The DOI matches its Crossref record.
Prolonged Epileptic Seizures in Primates: Ischemic Cell Change and Its Relation to Ictal Physiological Events
Abstract
Neuronal alterations typical of ischemic cell change were seen in the brains of ten adolescent baboons after generalized seizures, lasting 82 to 299 minutes, induced by bicuculline. These changes involved the neocortex (diffusely, in all ten cases, with some accentuation occipitally), the cerebellum (Purkinje and basket cells, predominantly in the arterial boundary zone) and the hippocampus (hi and h3-5sometimes asymmetrically). The brain damage apparently originated during the second phase of the seizure when hyperpyrexia, mild arterial hypotension, mild systemic hypoxia, and acidosis were characteristically, and severe hypoglycemia occasionally, seen. Cerebellar damage was related to hyperpyrexia and arterial hypotension. Numerous factors (including the cerebral epileptic activity) interacted to produce the cortical damage.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cited by
It’s time to revise the definition of status epilepticus
Lowenstein, D. H., Bleck, T., & Macdonald, R. L. (1999) · Epilepsia · doi:10.1111/j.1528-1157.1999.tb02000.x · Cited by 805
Ben-Ari, Y., Tremblay, E., Riche, D., Ghilini, G., & Naquet, R. (1981) · Neuroscience · doi:10.1016/0306-4522(81)90193-7 · Cited by 649
Biological differences between ischemia, hypoglycemia, and epilepsy
Auer, R. N., & Siesjo, B. K. (1988) · Annals of Neurology · doi:10.1002/ana.410240602 · Cited by 331
Non-convulsive status epilepticus in adults: clinical forms and treatment
Meierkord, H., & Holtkamp, M. (2007) · The Lancet Neurology · doi:10.1016/s1474-4422(07)70074-1 · Cited by 265
Degeneration of hippocampal CA3 pyramidal cells induced by intraventricular kainic acid
Nadler, J. V., Perry, B. W., Gentry, C., & Cotman, C. W. (1980) · Journal of Comparative Neurology · doi:10.1002/cne.901920209 · Cited by 255
Metadata
- Authors
- Meldrum, B. S.
- Venue
- Archives of Neurology
- Publisher
- American Medical Association (AMA)
- Published
- 1973-01-01
- Volume
- 28
- Issue
- 1
- Pages
- 10
- ISSN
- 0003-9942 (ISSN-L)
- OpenAlex
- W2089274977
- Cited by
- 524
- References
- 0
- FWCI
- 7.77
- Type
- journal article
- Language
- en
- Open access
- closed
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
How to cite
Cite CoChat for the checks on this page, and the paper for its own findings.
- This page
- CoChat. (2026). Citation check: Prolonged Epileptic Seizures in Primates: Ischemic Cell Change and Its Relation to Ictal Physiological Events. https://app.cochat.ai/papers/10.1001/archneur.1973.00490190028002
- The paper
- Meldrum, B. S. (1973). Prolonged Epileptic Seizures in Primates: Ischemic Cell Change and Its Relation to Ictal Physiological Events. Archives of Neurology. https://doi.org/10.1001/archneur.1973.00490190028002
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
