were extracted and used to recreate effect-size maps of activation differences between the patients with anxiety disorders and controls.”
Phenome-wide association studies between SERINC2 and neuropsychiatric disorders
Liu, P., Luo, X., Cao, L., Zhang, Y., Ji, J., Wang, X., Wang, K., Pan, X., Yang, R., Tan, Z., et al. (2025) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2024.1420395 · Cited by 2
Fu, X., Yao, Y., An, S., Pan, N., Lin, X., Gong, Q., Deng, H., & Chen, Y. (2025) · Cerebral Cortex · doi:10.1093/cercor/bhaf052 · Cited by 2
Integrated multimodal analysis for high-accuracy anxiety disease subtype classification
Chen, Y., Tang, Y., Ni, Q., Gao, Y., & Wang, C. (2025) · Psychiatry Research Neuroimaging · doi:10.1016/j.pscychresns.2025.111991 · Cited by 2
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Moosavi, S. M., & Ahmadi, M. (2012) · DOAJ (DOAJ: Directory of Open Access Journals) · Cited by 2
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Boedhoe, P. S. W., & van den Heuvel, O. A. (2018) · Neuromethods · doi:10.1007/978-1-4939-7647-8_23 · Cited by 2
Neurobiology of Paediatric Anxiety
Zantvoord, J. B., Lindauer, R., Bakker, M. J., & Boer, F. (2012) · Wiley eBooks · doi:10.1002/9781118315088.ch5 · Cited by 2
Hakami, A. A. A. (2022) · F1000Research · doi:10.12688/f1000research.73530.1 · Cited by 1
Freedman, D., Sawicka, K. M., Oh, J., Main, E., Campbell, K., & Feinstein, A. (2024) · BMJ Open · doi:10.1136/bmjopen-2023-074929 · Cited by 1
Guo, Z., Chen, R., Xiao, S., Sun, S., Chen, G., Chen, P., Tang, X., Huang, L., & Wang, Y. (2025) · Journal of Psychiatric Research · doi:10.1016/j.jpsychires.2025.09.048 · Cited by 1
Shi, R., Dou, Y., He, Y., Luo, M., Yuan, C., Wang, Y., Lan, D., Yang, D., Shen, Y., Su, Y., et al. (2025) · Psychological Medicine · doi:10.1017/s0033291725102699 · Cited by 1
Wang, Z., Liu, Y., Liu, C., & Li, G. (2026) · Brain Sciences · doi:10.3390/brainsci16010078 · Cited by 1
Identification of common spontaneous brain activity alterations across psychiatric disorders
Guo, Z., Tang, X., Xiao, S., Chen, G., Su, T., Wang, A. Y., Chen, R., Chen, C., Yang, Z., Qi, Z., et al. (2026) · Translational Psychiatry · doi:10.1038/s41398-026-03986-8 · Cited by 1
“…stress disorder [PTSD] [18], and AD [19]) or comparisons between two disorders (e.g., SCZ versus BD [20], MDD versus BD [21], OCD versus AD [22]), they consistently suggest that altered spontaneous brain activity frequently involves the frontal lobe, anterior cingulate cortex, insula, and…”
Avram, M.-M., Bayly-Bureau, L., Livingston, N. R., Fusar‐Poli, P., Kempton, M. J., Raduà, J., Mehta, M. A., & Modinos, G. (2026) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2026.106686 · Cited by 1
Li, G., Liu, C., Liu, Y., & Zhang, Y. (2026) · Behavioral and Brain Functions · doi:10.1186/s12993-026-00338-w · Cited by 1
Xiang, J., Ran, J., Zhu, P., Wang, Y., Deng, X., Yang, B., Zhang, L., Chen, X., Guo, J., Liu, J., et al. (2026) · Neuropsychopharmacology · doi:10.1038/s41386-026-02469-0 · Cited by 1
“…enabled conjunction analysis to robustly quantify shared neural patterns between two meta-analytic maps [29], while the “ linear model ” function compares effect sizes between two meta-analyses and generates contrast maps showing regions where abnormal patterns signi fi cantly differed [30].”
