Coccidioidomycosis in renal replacement therapy
Abstract
The potential risk of coccidioidomycosis has led to concern about the advisability of maintaining renal transplantation programs in endemic areas. We reviewed the charts of 721 patients undergoing dialysis and 260 renal transplant recipients in Arizona to determine the incidence, risk factors, and clinical course of coccidioidomycosis in these immunosuppressed populations. Symptomatic infection occurred in six (0.83%) patients undergoing dialysis and 18 (6.9%) transplant recipients. Male sex and blood type B predisposed to dissemination. Urine cultures for fungus were important diagnosis aids. Four of six patients with infection limited to the thorax and five of 18 patients with dissemination remained alive after seven months to 7 1/2 years. Although the rate of dissemination (75%) and mortality (63%) from coccidioidomycosis were high, the incidence of infection was low and does not preclude renal transplantation in Arizona. Those who have received transplants elsewhere should be advised not to move or to visit areas endemic for coccidioidomycosis.
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The relationship between race and symptomatic coccidioidomycosis was not seen in renal transplant recipients with coccidioidomycosis.
“but this relationship was not seen in the renal transplant recipients with coccidioidomycosis [158].”
From Race and ethnicity: Risk factors for fungal infections? (2023) · cites this paper as [158]
Cites
A Generalized Wilcoxon Test for Comparing Arbitrarily Singly-Censored Samples
Gehan, E. A. (1965) · Biometrika · doi:10.1093/biomet/52.1-2.203 · Cited by 3,407 · see citing works
Determination of prognosis in chronic disease, illustrated by systemic lupus erythematosus
Merrell, M., & SHULMAN, L. E. (1955) · Journal of Chronic Diseases · doi:10.1016/0021-9681(55)90018-7 · Cited by 560 · see citing works
TUCSON EPIDEMIOLOGIC STUDY OF OBSTRUCTIVE LUNG DISEASES
Lebowitz, M. D., & Burrows, B. A. (1975) · American Journal of Epidemiology · doi:10.1093/oxfordjournals.aje.a112142 · Cited by 241 · see citing works
Fungal Infection Following Renal Transplantation
Gallis, H. A. (1975) · Archives of Internal Medicine · doi:10.1001/archinte.1975.00330090035004 · Cited by 147 · see citing works
Symptomatic Coccidioidomycosis following a Severe Natural Dust Storm
Williams, P. L., Sable, D. L., Mendez, P., & Smyth, L. T. (1979) · CHEST Journal · doi:10.1378/chest.76.5.566 · Cited by 100 · see citing works
Factors Affecting the Frequency of Infection in Renal Transplant Recipients
Murphy, J. (1976) · Archives of Internal Medicine · doi:10.1001/archinte.1976.03630060022006 · Cited by 71 · see citing works
Association of abo blood group and outcome of coccidioidal infection
Deresinski, S. C., Pappagianis, D., & Stevens, D. A. (1979) · Medical Mycology · doi:10.1080/00362177985380381 · Cited by 56 · see citing works
THE PRESENT STATUS OF VACCINATION AGAINST COCCIDIOIDOMYCOSIS IN MAN
Pappagianis, D., & Levine, H. B. (1975) · American Journal of Epidemiology · doi:10.1093/oxfordjournals.aje.a112131 · Cited by 39 · see citing works
NOMENCLATURE FOR FACTORS OF THE HLA SYSTEM-1977
Albert, E. D., Amos, D. B., Bodmer, W. F., et al. (1978) · Transplantation · doi:10.1097/00007890-197805000-00011 · Cited by 13 · see citing works
Cryptococcosis in renal transplant patients.
Tipple, M. A., Haywood, H., Shadomy, S., et al. (1977) · PubMed · Cited by 6 · see citing works
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Influence of host genetics on the severity of coccidioidomycosis
Louie, L., Ng, S., Hajjeh, R., Johnson, R., Vugia, D., Werner, S. B., Talbot, R., & Klitz, W. (1999) · Emerging Infectious Diseases · doi:10.3201/eid0505.990508 · Cited by 99 · see citing works
Wiederhold, N. P., Najvar, L. K., Jaramillo, R., Olivo, M., Birch, M., Law, D., Rex, J. H., Catano, G., & Patterson, T. F. (2018) · Antimicrobial Agents and Chemotherapy · doi:10.1128/aac.00999-18 · Cited by 80 · see citing works
Race and ethnicity: Risk factors for fungal infections?
Jenks, J. D., Aneke, C. I., Al-Obaidi, M. M., Egger, M., Garcia, L., Gaines, T., Hoenigl, M., & Thompson, G. R. (2023) · PLOS Pathogens · doi:10.1371/journal.ppat.1011025 · Cited by 55 · see citing works
- Authors
- Cohen, I. M.
- Affiliations
- University of Arizona (US)
- Corresponding author
- Cohen, Irvin M.
- Venue
- Archives of Internal Medicine
- Publisher
- American Medical Association (AMA)
- Published
- 1982-03-01
- Volume
- 142
- Issue
- 3
- Pages
- 489
- ISSN
- 0003-9926 (ISSN-L)
- OpenAlex
- W2039603262
- Cited by
- 163
- References
- 10
- Citations by year
- 2025: 4 · 2024: 3 · 2023: 4 · 2022: 1 · 2021: 5 · 2020: 5 · 2019: 4 · 2018: 4 · 2017: 2 · 2016: 3 · 2015: 2 · 2014: 6 · 2013: 5
- FWCI
- 2.67
- Type
- journal article
- Language
- en
- Open access
- closed
- Locations
- Archives of Internal Medicine (publishedVersion)
- PubMed (publishedVersion)
- Topics
- Health Sciences › Medicine › Epidemiology › Fungal Infections and Studies
- Health Sciences › Medicine › Epidemiology › Pneumocystis jirovecii pneumonia detection and treatment
- Health Sciences › Medicine › Microbiology › Actinomycetales infections and treatment
- Keywords
- coccidioidomycosis, kidney transplantation, hemodialysis, immunosuppression, disseminated fungal infection, risk factors, blood type B, male sex, urine culture, endemic fungal infection, Arizona, mortality
- MeSH terms
- ABO Blood-Group System, Adolescent, Adult, Arizona, Coccidioidomycosis, Female, Renal Dialysis, Humans, Immunosuppression Therapy, Male, Middle Aged, Risk, Sex Factors, Kidney Transplantation
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