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Compliance Declines Between Clinic Visits
Abstract
Adherence to prescribed drug dosing regimens declined substantially during the interval between clinic visits and drug level tests. Using microelectronic monitors to observe pill-taking habits, 20 patients averaged 88% compliance before and 86% compliance after the visit, but this dropped to 67% compliance a month later. These data indicate that spot drug levels do not represent long-term "steady-state" drug serum concentrations.
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Citations
Cited by
Osterberg, L., & Blaschke, T. (2005) · New England Journal of Medicine · doi:10.1056/nejmra050100 · Cited by 7,974
A systematic review of the associations between dose regimens and medication compliance
Claxton, A. J., Cramer, J., & Pierce, C. (2001) · Clinical Therapeutics · doi:10.1016/s0149-2918(01)80109-0 · Cited by 2,388
Self-citationMedication adherence measures: An overview
Lam, W. Y., & Fresco, P. (2015) · BioMed Research International · doi:10.1155/2015/217047 · Cited by 1,308
Farmer, K. C. (1999) · Clinical Therapeutics · doi:10.1016/s0149-2918(99)80026-5 · Cited by 889
Adherence in Hypertension: A Review of Prevalence, Risk Factors, Impact, and Management
Burnier, M., & Egan, B. M. (2019) · Circulation Research · doi:10.1161/circresaha.118.313220 · Cited by 878
Metadata
- Authors
- Cramer, J. A.
- Venue
- Archives of Internal Medicine
- Publisher
- American Medical Association (AMA)
- Published
- 1990-07-01
- Volume
- 150
- Issue
- 7
- Pages
- 1509
- ISSN
- 0003-9926 (ISSN-L)
- OpenAlex
- W2085211662
- Cited by
- 405
- References
- 0
- FWCI
- 11.22
- Type
- journal article
- Language
- en
- Open access
- closed
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Cite CoChat for the checks on this page, and the paper for its own findings.
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- CoChat. (2026). Citation check: Compliance Declines Between Clinic Visits. https://app.cochat.ai/papers/10.1001/archinte.150.7.1509
- The paper
- Cramer, J. A. (1990). Compliance Declines Between Clinic Visits. Archives of Internal Medicine. https://doi.org/10.1001/archinte.150.7.1509
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