N-Acetylcysteine for the Treatment of Obsessive-Compulsive Disorder
Fritzen, F., & Bloch, M. H. (2014) · Current Psychiatry Reviews · doi:10.2174/1573400510666140807005327 · Cited by 1
Koch, K., Rodriguez-Manrique, D., Gigl, S., Ruan, H., Gürsel, D. A., Rus-Oswald, G., Reeß, T. J., & Berberich, G. (2025) · Biological Psychiatry Cognitive Neuroscience and Neuroimaging · doi:10.1016/j.bpsc.2025.01.013 · Cited by 1
Zong, X., Liu, H., & Zhao, X.-Y. (2025) · European journal of medical research · doi:10.1186/s40001-025-02461-2 · Cited by 2
de Wit, S. J., Alonso, P., Schweren, L., Mataix‐Cols, D., Löchner, C., Menchón, J. M., Stein, D. J., Fouché, J., Soriano‐Mas, C., Sato, J. R., et al. (2015) · FOCUS The Journal of Lifelong Learning in Psychiatry · doi:10.1176/appi.focus.130210 · Cited by 1
Self-citationMagnetic resonance imaging in neuromodulation
Downar, J. H., & Davis, K. D. (2015) · Wiley eBooks · doi:10.1002/9781118801086.ch4 · Cited by 1
Stormezand, G. N., Borra, R., Klein, H. C., van Laar, P. J., Boellaard, R., & Dierckx, R. A. J. O. (2016) · Springer eBooks · doi:10.1007/978-3-319-31614-7_9 · Cited by 1
Contents lists available at ScienceDirect
Olbrich, S., Olbrich, H., Adamaszek, M., Jahn, I., Hegerl, U., & Stengler, K. (2011) · Cited by 1
Faculty Opinions recommendation of Intolerance of uncertainty predicts increased striatal volume.
Westenberg, P. M., & Bas‐Hoogendam, J. M. (2017) · Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature · doi:10.3410/f.727715963.793533294 · Cited by 1
García, O., & la Encarnación, A. M. D. (2015) · LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Científicas)
Behavioral Problems in Offspring of Bipolar Mothers
Moosavi, S. M. (2015) · European Journal of Preventive Medicine · doi:10.11648/j.ejpm.20150306.11
Figee, M. (2013) · Data Archiving and Networked Services (DANS) · Cited by 1
Structural Brain Abnormalities in Patients with Panic Disorder
Asami, T., Konishi, J. S., & Hirayasu, Y. (2013) · Anxiety Disorder Research · doi:10.14389/adr.4.37
van Tol, M. (2011)
Tinelli, E., Francia, A., Morreale, M., Pascucci, S., Sbardella, E., Pozzilli, C., & Pantano, P. (2012)
The Neural Crossroads of Psychiatric Illness: An Emerging Target for Brain
Downar, S., & Blumberger, D. M. (2016)
LA RELAZIONE TERAPEUTICA NEI DISTURBI FOBICI E OSSESSIVO-COMPULSIVI
M-Psi, S., & Clínica, P. (2015)
Carlisi, C. O. (2017) · Research Portal (King's College London)
Segrave, R. A., Hendrikse, J. J., & Parkes, L. (2018) · Cambridge University Press eBooks · doi:10.1017/9781108164313.021
Should Obsessive-Compulsive Disorder Be Considered an Anxiety Disorder?
