Advances in diagnostic imaging and overestimations of disease prevalence and the benefits of therapy
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Over the past two decades a vast new armamentarium of diagnostic techniques has revolutionized the practice of medicine. The entire human body can now be imaged in exquisite anatomical detail. Computed tomography (CT), magnetic resonance imaging (MRI), and ultrasonography routinely “section” patients into slices less than a centimeter thick. Abnormalities can be detected well before they produce any clinical signs or symptoms. Undoubtedly, these technological advances have enhanced the physician's potential for understanding disease and treating patients. Unfortunately, these technological advances also create confusion that may ultimately be harmful to patients. Consider the case of prostate cancer. Although the prevalence . . .
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The prevalence of any disease increases with the observer's ability to detect the abnormalities associated with the disease.
“The prevalence of any disease increases with the observer’s ability to detect the abnormalities associated with the disease (32).”
From Adrenal incidentaloma (2020) · cites this paper as [32]
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- Authors
- Black, W. C., & Welch, H. G.
- Affiliations
- Dartmouth College (US)
- Venue
- New England Journal of Medicine
- Publisher
- Massachusetts Medical Society
- Published
- 1993-04-29
- Volume
- 328
- Issue
- 17
- Pages
- 1237-1243
- ISSN
- 0028-4793 (ISSN-L)
- 1533-4406
- OpenAlex
- W2327648646
- Cited by
- 547
- References
- 47
- Citations by year
- 2026: 6 · 2025: 8 · 2024: 7 · 2023: 13 · 2022: 7 · 2021: 13 · 2020: 11 · 2019: 9 · 2018: 14 · 2017: 18 · 2016: 16 · 2015: 23 · 2014: 16 · 2013: 11 · 2012: 15
- FWCI
- 22.14
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- New England Journal of Medicine (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Pulmonary and Respiratory Medicine › Prostate Cancer Diagnosis and Treatment
- Health Sciences › Health Professions › General Health Professions › Healthcare cost, quality, practices
- Health Sciences › Medicine › Radiology, Nuclear Medicine and Imaging › Radiology practices and education
- Keywords
- diagnostic imaging, disease prevalence, prostate cancer, computed tomography, magnetic resonance imaging, ultrasonography, incidental finding
- MeSH terms
- Aged, Breast Neoplasms, Decision Making, Diagnostic Imaging, Female, Humans, Male, Middle Aged, Neoplasms, Thyroid Neoplasms, Bias, Prevalence, Aortic Aneurysm, Abdominal
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