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Cited by 202Diabetes, Cardiovascular Risks, and LipoproteinsDiabetes Management and ResearchHealthcare Systems and Public Health

The DOI matches its Crossref record; 22 of the 22 references it cites were found in a registry or an index.

Major Factors in the Development of Diabetes Mellitus in 10,000 Men

Medalie, Jack H.·1975·Archives of Internal Medicine
DOI 10.1001/archinte.135.6.811
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Abstract

The average annual incidence of diabetes among 8,688 adult men followed up for five years was 8.0/1,000 with Asian, African and Israeli-born having higher rates than European-born. Multivariate analysis of the findings suggested the following: the most significant variables associated with the development of diabetes are overweight and peripheral vascular disease; the high incidence of diabetes in immigrants from Asia and Africa might be an example of Neel's "thrifty genotype" or failure of adaptation to relatively rapid environmental changes; serum cholesterol level, blood pressure, uric acid level, and education were important also; and the probability of developing diabetes within five years rises from 17/1,000 (when the major variables are low or absent) to 450/1,000 (when they are high and present). This has important clinical implications.

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Crossref · 10.1001/archinte.1975.00330060055007

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Metadata

Authors
Medalie, J. H.
Corresponding author
Medalie, Jack H.
Venue
Archives of Internal Medicine
Publisher
American Medical Association (AMA)
Published
1975-06-01
Volume
135
Issue
6
Pages
811
ISSN
0003-9926 (ISSN-L)
DOI
10.1001/archinte.135.6.811
OpenAlex
W1999024460
Cited by
202
References
22
Citations by year
2026: 2 · 2024: 2 · 2023: 3 · 2022: 3 · 2021: 4 · 2019: 1 · 2018: 4 · 2017: 4 · 2016: 5 · 2015: 1 · 2014: 3 · 2013: 6 · 2012: 5
FWCI
4.21
Type
journal article
Language
en
Open access
closed
Locations
  • Archives of Internal Medicine (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes, Cardiovascular Risks, and Lipoproteins
  • Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Diabetes Management and Research
  • Health Sciences › Medicine › Epidemiology › Healthcare Systems and Public Health
Keywords
diabetes mellitus, incidence, risk factors, overweight, peripheral vascular disease, immigrant health, Asian immigrants, African immigrants, thrifty genotype, serum cholesterol, blood pressure, uric acid, educational attainment, men
MeSH terms
Adaptation, Physiological, Adult, Africa, Northern, Age Factors, Asia, Blood Glucose, Blood Pressure, Body Height, Body Weight, Cholesterol, Diabetes Mellitus, Educational Status, Ethnicity, Europe, Genotype, Glucose Tolerance Test, Humans, Intermittent Claudication, Israel, Male, Middle Aged, Prospective Studies, Risk, Uric Acid, Vascular Diseases

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CoChat. (2026). Citation check: Major Factors in the Development of Diabetes Mellitus in 10,000 Men. https://app.cochat.ai/papers/10.1001/archinte.135.6.811
The paper
Medalie, J. H. (1975). Major Factors in the Development of Diabetes Mellitus in 10,000 Men. Archives of Internal Medicine. https://doi.org/10.1001/archinte.135.6.811