Dubovsky, S. L. (2010) · Journal watch · doi:10.1056/jp201008300000003
Lenze, A. J. P. E. J., & Wetherell, J. L. (2013) · Oxford University Press eBooks · doi:10.1093/med/9780199796816.003.0009
(2010) · Current Opinion in Psychiatry · doi:10.1097/yco.0b013e3283423055
Research Status of the Neural Mechanisms of Mood Disorders and Its Temperament Characteristics
翁, 婷. (2022) · Advances in Social Sciences · doi:10.12677/ass.2022.113104
van Dyck, R., van Balkom, A. J. L. M., van den Heuvel, O. A., & Middeldorp, C. M. (2014) · Wiley eBooks · doi:10.1002/9781118775349.ch67
Gunasekera, B., Davies, C., Blest‐Hopley, G., Wilson, R. P., Busatto, G. F., Crippa, J. A. S., Duran, F., Zuardi, A. W., Veronese, M., Raduà, J., et al. (2022) · Research Square · doi:10.21203/rs.3.rs-1990777/v1
The anatomy of obsessive-compulsive disorderPreprint
Perkes, I. E., Kassem, M. S., Hazell, P., Paxinos, G., Mitchell, P. B., Eapen, V., & Balleine, B. W. (2022) · medRxiv · doi:10.1101/2022.10.06.22280808
Bruin, W. B., Zhutovsky, P., van Wingen, G. A., Bas‐Hoogendam, J. M., Groenewold, N. A., Hilbert, K., Winkler, A. M., Zugman, A., Agosta, F., Åhs, F., et al. (2022) · doi:10.31234/osf.io/exrm9
The contribution of cognitive behavioral therapy to the treatment of obsessive-compulsive disorder
Popa, C. O., & Rus, A. V. (2016) · Romanian Journal of Psychiatry & Psychotherapy · doi:10.37897/rjpp.2016.4.2
“In OCD, short cognitive-behavioral therapy (CBTs) had as a direct effect on brain, neuroanatomical changes consisting of a decrease in thalamic activation correlated with increases in activity of the dorsal anterior cingulate cortex (Dhaka), all these changes are related to a decrease in the symptoms of OCD-specific (…”
BackgroundNeuroanatomy of Obsessive-Compulsive and Related Disorders
Thorsen, A. L., & van den Heuvel, O. A. (2023) · Oxford University Press eBooks · doi:10.1093/oxfordhb/9780190068752.013.7
A Review on Obsessive Compulsive Disorder: Neurotransmitters, Biomarkers and Pharmacotherapy
Singh, M., Majhi, S., & Kataria, R. (2023) · Current Indian Science · doi:10.2174/012210299x256025231010053232 · Cited by 2
Hu, X., Zhang, D., Teng, C., Xu, Y., Tian, L., Cao, P., Wang, X., Li, Z., & Guan, C. (2024) · Research Square · doi:10.21203/rs.3.rs-3800720/v1
Santos, B. F. D. O. (2023) · Digital Library of Theses and Dissertations (Universidade de São Paulo) · doi:10.11606/t.5.2023.tde-02042024-154505
Albukhari, A. F. (2025) · International Journal of Linguistics Applied Psychology and Technology (IJLAPT) · doi:10.69889/ijlapt.v2i05(may).118
“In vivo imaging utilizing [11C]PBR28 positron emission tomography—a marker indicating activated microglia—has shown increased glial activity within the CSTC loop in individuals with OCD when compared to control subjects, providing concrete evidence of central inflammation [16].”
