The DOI matches its Crossref record; 13 of the 13 references it cites were found in a registry or an index.
Cholinergic-Anticholinergic Antagonism in Parkinsonism
Abstract
THE LIMITEDclinical efficacy of the belladonna alkaloids in the treatment of parkinsonism was first noted a century ago by Charcot and his student, Ordenstein.1Although an extraordinary number of pharmacological agents have been tried at various times in the 100 years which have elapsed since this early therapeutical trial, few have been found which can equal the effect of atropine, scopolamine, or stramonium, and none can truly be said to be appreciably more effective. The clinical use of these alkaloids in treating extrapyramidal disorders has been entirely based on empirical observation and was well established long before their fundamental mechanism of action as acetylcholine antagonists was understood. Thus, it seems significant that virtually all known medicinal preparations of botanical origin have been used in parkinsonism over the past century but that only those containing one or more of the belladonna alkaloids achieved enduring and widespread acceptance. Recognition of
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Cites
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DOPAMINE (3-HYDROXYTYRAMINE) AND BRAIN FUNCTION
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Acetylcholine synthesis in different regions of the central nervous system
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Further evidence for the presence of nigro‐neostriatal dopamine neurons in the rat
Andén, N., Dahlström, A., Fuxe, K., & Larsson, K. (1965) · American Journal of Anatomy · doi:10.1002/aja.1001160117 · Cited by 236
Choline acetylase in the central nervous system of man and some other mammals
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PRESENT VIEWS ON THE MODE OF ACTION OF ACETYLCHOLINE IN THE CENTRAL NERVOUS SYSTEM
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The “caudate-spindle” I. electrophysiological properties
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Cited by
Bernheimer, H., Birkmayer, W., Hornykiewicz, O., Jellinger, K., & Seitelberger, F. (1973) · Journal of the Neurological Sciences · doi:10.1016/0022-510x(73)90175-5 · Cited by 2,651
The scientific and clinical basis for the treatment of Parkinson disease (2009)
Olanow, C. W., Stern, M. B., & Sethi, K. (2009) · Neurology · doi:10.1212/wnl.0b013e3181a1d44c · Cited by 908
The Dopamine Hypothesis of Schizophrenia: A Review*
Meltzer, H. Y., & Stahl, S. M. (1976) · Schizophrenia Bulletin · doi:10.1093/schbul/2.1.19 · Cited by 883
Presynaptic regulation of neurotransmitter release in the brain: Facts and hypothesis
Chesselet, M.-F. (1984) · Neuroscience · doi:10.1016/0306-4522(84)90058-7 · Cited by 577
The cholinergic system and Parkinson disease
Bohnen, N. I., & Albin, R. L. (2011) · Behavioural Brain Research · doi:10.1016/j.bbr.2009.12.048 · Cited by 566
Metadata
- Authors
- Duvoisin, R. C.
- Venue
- Archives of Neurology
- Publisher
- American Medical Association (AMA)
- Published
- 1967-08-01
- Volume
- 17
- Issue
- 2
- Pages
- 124-136
- ISSN
- 0003-9942 (ISSN-L)
- OpenAlex
- W2018998508
- Cited by
- 342
- References
- 13
- FWCI
- 19.85
- Type
- journal article
- Language
- en
- Open access
- closed
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Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
