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Selective Screening for Abdominal Aortic Aneurysms With Physical Examination and Ultrasound
Abstract
Abdominal aortic aneurysm (AAA) is an important cause of preventable death in older persons. Persistently high rupture mortality rates indicate that these deaths can be prevented only by early detection and treatment of AAA. In an effort to develop an effective and efficient program of AAA detection, we selectively screened a high-risk population. Men aged 60 to 75 years with hypertension and/or coronary artery disease were randomly selected from a general medicine clinic and screened with physical examination and ultrasound. Eighteen previously unsuspected aneurysms, 3.6 to 5.9 cm in size (mean, 4.4 cm), were detected in 201 patients, for a prevalence of 9% (95% confidence interval: 4.7% to 13.3%). The specificity and positive predictive value of ultrasound were each 100%. Abdominal palpation detected only half of these aneurysms, but missed none in patients with an abdominal girth less than 100 cm (n = 6). This degree of sensitivity did not occur with "routine" examinations and requires that the examination be directed specifically toward AAA detection. We conclude that undiagnosed AAAs are common in this large subgroup of the clinic population, that ultrasound is an excellent screening test for AAAs, and that physical examination may be adequate for screening thin patients. We recommend that every two or three years persons over the age of 50 years undergo careful abdominal palpation aimed at detecting AAAs, as part of the periodic health examination. We further recommend that obese older men at high risk for AAA have at least one-time screening with abdominal ultrasound, regardless of findings on physical examination.
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Cited by
Wanhainen, A., Verzini, F., Van Herzeele, I., Allaire, E., Bown, M., Cohnert, T., Dick, F., van Herwaarden, J., Karkos, C., Koelemay, M., et al. (2019) · European Journal of Vascular and Endovascular Surgery · doi:10.1016/j.ejvs.2018.09.020 · Cited by 2,326
Wanhainen, A., Van Herzeele, I., Bastos Goncalves, F., Bellmunt Montoya, S., Berard, X., Boyle, J. R., D’Oria, M., Prendes, C. F., Karkos, C. D., Kazimierczak, A., et al. (2024) · European Journal of Vascular and Endovascular Surgery · doi:10.1016/j.ejvs.2023.11.002 · Cited by 1,207
Chaikof, E. L., Brewster, D. C., Dalman, R. L., Makaroun, M. S., Illig, K. A., Sicard, G. A., Timaran, C. H., Upchurch, G. R., & Veith, F. J. (2009) · Journal of Vascular Surgery · doi:10.1016/j.jvs.2009.07.002 · Cited by 732
Advances in diagnostic imaging and overestimations of disease prevalence and the benefits of therapy
Black, W. C., & Welch, H. G. (1993) · New England Journal of Medicine · doi:10.1056/nejm199304293281706 · Cited by 547
Prognosis of Abdominal Aortic Aneurysms
Nevitt, M. P., Ballard, D. J., & Hallett, J. W. (1989) · New England Journal of Medicine · doi:10.1056/nejm198910123211504 · Cited by 485
Metadata
- Authors
- Lederle, F. A.
- Venue
- Archives of Internal Medicine
- Publisher
- American Medical Association
- Published
- 1988-08-01
- Volume
- 148
- Issue
- 8
- Pages
- 1753-1753
- ISSN
- 0003-9926 (ISSN-L)
- OpenAlex
- W2062333114
- Cited by
- 221
- References
- 0
- FWCI
- 10.08
- Type
- journal article
- Language
- en
- Open access
- closed
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- Lederle, F. A. (1988). Selective Screening for Abdominal Aortic Aneurysms With Physical Examination and Ultrasound. Archives of Internal Medicine. https://doi.org/10.1001/archinte.148.8.1753
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.