Noninvasive transcranial brain stimulation to treat cognitive aspects of other psychiatric diseases
Downar, J. (2025) · Handbook of behavioral neuroscience · doi:10.1016/b978-0-443-26602-7.00031-2
Avram, M.-M., Bayly-Bureau, L., Livingston, N. R., Fusar‐Poli, P., Kempton, M. J., Raduà, J., Mehta, M. A., & Modinos, G. (2026) · medRxiv · doi:10.64898/2026.01.12.26343386
Dynamics of attention and arousal in healthy and migraine populations
Masson, R. (2020) · theses.fr (ABES) · doi:10.70675/3bb511a1za582z4458za9d7z2bda595f8108
He, J., Wei, X., Wang, X., & Yang, H. (2026) · Asian Journal of Psychiatry · doi:10.1016/j.ajp.2026.104982
Tang, Z., Liang, Y., Tan, X., & Huang, L. (2026) · Neuroscience · doi:10.1016/j.neuroscience.2026.05.013
Nutraceuticals and obsessive-compulsive disorder therapy
Mohammadi, A. H., Amin, N., Tavousi, S. A., Mahabady, M. K., Aschner, M., & Mirzaei, H. (2026) · Advances in neurotoxicology · doi:10.1016/bs.ant.2026.03.001
Ivanov, I., Džinalija, N., Abe, Y., Alonso, P., Ameis, S. H., Arnold, P. D., Baker, J. T., Balachander, S., Banaj, N., Bargalló, N., et al. (2026) · Cortex · doi:10.1016/j.cortex.2026.08.015
Self-citationWei, X., He, J., Li, X., Gou, D., Dong, Q., Wang, X., & Yang, H. (2026) · Biological Psychiatry Cognitive Neuroscience and Neuroimaging · doi:10.1016/j.bpsc.2026.09.004
Zhao, Y., Sun, J., Reheman, B., Bai, X., Zhang, C., Ding, W., Zou, B., Zhang, H., Zhang, Z., & 张宁男楠 (2026) · Frontiers in Neuroimaging · doi:10.3389/fnimg.2026.1917609
Histopathological foundations of behavioral and psychosomatic disorders in animals
Shmayun, S., Утеченко, М. В., Koziy, R., Порошинська, О. А., Huralska, S., Кот, Т. Ф., Yevtukh, L. H., Khomenko, Z., Буднік, Т. С., Leno, Y., et al. (2026) · Regulatory Mechanisms in Biosystems · doi:10.15421/0226140
Metadata
- Authors
- Radua, J., van den Heuvel, O. A., Surguladze, S., & Mataix-Cols, D.
- Venue
- Archives of General Psychiatry
- Publisher
- American Medical Association (AMA)
- Published
- 2010-07-01
- Volume
- 67
- Issue
- 7
- Pages
- 701-11
- ISSN
- 0003-990X (ISSN-L)
- OpenAlex
- W2111531007
- Cited by
- 400
- References
- 104
- Citations by year
- 2026: 14 · 2025: 18 · 2024: 21 · 2023: 21 · 2022: 31 · 2021: 18 · 2020: 22 · 2019: 21 · 2018: 20 · 2017: 33 · 2016: 25 · 2015: 30 · 2014: 30 · 2013: 34 · 2012: 33
- FWCI
- 33.65
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Archives of General Psychiatry (publishedVersion)
- PubMed (publishedVersion)
- Amsterdam UMC (VU Amsterdam) - Institutional Repository (publishedVersion)
- Research Portal (King's College London) (submittedVersion)
- Pure Amsterdam UMC (submittedVersion)
- Data Archiving and Networked Services (DANS) (submittedVersion)
- Topics
- Social Sciences › Psychology › Clinical Psychology › Obsessive-Compulsive Spectrum Disorders
- Social Sciences › Psychology › Experimental and Cognitive Psychology › Anxiety, Depression, Psychometrics, Treatment, Cognitive Processes
- Social Sciences › Psychology › Clinical Psychology › Psychoanalysis and Psychopathology Research
- Keywords
- obsessive-compulsive disorder, anxiety disorders, gray matter volume, brain structural changes, dorsomedial frontal cortex, anterior cingulate cortex, caudate nucleus, lentiform nucleus, panic disorder, post-traumatic stress disorder, DSM-V, voxel-based morphometry
- MeSH terms
- Adult, Anxiety Disorders, Brain, Brain Mapping, Female, Gyrus Cinguli, Humans, Image Processing, Computer-Assisted, Functional Laterality, Male, Obsessive-Compulsive Disorder, Online Systems, Psychiatric Status Rating Scales, Psychometrics, Diagnostic and Statistical Manual of Mental Disorders
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