The DOI matches its Crossref record; 7 of the 7 references it cites were found in a registry or an index.
The Effects of Improved Glycemic Control on Complications in Type 2 Diabetes
Abstract
Type 2 diabetes is 8 to 10 times more common than type 1 diabetes, but no single large trial has established that improved glycemic control can prevent complications in type 2 diabetes. We have reviewed the results of the existing epidemiologic and clinical trial studies and have arrived at the following conclusions: (1) Strong evidence exists that improved glycemic control is effective at lessening the risks of retinopathy, neuropathy, and nephropathy in type 2 diabetes. (2) The evidence about the effect on coronary heart disease is limited and equivocal. (3) The hypoglycemic risk from improved glycemic control is significantly less in type 2 diabetes than in type 1, and weight gain seems to be modest. In conclusion, although glycemic goals should be individualized based on several clinical factors, most patients with type 2 diabetes would probably benefit from glucose lowering to a hemoglobin A1c level between 7% and 8%.
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Cites
U.K. Prospective Diabetes Study Group (1995) · Diabetes · doi:10.2337/diab.44.11.1249 · Cited by 1,923
Young, M. J., Boulton, A. J. M., Macleod, A. F., Williams, D. R. R., & Sonksen, P. H. (1993) · Diabetologia · doi:10.1007/bf00400697 · Cited by 1,502
Dyck, P. J., Kratz, K. M., Karnes, J. L., Litchy, W. J., Klein, R., Pach, J. M., Wilson, D. M., O'Brien, P. C., & Melton, L. J. (1993) · Neurology · doi:10.1212/wnl.43.4.817 · Cited by 1,482
Efficacy of Metformin in Patients with Non-Insulin-Dependent Diabetes Mellitus
DeFronzo, R. A., & Goodman, A. M. (1995) · New England Journal of Medicine · doi:10.1056/nejm199508313330902 · Cited by 1,368
Abraira, C., Colwell, J. A., Nuttall, F. Q., Sawin, C. T., Nagel, N. J., Comstock, J. P., Emanuele, N. V., Levin, S. R., Henderson, W., Lee, H. S., et al. (1995) · Diabetes Care · doi:10.2337/diacare.18.8.1113 · Cited by 355
Comparison of insulin regimens in patients with non-insulin-dependent diabetes mellitus
Yki-Järvinen, H., Kauppila, M., Kujansuu, E., Lahti, J., Marjanen, T., Niskanen, L., Rajala, S., Ryysy, L., Salo, S., Seppälä, P., et al. (1992) · New England Journal of Medicine · doi:10.1056/nejm199211123272005 · Cited by 324
Henry, R. R., Gumbiner, B., Ditzler, T., Wallace, P., Lyon, R., & Glauber, H. S. (1993) · Diabetes Care · doi:10.2337/diacare.16.1.21 · Cited by 227
Cited by
Meta-analysis: glycosylated hemoglobin and cardiovascular disease in diabetes mellitus
Selvin, E., Marinopoulos, S., Berkenblit, G., Rami, T., Brancati, F. L., Powe, N. R., & Golden, S. H. (2004) · Annals of Internal Medicine · doi:10.7326/0003-4819-141-6-200409210-00007 · Cited by 1,657
Hermansen, K., Davies, M., Derezinski, T., Martinez Ravn, G., Clauson, P., Home, P., & on behalf of the Levemir Treat-to-Target Study Group (2006) · Diabetes Care · doi:10.2337/dc05-1365 · Cited by 627
Anti-diabetic effect of cinnamon extract on blood glucose in db/db mice
Kim, S. H., Hyun, S. H., & Choung, S. Y. (2006) · Journal of Ethnopharmacology · doi:10.1016/j.jep.2005.08.059 · Cited by 503
Haghighatpanah, M., Nejad, A. S. M., Haghighatpanah, M., Thunga, G., & Mallayasamy, S. (2018) · Osong Public Health and Research Perspectives · doi:10.24171/j.phrp.2018.9.4.05 · Cited by 186
Increased QT dispersion during hypoglycaemia in patients with type 2 diabetes mellitus
Landstedt‐Hallin, L., Englund, A., Adamson, U., & Lins, P. ‐. (1999) · Journal of Internal Medicine · doi:10.1046/j.1365-2796.1999.00528.x · Cited by 141
Metadata
- Authors
- Gaster, B., & Hirsch, I. B.
- Venue
- Archives of Internal Medicine
- Publisher
- American Medical Association (AMA)
- Published
- 1998-01-26
- Volume
- 158
- Issue
- 2
- Pages
- 134
- ISSN
- 0003-9926 (ISSN-L)
- OpenAlex
- W2037417878
- Cited by
- 228
- References
- 7
- FWCI
- 13.49
- Type
- journal article
- Language
- en
- Open access
- closed
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- Gaster, B., & Hirsch, I. B. (1998). The Effects of Improved Glycemic Control on Complications in Type 2 Diabetes. Archives of Internal Medicine. https://doi.org/10.1001/archinte.158.2.134
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
